A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Public ClinicalTrials.gov record NCT07754461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomised, Double-blind, Parallel-group, 56-week Study, Evaluating the Efficacy and Safety of Survodutide (BI 456906), Compared With Placebo, in Participants With Type 2 Diabetes, as an Adjunct to Diet and Physical Activity Alone or in Combination With Either Oral Antidiabetic Medications or Insulin
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study aims to find out whether a study medicine called survodutide helps people control their blood sugar. Adults who live with type 2 diabetes and with a body mass index (BMI) of 23 kg/m2 or higher can join. The study has 3 parts. In each part the study compares survodutide with placebo. Survodutide is being developed to treat several health problems including type 2 diabetes. Placebo looks like survodutide but does not contain any medicine. Depending on a person's diabetes treatment, a person will be assigned either to * Part A: healthy eating and physical activity * Part B: diabetes tablets (no injection of insulin) * Part C: injection of insulin (with or without diabetes tablets) Participants are randomly put into 1 of 3 groups, which means the group is chosen by chance. Two groups of participants get survodutide at different dose levels, and the third group gets placebo as injection under the skin once a week. You have a 2 in 3 chance of getting survodutide. During the study, participants continue their regular diabetes treatment. Participants are in the study for about 1 year and 2 months. During this time, they attend up to 12 visits at the site and receive at least 9 phone calls. Study doctors regularly test participants' blood sugar by checking their HbA1c values and other laboratory test results. The study doctor also regularly checks participants' health and takes note of any changes. For each study part, the results will be compared between the survodutide and the placebo group to see whether the treatment works.
Study identification
- NCT ID
- NCT07754461
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2026 (Actual)
- Primary completion
- Jan 17, 2028 (Estimated)
- Completion
- May 1, 2028 (Estimated)
- Last update posted
- Oct 14, 2026
2026 – 2028
United States locations
- U.S. sites
- 88
- U.S. states
- 30
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research, Inc. - Trussville Location | Birmingham | Alabama | 35235 | Recruiting |
| Mission Research Institute - Gilbert | Gilbert | Arizona | 85296 | Not yet recruiting |
| Helios Clinical Research - Paradise Valley | Paradise Valley | Arizona | 85253 | Recruiting |
| Arizona Liver Health - Peoria 85381 | Peoria | Arizona | 85381 | Not yet recruiting |
| Helios Clinical Research - Phoenix | Phoenix | Arizona | 85028 | Recruiting |
| Woodland International Research Group, Inc. | Little Rock | Arkansas | 72211 | Recruiting |
| San Fernando Valley Health | Canoga Park | California | 91304 | Not yet recruiting |
| John Muir Physician Network Clinical Research Center | Concord | California | 94520 | Recruiting |
| Neighborhood Healthcare - Escondido | Escondido | California | 92025 | Recruiting |
| Clinical Trials Research - Lincoln | Lincoln | California | 95648 | Recruiting |
| ARK Clinical Research | Long Beach | California | 90815 | Recruiting |
| Infinity Clinical Research | Norco | California | 92860 | Not yet recruiting |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | Recruiting |
| Fomat Medical Research | Oxnard | California | 93030 | Recruiting |
| Encompass Clinical Research, Spring Valley | Spring Valley | California | 91978 | Recruiting |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | Not yet recruiting |
| Diablo Clinical Research | Walnut Creek | California | 94598 | Recruiting |
| Focus Clinical Research | West Hills | California | 91307 | Recruiting |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | Recruiting |
| Northeast Research Institute | Fleming Island | Florida | 32003 | Recruiting |
| Covenant Metabolic Specialists, LLC - Fort Myers | Fort Myers | Florida | 33912 | Recruiting |
| Encore Medical Research | Hollywood | Florida | 33024 | Recruiting |
| Northeast Research Institute | Jacksonville | Florida | 32204 | Recruiting |
| Accel Research Sites - Lakeland | Lakeland | Florida | 33803 | Recruiting |
| Clinical Research of Central Florida - Lakeland | Lakeland | Florida | 33805 | Recruiting |
| Tampa Bay Medical Research - Largo | Largo | Florida | 33777 | Recruiting |
| New Horizon Research Center-Miami-69732 | Miami | Florida | 33165 | Recruiting |
| South Broward Research | Miramar | Florida | 33027 | Not yet recruiting |
| Covenant Metabolic Specialists, LLC - Brandon | Riverview | Florida | 33578 | Recruiting |
| Covenant Metabolic Specialists, LLC - Sarasota | University Park | Florida | 34201 | Recruiting |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | Not yet recruiting |
