Condition Directory

Parkinson's Disease clinical trials

Directory of U.S. ClinicalTrials.gov public records for Parkinson's Disease. Browse Parkinson's Disease recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 15, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 15, 2026, 2:59 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

256

Shown on this page

Current sort

How Parkinson's Disease studies are organized in the registry

Records generally use the registry spelling “Parkinson disease.” The portfolio mixes drug studies with a high share of device, exercise, and rehabilitation research, so the study-type filter is unusually useful here. Disease-stage language (“early,” “advanced,” “levodopa-treated”) commonly appears in titles.

Terms that often appear in related listings

early Parkinson deep brain stimulation levodopa gait

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 217–228 of 256 matching trials for Parkinson's Disease.

Live ClinicalTrials.gov results.

Active filters: "levodopa" Clear condition filters

Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

Open in full search

Conditions: Parkinson's Disease
Interventions: PARCOPA; Drug
Lead sponsor: UCB Pharma; Industry
Eligibility: 18 Years and older
Timeline: 2004
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Advanced Parkinson's Disease
Interventions: Rotigotine, Placebo; Drug
Lead sponsor: UCB Pharma; Industry
Eligibility: 30 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 26
States / cities: Birmingham, Alabama • Gilbert, Arizona • Fountain Valley, California + 23 more

Conditions: Parkinson Disease
Interventions: Placebo, Pramipexole; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 30 Years and older
Enrollment: 511 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 10
States / cities: Sun City, Arizona • Tempe, Arizona • La Jolla, California + 7 more

Conditions: Parkinson's Disease, Motor Fluctuations
Interventions: DM-1992, Sinemet IR; Drug
Lead sponsor: Depomed; Industry
Eligibility: 30 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 7
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Long Beach, California + 4 more

Conditions: Parkinson's Disease
Interventions: AAV-hAADC-2; Genetic
Lead sponsor: Genzyme, a Sanofi Company; Industry
Eligibility: 40 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Idiopathic Parkinson's Disease
Interventions: Safinamide (as add-on therapy); Drug
Lead sponsor: Newron Pharmaceuticals SPA; Industry
Eligibility: 30 Years to 80 Years
Enrollment: 679 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 31
States / cities: Birmingham, Alabama • Phoenix, Arizona • Oxnard, California + 27 more

Conditions: Parkinson's Disease
Interventions: Parcopa; Drug
Lead sponsor: UCB Pharma; Industry
Eligibility: 40 Years and older
Timeline: 2005
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Parkinson's Disease
Interventions: Istradefylline; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson's Disease
Interventions: 2 mg perampanel, 4 mg perampanel, placebo comparator; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 30 Years and older
Enrollment: 752 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 99
States / cities: Birmingham, Alabama • Huntsville, Alabama • Peoria, Arizona + 82 more

Conditions: Parkinson's Disease With Cognitive Impairments
Interventions: safinamide, placebo; Drug
Lead sponsor: Newron Pharmaceuticals SPA; Industry
Eligibility: 45 Years to 80 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 9
States / cities: Sunnyvale, California • Jacksonville, Florida • Atlanta, Georgia + 5 more

Conditions: Gait Disorders, Neurologic
Interventions: droxidopa; Drug
Lead sponsor: Chelsea Therapeutics; Industry
Eligibility: 30 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: West Bloomfield, Michigan

Conditions: Idiopathic Parkinson's Disease
Interventions: Safinimide 50-100 mg/day, Matching Placebo; Drug
Lead sponsor: Newron Pharmaceuticals SPA; Industry
Eligibility: 30 Years to 80 Years
Enrollment: 549 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 28
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 24 more

About this Parkinson's Disease clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Parkinson's Disease as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Parkinson's Disease.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Parkinson's Disease clinical trials

How Parkinson's Disease studies are organized in the registry

Filter and sort this condition

Live official records

A Multicenter, Open-label Trial to Assess Subject Preference of PARCOPA, Carbidopa/Levodopa Orally Disintegrating Tablets, Compared to Conventional Carbidopa/Levodopa Tablets in Subjects With Stable Parkinson's Disease

Effect of Rotigotine on Motor Symptoms in Patients With Advanced Parkinson's Disease (PD) With Motor Fluctuations and Symptoms of Gastrointestinal Dysfunction

Long-term Safety Study of Open-label Pramipexole Extended Release (ER) in Patients With Early Parkinson´s Disease (PD).

Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations

A Study of AAV-hAADC-2 in Subjects With Parkinson's Disease

MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist

A Single Center, Randomized, Double-blind, Crossover Pilot Trial Comparing the Onset of Action of Parcopa™ With Sinemet® in Subjects With Stable Parkinson's Disease

Study of KW-6002 (Istradefylline) in Parkinson's Disease in Patients With Motor Response Complications on Levodopa

Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations

A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease

Study to Assess Droxidopa in the Treatment of Freezing Of Gait Symptoms in Patients With Parkinson's Disease

Safinamide in Idiopathic Parkinson's Disease (IPD) With Motor Fluctuations, as add-on to Levodopa

About this Parkinson's Disease clinical trials directory page