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Recruiting Phase 3 Interventional

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

ClinicalTrials.gov ID: NCT07754461

Public ClinicalTrials.gov record NCT07754461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 5:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomised, Double-blind, Parallel-group, 56-week Study, Evaluating the Efficacy and Safety of Survodutide (BI 456906), Compared With Placebo, in Participants With Type 2 Diabetes, as an Adjunct to Diet and Physical Activity Alone or in Combination With Either Oral Antidiabetic Medications or Insulin

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study aims to find out whether a study medicine called survodutide helps people control their blood sugar. Adults who live with type 2 diabetes and with a body mass index (BMI) of 23 kg/m2 or higher can join. The study has 3 parts. In each part the study compares survodutide with placebo. Survodutide is being developed to treat several health problems including type 2 diabetes. Placebo looks like survodutide but does not contain any medicine. Depending on a person's diabetes treatment, a person will be assigned either to * Part A: healthy eating and physical activity * Part B: diabetes tablets (no injection of insulin) * Part C: injection of insulin (with or without diabetes tablets) Participants are randomly put into 1 of 3 groups, which means the group is chosen by chance. Two groups of participants get survodutide at different dose levels, and the third group gets placebo as injection under the skin once a week. You have a 2 in 3 chance of getting survodutide. During the study, participants continue their regular diabetes treatment. Participants are in the study for about 1 year and 2 months. During this time, they attend up to 12 visits at the site and receive at least 9 phone calls. Study doctors regularly test participants' blood sugar by checking their HbA1c values and other laboratory test results. The study doctor also regularly checks participants' health and takes note of any changes. For each study part, the results will be compared between the survodutide and the placebo group to see whether the treatment works.

Study identification

NCT ID
NCT07754461
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
600 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 24, 2026 (Actual)
Primary completion
Jan 17, 2028 (Estimated)
Completion
May 1, 2028 (Estimated)
Last update posted
Oct 14, 2026