| Encore Medical Research - Weston | Weston | Florida | 33331 | Recruiting |
| Conquest Research | Winter Park | Florida | 32789 | Recruiting |
| Centricity Research, Endocrine Consultants | Columbus | Georgia | 31904 | Recruiting |
| Javara-Fayetteville-67354 | Fayetteville | Georgia | 30214 | Recruiting |
| Balanced Life Health Care Solutions | Lawrenceville | Georgia | 30046 | Not yet recruiting |
| Rophe Adult and Pediatric Medicine | Union City | Georgia | 30291 | Not yet recruiting |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96817 | Not yet recruiting |
| Elite Clinical Trials - Blackfoot | Blackfoot | Idaho | 83221 | Recruiting |
| Family First Clinical Research | Idaho Falls | Idaho | 83404 | Not yet recruiting |
| Solaris Clinical Research | Meridian | Idaho | 83646 | Not yet recruiting |
| Evanston Premier Healthcare Research LLC | Skokie | Illinois | 60077 | Not yet recruiting |
| Cotton O'Neil Mulvane | Topeka | Kansas | 66606 | Recruiting |
| AMR Lexington | Lexington | Kentucky | 40509 | Recruiting |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | Not yet recruiting |
| Northern Pines Health Center - Buckley | Buckley | Michigan | 49620 | Not yet recruiting |
| Revival Research Institute, LLC - Dearborn | Dearborn | Michigan | 48126 | Recruiting |
| Arcturus Healthcare - Troy Internal Medicine Research Division | Troy | Michigan | 48098 | Recruiting |
| International Diabetes Center | Minneapolis | Minnesota | 55416 | Not yet recruiting |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654 | Recruiting |
| SKY Clinical Research Network Group - Ridgeland | Ridgeland | Mississippi | 39157 | Not yet recruiting |
| StudyMetrix Research, LLC | City of Saint Peters | Missouri | 63303 | Recruiting |
| Logan Health Research - Kalispell | Kalispell | Montana | 59901 | Not yet recruiting |
| Boeson Research - Missoula | Missoula | Montana | 59804 | Not yet recruiting |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | Not yet recruiting |
| Ellipsis Research Group - Brooklyn | Brooklyn | New York | 11215 | Recruiting |
| Javara Inc. - Cape Fear Valley Medical Center | Fayetteville | North Carolina | 28304 | Recruiting |
| PharmQuest Life Sciences | Greensboro | North Carolina | 27408 | Recruiting |
| Centricity Research - Morehead City | Morehead City | North Carolina | 28557 | Recruiting |
| Diabetes & Endocrinology Associates of Stark County | Canton | Ohio | 44718 | Recruiting |
| Advanced Medical Research - Maumee | Maumee | Ohio | 43537 | Recruiting |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | Recruiting |
| Tekton Research Oklahoma City | Oklahoma City | Oklahoma | 73134 | Recruiting |
| Heritage Valley Medical Group | Beaver | Pennsylvania | 15009 | Recruiting |
| Preferred Primary Care Physicians-Pittsburgh-63932 | Pittsburgh | Pennsylvania | 15236 | Recruiting |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15243 | Not yet recruiting |
| Preferred Primary Care Physicians - Matthew Drive | Uniontown | Pennsylvania | 15401 | Not yet recruiting |
| PanAmerican Clinical Research - Bluffton | Bluffton | South Carolina | 29910 | Not yet recruiting |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | Recruiting |
| University Diabetes & Endocrine Consultants | Chattanooga | Tennessee | 37411 | Recruiting |
| LifeDoc Research, PLLC | Memphis | Tennessee | 38115 | Not yet recruiting |
| Texas Diabetes and Endocrinology - Central Austin | Austin | Texas | 78731 | Recruiting |
| South Texas Research Institute - Brownsville | Brownsville | Texas | 78520 | Recruiting |
| Privia Medical Group Gulf Coast, PLLC | Conroe | Texas | 77384 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-8837 | Not yet recruiting |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | Recruiting |
| Juno Research, LLC | Houston | Texas | 77040 | Recruiting |
| Biopharma Informatic, Inc. Research Center | Houston | Texas | 77084 | Recruiting |
| Research Physicians Network | Houston | Texas | 77089 | Not yet recruiting |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | Not yet recruiting |
| Pinnacle Clinical Research - San Antonio | San Antonio | Texas | 78222 | Recruiting |
| Pinnacle Clinical Research, LLC | San Antonio | Texas | 78229 | Recruiting |
| Consano Clinical Research | Shavano Park | Texas | 78231 | Not yet recruiting |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | Not yet recruiting |
| Olympus Family Medicine | Salt Lake City | Utah | 84117 | Recruiting |
| Tidewater Physicians Multispecialty Group | Newport News | Virginia | 23606 | Not yet recruiting |
| ERA Health Research - Redmond | Redmond | Washington | 98052 | Recruiting |
| Clinical Investigation Specialists, Inc.-Kenosha-69111 | Kenosha | Wisconsin | 53144 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07754461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07754461 live on ClinicalTrials.gov.