A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Public ClinicalTrials.gov record NCT07754461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomised, Double-blind, Parallel-group, 56-week Study, Evaluating the Efficacy and Safety of Survodutide (BI 456906), Compared With Placebo, in Participants With Type 2 Diabetes, as an Adjunct to Diet and Physical Activity Alone or in Combination With Either Oral Antidiabetic Medications or Insulin
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study aims to find out whether a study medicine called survodutide helps people control their blood sugar. Adults who live with type 2 diabetes and with a body mass index (BMI) of 23 kg/m2 or higher can join. The study has 3 parts. In each part the study compares survodutide with placebo. Survodutide is being developed to treat several health problems including type 2 diabetes. Placebo looks like survodutide but does not contain any medicine. Depending on a person's diabetes treatment, a person will be assigned either to * Part A: healthy eating and physical activity * Part B: diabetes tablets (no injection of insulin) * Part C: injection of insulin (with or without diabetes tablets) Participants are randomly put into 1 of 3 groups, which means the group is chosen by chance. Two groups of participants get survodutide at different dose levels, and the third group gets placebo as injection under the skin once a week. You have a 2 in 3 chance of getting survodutide. During the study, participants continue their regular diabetes treatment. Participants are in the study for about 1 year and 2 months. During this time, they attend up to 12 visits at the site and receive at least 9 phone calls. Study doctors regularly test participants' blood sugar by checking their HbA1c values and other laboratory test results. The study doctor also regularly checks participants' health and takes note of any changes. For each study part, the results will be compared between the survodutide and the placebo group to see whether the treatment works.
Study identification
- NCT ID
- NCT07754461
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2026
- Primary completion
- Jan 16, 2028
- Completion
- Apr 30, 2028
- Last update posted
- Aug 9, 2026
2026 – 2028
United States locations
- U.S. sites
- 89
- U.S. states
- 31
- U.S. cities
- 84
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research, Inc. - Trussville Location | Birmingham | Alabama | 35235 | — |
| Gilbert Center for Family Medicine | Gilbert | Arizona | 85296 | — |
| Helios Clinical Research - Paradise Valley | Paradise Valley | Arizona | 85253 | — |
| Arizona Liver Health - Peoria 85381 | Peoria | Arizona | 85381 | — |
| Helios Clinical Research - Phoenix | Phoenix | Arizona | 85028 | — |
| Woodland International Research Group, Inc. | Little Rock | Arkansas | 72211 | — |
| San Fernando Valley Health | Canoga Park | California | 91304 | — |
| John Muir Physician Network Clinical Research Center | Concord | California | 94520 | — |
| Neighborhood Healthcare - Escondido | Escondido | California | 92025 | — |
| Clinical Trials Research - Lincoln | Lincoln | California | 95648 | — |
| ARK Clinical Research | Long Beach | California | 90815 | — |
| Infinity Clinical Research | Norco | California | 92860 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Fomat Medical Research | Oxnard | California | 93030 | — |
| Encompass Clinical Research, Spring Valley | Spring Valley | California | 91978 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Diablo Clinical Research | Walnut Creek | California | 94598 | — |
| Focus Clinical Research | West Hills | California | 91307 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Covenant Metabolic Specialists, LLC - Fort Myers | Fort Myers | Florida | 33912 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| Northeast Research Institute | Jacksonville | Florida | 32204 | — |
| Accel Research Sites - Lakeland | Lakeland | Florida | 33803 | — |
| Clinical Research of Central Florida - Lakeland | Lakeland | Florida | 33805 | — |
| Tampa Bay Medical Research - Largo | Largo | Florida | 33777 | — |
| New Horizon Research Center-Miami-69732 | Miami | Florida | 33165 | — |
| South Broward Research | Miramar | Florida | 33027 | — |
