Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)
Public ClinicalTrials.gov record NCT06926842. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Phase 2 Trial of Once-Weekly Petrelintide Compared With Placebo in Participants With Overweight or Obesity and Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to investigate efficacy and safety of three doses of petrelintide versus placebo in participants with overweight or obesity and type 2 diabetes.
Study identification
- NCT ID
- NCT06926842
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 221 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 22, 2025 (Actual)
- Primary completion
- Aug 13, 2026 (Actual)
- Completion
- Aug 13, 2026 (Actual)
- Last update posted
- Sep 9, 2026
2025 – 2026
United States locations
- U.S. sites
- 48
- U.S. states
- 25
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cullman Clinical Trials - Family Medicine | Cullman | Alabama | 35055 | — |
| AZ Endocrine Institute | Chandler | Arizona | 85224 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| M3 Wake Research, Tucson Neuroscience Research, LLC | Tucson | Arizona | 85710 | — |
| Medical Investigation Inc | Little Rock | Arkansas | 72211-1847 | — |
| Velocity Clinical Research | Huntington Park | California | 90255 | — |
| Velocity Clinical Research, North Hollywood | North Hollywood | California | 91606 | — |
| Exalt Clinical Research | San Diego | California | 91910 | — |
| Diablo Clinical Research Inc. | Walnut Creek | California | 94598 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Emerson Clinical Research | Washington D.C. | District of Columbia | 20009 | — |
| Innovative Research of West Florida | Clearwater | Florida | 33756 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32204 | — |
| Solutions Through Advanced Research, Inc | Jacksonville | Florida | 32216 | — |
| M3 Wake Research - Lake City | Lake City | Florida | 32055 | — |
| West Orange Endocrinology P.A | Ocoee | Florida | 34761 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| M3 Wake Research - Atlanta | Atlanta | Georgia | 30328 | — |
| East Coast Institute for Research - Canton | Canton | Georgia | 30114 | — |
| Privia Medical Group Georgia, LLC | Savannah | Georgia | 31406 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Iowa Diabetes & Endocrinology Research Center | West Des Moines | Iowa | 50266 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67226 | — |
| DelRicht Research - New Orleans | New Orleans | Louisiana | 70115 | — |
| AAMRC | Flint | Michigan | 48504 | — |
| International Diabetes Center | Minneapolis | Minnesota | 55416 | — |
| Velocity Clinical Research, Gulfport | Gulfport | Mississippi | 39503 | — |
| AMR Kansas City | Kansas City | Missouri | 64114 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| M3 Wake Research - Las Vegas, NV | Las Vegas | Nevada | 89106 | — |
| Palm Research Center, Inc. | Las Vegas | Nevada | 89148 | — |
| Javara Inc | Charlotte | North Carolina | 28210 | — |
| PharmQuest Life Sciences, LLC | Greensboro | North Carolina | 27408 | — |
| M3 Wake Research | Raleigh | North Carolina | 27612 | — |
| Velocity Clinical Research, Cincinnati, Mt. Auburn | Cincinnati | Ohio | 45219 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Lynn Institute of Norman | Norman | Oklahoma | 73072 | — |
| M3 Wake Research - Charleston | Charleston | South Carolina | 29414 | — |
| M3 Wake Research/ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Elligo Clinical Research, Inc. | Austin | Texas | 78704 | — |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75390-8857 | — |
| Juno Research LLC | Houston | Texas | 77040 | — |
| Tekton Research, LLC | Irving | Texas | 75039 | — |
| Tekton Research, LLC | McKinney | Texas | 75069 | — |
| Texas Health Care, PLLC | San Marcos | Texas | 78666 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Texas Health Care | Stephenville | Texas | 76401 | — |
| Manaasas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06926842, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06926842 live on ClinicalTrials.gov.