2026 – 2028

United States locations

U.S. sites
88
U.S. states
30
U.S. cities
83
Facility City State ZIP Site status
Cahaba Research, Inc. - Trussville Location Birmingham Alabama 35235 Recruiting
Mission Research Institute - Gilbert Gilbert Arizona 85296 Not yet recruiting
Helios Clinical Research - Paradise Valley Paradise Valley Arizona 85253 Recruiting
Arizona Liver Health - Peoria 85381 Peoria Arizona 85381 Not yet recruiting
Helios Clinical Research - Phoenix Phoenix Arizona 85028 Recruiting
Woodland International Research Group, Inc. Little Rock Arkansas 72211 Recruiting
San Fernando Valley Health Canoga Park California 91304 Not yet recruiting
John Muir Physician Network Clinical Research Center Concord California 94520 Recruiting
Neighborhood Healthcare - Escondido Escondido California 92025 Recruiting
Clinical Trials Research - Lincoln Lincoln California 95648 Recruiting
ARK Clinical Research Long Beach California 90815 Recruiting
Infinity Clinical Research Norco California 92860 Not yet recruiting
Valley Clinical Trials, Inc. Northridge California 91325 Recruiting
Fomat Medical Research Oxnard California 93030 Recruiting
Encompass Clinical Research, Spring Valley Spring Valley California 91978 Recruiting
University Clinical Investigators, Inc. Tustin California 92780 Not yet recruiting
Diablo Clinical Research Walnut Creek California 94598 Recruiting
Focus Clinical Research West Hills California 91307 Recruiting
Clinical Research of West Florida, Inc. Clearwater Florida 33765 Recruiting
Northeast Research Institute Fleming Island Florida 32003 Recruiting
Covenant Metabolic Specialists, LLC - Fort Myers Fort Myers Florida 33912 Recruiting
Encore Medical Research Hollywood Florida 33024 Recruiting
Northeast Research Institute Jacksonville Florida 32204 Recruiting
Accel Research Sites - Lakeland Lakeland Florida 33803 Recruiting
Clinical Research of Central Florida - Lakeland Lakeland Florida 33805 Recruiting
Tampa Bay Medical Research - Largo Largo Florida 33777 Recruiting
New Horizon Research Center-Miami-69732 Miami Florida 33165 Recruiting
South Broward Research Miramar Florida 33027 Not yet recruiting
Covenant Metabolic Specialists, LLC - Brandon Riverview Florida 33578 Recruiting
Covenant Metabolic Specialists, LLC - Sarasota University Park Florida 34201 Recruiting
Metabolic Research Institute, Inc. West Palm Beach Florida 33401 Not yet recruiting
Encore Medical Research - Weston Weston Florida 33331 Recruiting
Conquest Research Winter Park Florida 32789 Recruiting
Centricity Research, Endocrine Consultants Columbus Georgia 31904 Recruiting
Javara-Fayetteville-67354 Fayetteville Georgia 30214 Recruiting
Balanced Life Health Care Solutions Lawrenceville Georgia 30046 Not yet recruiting
Rophe Adult and Pediatric Medicine Union City Georgia 30291 Not yet recruiting
Pacific Diabetes & Endocrine Center Honolulu Hawaii 96817 Not yet recruiting
Elite Clinical Trials - Blackfoot Blackfoot Idaho 83221 Recruiting
Family First Clinical Research Idaho Falls Idaho 83404 Not yet recruiting
Solaris Clinical Research Meridian Idaho 83646 Not yet recruiting
Evanston Premier Healthcare Research LLC Skokie Illinois 60077 Not yet recruiting
Cotton O'Neil Mulvane Topeka Kansas 66606 Recruiting
AMR Lexington Lexington Kentucky 40509 Recruiting
Endocrine and Metabolic Consultants Rockville Maryland 20852 Not yet recruiting
Northern Pines Health Center - Buckley Buckley Michigan 49620 Not yet recruiting
Revival Research Institute, LLC - Dearborn Dearborn Michigan 48126 Recruiting
Arcturus Healthcare - Troy Internal Medicine Research Division Troy Michigan 48098 Recruiting
International Diabetes Center Minneapolis Minnesota 55416 Not yet recruiting
Olive Branch Family Medical Center Olive Branch Mississippi 38654 Recruiting
SKY Clinical Research Network Group - Ridgeland Ridgeland Mississippi 39157 Not yet recruiting
StudyMetrix Research, LLC City of Saint Peters Missouri 63303 Recruiting
Logan Health Research - Kalispell Kalispell Montana 59901 Not yet recruiting
Boeson Research - Missoula Missoula Montana 59804 Not yet recruiting
Albuquerque Clinical Trials Albuquerque New Mexico 87102 Not yet recruiting
Ellipsis Research Group - Brooklyn Brooklyn New York 11215 Recruiting
Javara Inc. - Cape Fear Valley Medical Center Fayetteville North Carolina 28304 Recruiting
PharmQuest Life Sciences Greensboro North Carolina 27408 Recruiting
Centricity Research - Morehead City Morehead City North Carolina 28557 Recruiting
Diabetes & Endocrinology Associates of Stark County Canton Ohio 44718 Recruiting
Advanced Medical Research - Maumee Maumee Ohio 43537 Recruiting
New Venture Medical Research Wadsworth Ohio 44281 Recruiting
Tekton Research Oklahoma City Oklahoma City Oklahoma 73134 Recruiting
Heritage Valley Medical Group Beaver Pennsylvania 15009 Recruiting
Preferred Primary Care Physicians-Pittsburgh-63932 Pittsburgh Pennsylvania 15236 Recruiting
Preferred Primary Care Physicians Pittsburgh Pennsylvania 15243 Not yet recruiting
Preferred Primary Care Physicians - Matthew Drive Uniontown Pennsylvania 15401 Not yet recruiting
PanAmerican Clinical Research - Bluffton Bluffton South Carolina 29910 Not yet recruiting
Spartanburg Medical Research Spartanburg South Carolina 29303 Recruiting
University Diabetes & Endocrine Consultants Chattanooga Tennessee 37411 Recruiting
LifeDoc Research, PLLC Memphis Tennessee 38115 Not yet recruiting
Texas Diabetes and Endocrinology - Central Austin Austin Texas 78731 Recruiting
South Texas Research Institute - Brownsville Brownsville Texas 78520 Recruiting
Privia Medical Group Gulf Coast, PLLC Conroe Texas 77384 Recruiting
University of Texas Southwestern Medical Center Dallas Texas 75390-8837 Not yet recruiting
Pinnacle Clinical Research - Georgetown Georgetown Texas 78626 Recruiting
Juno Research, LLC Houston Texas 77040 Recruiting
Biopharma Informatic, Inc. Research Center Houston Texas 77084 Recruiting
Research Physicians Network Houston Texas 77089 Not yet recruiting
Southern Endocrinology Associates Mesquite Texas 75149 Not yet recruiting
Pinnacle Clinical Research - San Antonio San Antonio Texas 78222 Recruiting
Pinnacle Clinical Research, LLC San Antonio Texas 78229 Recruiting
Consano Clinical Research Shavano Park Texas 78231 Not yet recruiting
Texas Valley Clinical Research Weslaco Texas 78596 Not yet recruiting
Olympus Family Medicine Salt Lake City Utah 84117 Recruiting
Tidewater Physicians Multispecialty Group Newport News Virginia 23606 Not yet recruiting
ERA Health Research - Redmond Redmond Washington 98052 Recruiting
Clinical Investigation Specialists, Inc.-Kenosha-69111 Kenosha Wisconsin 53144 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07754461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 14, 2026 · Synced Oct 16, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07754461 live on ClinicalTrials.gov.

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