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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:45 PM EDT

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Showing 241–264 of 625 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adult Obesity Clear all
Active, not recruiting Phase 2 Interventional

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

NCT07441252
View directory record Official record
Conditions
Overweight or Obesity and Elevated Liver Fat
Interventions
Maridebart cafraglutide, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
23
States / cities
Chandler, Arizona • Phoenix, Arizona • Tucson, Arizona + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining the Longitudinal Relationship Between Sleep and Weight Gain in College Students

NCT04100967
View directory record Official record
Conditions
Healthy, Overweight
Interventions
Not listed
Lead sponsor
Oakland University
Other
Eligibility
17 Years to 22 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Rochester, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Phase 1 Interventional

Effects of Betahistine Hydrochloride in Overweight Women

NCT00459992
View directory record Official record
Conditions
Obesity, Overweight, Overnutrition
Interventions
Betahistine Hydrochloride
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Great Plains Internet Wellness Study for Aging

NCT04461184
View directory record Official record
Conditions
Internet Based Wellness Program, Obesity, Adult Population
Interventions
Internet Wellness Intervention for Aging
Behavioral
Lead sponsor
North Dakota State University
Other
Eligibility
65 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Inhibitory Control Training in Eating Behaviors

NCT03599115
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Inhibitory Control Training
Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 45 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional

Understanding Variability in Behavioral Weight Loss Treatment Response in Young Women (Ready SET Health)

NCT04875091
View directory record Official record
Conditions
Weight Loss, Weight Change, Body, Overweight or Obesity
Interventions
Ready SET Health
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Inhibitory Control Adult Weight Management

NCT04747886
View directory record Official record
Conditions
Overweight and Obesity
Interventions
WW Only, WW + PolyRules!
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional

The BMI Project (Body, Mind, Inflammation)

NCT04023318
View directory record Official record
Conditions
Overweight and Obesity, Chronic Inflammation
Interventions
Integrated Lifestyle Intervention
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 17, 2026, 11:45 PM EDT
Active, not recruiting Phase 2 Interventional

A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight

NCT06973720
View directory record Official record
Conditions
Obesity, Overweight or Obesity
Interventions
MET097, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Hollywood, Florida • Tampa, Florida • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Active, not recruiting Phase 2 Interventional

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

NCT07215559
View directory record Official record
Conditions
Obesity, Overweight, Diabetes Mellitus, Type 2
Interventions
Macupatide, Eloralintide, Macupatide Placebo, Eloralintide Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
26
States / cities
Gilbert, Arizona • Phoenix, Arizona • Tucson, Arizona + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic Intervention Study

NCT06030362
View directory record Official record
Conditions
Obesity, Food Addiction
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Phase 1 Interventional

A Study of ABBV-295 Subcutaneous Injections to Assess Pharmacokinetics and Adverse Events in Healthy Adult Women Participants With Overweight or Obesity Taking Oral Contraceptives

NCT07414784
View directory record Official record
Conditions
Healthy Volunteer
Interventions
ABBV-295, Levonorgestrel/Ethinyl Estradiol
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Anaheim, California • Grayslake, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MOWI Research Pilot

NCT03104192
View directory record Official record
Conditions
Obesity
Interventions
Develop & Refine MOWI w/o Amulet, MOWI Weight Loss Maintenance, Develop & Refine MOWI w Fitbit, Develop & Refine MOWI w Fitbit/Protein
Behavioral · Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance and Aerobic Exercise With Nutritional Supplementation in Men and Women

NCT00812409
View directory record Official record
Conditions
Obesity
Interventions
Whey protein supplementation with exercise, Non protein supplementation with exercise (control)
Dietary Supplement · Other
Lead sponsor
Purdue University
Other
Eligibility
35 Years to 65 Years
Enrollment
580 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
View directory record Official record
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study

NCT05055362
View directory record Official record
Conditions
Chronic Kidney Diseases, Overweight and Obesity
Interventions
Honey Spice Group
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 17, 2026, 11:45 PM EDT
Active, not recruiting Not applicable Interventional

4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity

NCT06399276
View directory record Official record
Conditions
Breast Cancer
Interventions
Weight Loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed No phase listed Observational

Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

NCT02849977
View directory record Official record
Conditions
Pro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene Mutations
Interventions
Not listed
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
2 Years and older
Enrollment
5,966 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
48
States / cities
Birmingham, Alabama • Chandler, Arizona • Mesa, Arizona + 38 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults

NCT02911753
View directory record Official record
Conditions
Obesity, Hypercholesterolemia, Hyperglycemia, Hypertriglyceridemia
Interventions
Mediterranean Lemonade, Green Tea, Flavored Water
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional

Teaching Obesity Treatment Options to Adult Learners (TOTAL): A Multisite RCT

NCT05346575
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Teaching Obesity Treatments to Adult Learners (TOTAL), Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
West Los Angeles, California • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Not applicable Interventional Results available

The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults

NCT04931836
View directory record Official record
Conditions
Obesity, Overweight, Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Type 2 Diabetes Mellitus, Type 2 Diabetes Mellitus in Obese
Interventions
Physical Activity Intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 64 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 17, 2026, 11:45 PM EDT
Active, not recruiting Not applicable Interventional

Daily Caloric Restriction in ADPKD

NCT04907799
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney, Overweight and Obesity
Interventions
Daily caloric restriction, Standard advice control
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 17, 2026, 11:45 PM EDT
Recruiting Phase 1 Interventional

A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity

NCT07803744
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Overweight, Obesity
Interventions
Tirzepatide, Acetaminophen, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 17, 2026, 11:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pounds Off Digitally (POD): The Use of Podcasting and Mobile Media to Promote Weight Loss

NCT01139255
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Podcasting + mobile media
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2011 · Synced Oct 17, 2026, 11:45 PM EDT