A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease Treated With Once Daily Basal Insulin Alone or in Combination With Metformin, SGLT2i, or Both
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT07931547. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
Efficacy and Safety of Zenagamtide s.c. Once Weekly Compared to Placebo in Participants With Type 2 Diabetes and Chronic Kidney Disease Inadequately Controlled on Once Daily Basal Insulin Alone or in Combination With Metformin, SGLT2i, or Both
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is testing zenagamtide in participants with type 2 diabetes and chronic kidney disease. The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have type 2 diabetes. Participants will either get zenagamtide or placebo. Which treatment participants get is decided by chance. Zenagamtide is a new medicine that doctors cannot prescribe yet, but it has been tested in humans before.
Study identification
- NCT ID
- NCT07931547
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 450 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 10, 2026 (Estimated)
- Primary completion
- Jul 31, 2028 (Estimated)
- Completion
- Sep 25, 2028 (Estimated)
- Last update posted
- Nov 12, 2026
2026 – 2028
United States locations
- U.S. sites
- 26
- U.S. states
- 8
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scripps Whittier Diabetes Inst | La Jolla | California | 92037 | — |
| First Valley Medical Group | Lancaster | California | 93534 | — |
| Headlands Research CTR Lincoln | Lincoln | California | 95648 | — |
| North America Research Institute | San Dimas | California | 91773 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Encore Medical Research LLC | Hollywood | Florida | 33024 | — |
| My Preferred Research | Miami | Florida | 33155 | — |
| Adult Medicine of Lake County, Inc | Mt. Dora | Florida | 32757 | — |
| West Orange Endocrinology | Ocoee | Florida | 34761 | — |
| Florida Inst For Clin Res LLC | Orlando | Florida | 32825 | — |
| Care Access | Tamarac | Florida | 33321 | — |
| Encore Medical Research of Weston | Weston | Florida | 33331 | — |
| Palm Research Center Inc-Vegas | Las Vegas | Nevada | 89148 | — |
| DM Clinical | Brooklyn | New York | 11220 | — |
| University of North Carolina Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Holston Medical Group Pc | Bristol | Tennessee | 37620-7352 | — |
| Southeast Renal Research Institute | Chattanooga | Tennessee | 37404 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Victorium Clinical Research | Houston | Texas | 77024 | — |
| Prolato Clinical Research Cntr | Houston | Texas | 77054 | — |
| Southwest Clinical Trials | Houston | Texas | 77081 | — |
| Medical Colleagues-Texas LLP | Katy | Texas | 77450 | — |
| Northeast Clinical Research of San Antonio | San Antonio | Texas | 78233 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07931547, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 12, 2026 · Synced Nov 14, 2026
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