| Covenant Metabolic Specialists, LLC - Brandon | Riverview | Florida | 33578 | — |
| Covenant Metabolic Specialists, LLC - Sarasota | University Park | Florida | 34201 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Encore Medical Research - Weston | Weston | Florida | 33331 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Centricity Research, Endocrine Consultants | Columbus | Georgia | 31904 | — |
| Javara-Fayetteville-67354 | Fayetteville | Georgia | 30214 | — |
| Balanced Life Health Care Solutions | Lawrenceville | Georgia | 30046 | — |
| Rophe Adult and Pediatric Medicine | Union City | Georgia | 30291 | — |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96817 | — |
| Elite Clinical Trials - Blackfoot | Blackfoot | Idaho | 83221 | — |
| Family First Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Evanston Premier Healthcare Research LLC | Skokie | Illinois | 60077 | — |
| Cotton O'Neil Mulvane | Topeka | Kansas | 66606 | — |
| AMR Lexington | Lexington | Kentucky | 40509 | — |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | — |
| Northern Pines Health Center - Buckley | Buckley | Michigan | 49620 | — |
| Revival Research Institute, LLC - Dearborn | Dearborn | Michigan | 48126 | — |
| Arcturus Healthcare - Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| International Diabetes Center | Minneapolis | Minnesota | 55416 | — |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654 | — |
| SKY Clinical Research Network Group - Ridgeland | Ridgeland | Mississippi | 39157 | — |
| StudyMetrix Research, LLC | City of Saint Peters | Missouri | 63303 | — |
| Logan Health Research - Kalispell | Kalispell | Montana | 59901 | — |
| Boeson Research - Missoula | Missoula | Montana | 59804 | — |
| Palm Research Center | Las Vegas | Nevada | 89128 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Ellipsis Research Group - Brooklyn | Brooklyn | New York | 11215 | — |
| Cape Fear Valley Medical Center | Fayetteville | North Carolina | 28304 | — |
| PharmQuest Life Sciences | Greensboro | North Carolina | 27408 | — |
| Centricity Research - Morehead City | Morehead City | North Carolina | 28557 | — |
| Diabetes & Endocrinology Associates of Stark County | Canton | Ohio | 44718 | — |
| Advanced Medical Research - Maumee | Maumee | Ohio | 43537 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | — |
| Tekton Research-Edmond-68875 | Edmond | Oklahoma | 73013 | — |
| Heritage Valley Medical Group | Beaver | Pennsylvania | 15009 | — |
| Preferred Primary Care Physicians-Pittsburgh-63932 | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15243 | — |
| Preferred Primary Care Physicians - Matthew Drive | Uniontown | Pennsylvania | 15401 | — |
| PanAmerican Clinical Research - Bluffton | Bluffton | South Carolina | 29910 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| University Diabetes & Endocrine Consultants | Chattanooga | Tennessee | 37411 | — |
| LifeDoc Research, PLLC | Memphis | Tennessee | 38115 | — |
| Texas Diabetes and Endocrinology | Austin | Texas | 78731 | — |
| South Texas Research Institute - Brownsville | Brownsville | Texas | 78520 | — |
| Privia Medical Group Gulf Coast, PLLC | Conroe | Texas | 77384 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-8837 | — |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | — |
| Juno Research, LLC | Houston | Texas | 77040 | — |
| Biopharma Informatic, Inc. Research Center | Houston | Texas | 77084 | — |
| Research Physicians Network | Houston | Texas | 77089 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Pinnacle Clinical Research - San Antonio | San Antonio | Texas | 78222 | — |
| Pinnacle Clinical Research, LLC | San Antonio | Texas | 78229 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | — |
| Olympus Family Medicine | Salt Lake City | Utah | 84117 | — |
| Tidewater Physicians Multispecialty Group | Newport News | Virginia | 23606 | — |
| ERA Health Research - Redmond | Redmond | Washington | 98052 | — |
| Clinical Investigation Specialists, Inc.-Kenosha-69111 | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07754461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 9, 2026 · Synced Aug 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07754461 live on ClinicalTrials.gov.