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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:04 AM EDT

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Showing 97–120 of 625 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adult Obesity Clear all
Completed Not applicable Interventional

THE ENLIGHTEN STUDY

NCT03261453
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Active Elipse Device, Elipse Sham Device
Device
Lead sponsor
Allurion Technologies
Industry
Eligibility
22 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
12
States / cities
Scottsdale, Arizona • Aurora, Colorado • Bolingbrook, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Cardiovascular Risk Factors in Black Young Adults

NCT04412954
View directory record Official record
Conditions
Obesity
Interventions
Smartphone + Text Messaging with Health Coach
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
17 Years to 25 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 2 Interventional

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

NCT05669599
View directory record Official record
Conditions
Obesity, Overweight, Type 2 Diabetes Mellitus
Interventions
Maridebart Cafraglutide, Placebo
Biological · Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 99 Years
Enrollment
592 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
29
States / cities
Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults

NCT00581074
View directory record Official record
Conditions
Obesity
Interventions
diet (grapefruit or grapefruit juice)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 27, 2011 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mHealth Intervention for Older Adults

NCT03398590
View directory record Official record
Conditions
Type2 Diabetes, Obesity
Interventions
self-regulation theory-based mHealth behavior intervention
Behavioral
Lead sponsor
Boston College
Other
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Oct 17, 2026, 9:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Project Health Intervention Among Latinx Adults in Primary Care

NCT04090515
View directory record Official record
Conditions
Obesity
Interventions
Project Health, Educational Video Control
Behavioral · Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 17, 2026, 9:04 AM EDT
Completed No phase listed Observational

WeDosify Real World Evidence (RWE) Study: Personalized Semaglutide Dosing in U.S. Adults

NCT07216651
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Not listed
Lead sponsor
Closed Loop Medicine
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Supervised and Unsupervised Physical Activity Programs During a Weight Loss Intervention for Adults

NCT02693132
View directory record Official record
Conditions
Obesity
Interventions
Supervised (SUP-PA), Unsupervised (UNSUP-PA), Step-based (STEP)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 2 Interventional Results available

ADJUnct Semaglutide Treatment in Type 1 Diabetes

NCT05537233
View directory record Official record
Conditions
Type 1 Diabetes, Obesity
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
Viral N. Shah
Other
Eligibility
18 Years to 65 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Aurora, Colorado • West Des Moines, Iowa • Detroit, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 17, 2026, 9:04 AM EDT
Recruiting Phase 2 Interventional

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

NCT07783802
View directory record Official record
Conditions
Atherosclerosis, Cardiovascular Disease, Obesity, Hypertension, Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
Interventions
Clazakizumab, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
30
States / cities
Huntsville, Alabama • Tucson, Arizona • Glendora, California + 24 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adults With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications

NCT03818256
View directory record Official record
Conditions
Antipsychotic-induced Weight Gain (AIWG)
Interventions
Miricorilant, Placebo
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
27
States / cities
Bentonville, Arkansas • Little Rock, Arkansas • Culver City, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

NCT06171945
View directory record Official record
Conditions
Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity
Interventions
AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 39 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Statewide (Rhode Island and Neighboring States) Partnerships for Worksite Weight Management

NCT00288145
View directory record Official record
Conditions
Overweight, Obesity
Interventions
WOW, Working On Wellness weight management
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 1, 2013 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

NCT02347007
View directory record Official record
Conditions
Obesity, Overweight, Fatty Liver, Metabolic Syndrome X
Interventions
Almond, Cereal Bar
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
30 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Weight Management Intervention for Youth and Young Adults With Autism Spectrum Disorder

NCT03865719
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Healthy Habits for Life
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
8 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Oct 17, 2026, 9:04 AM EDT
Recruiting Not applicable Interventional

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

NCT06724406
View directory record Official record
Conditions
Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
Interventions
Family Skills Training Session Quantity: 5, Family Skills Training Session Mode: In-person, Family Skills Training Content: Communication, Family Skills Training Content: Cohesion, Family Skills Training Session Quantity: 10, Family Skills Training Session Mode: Online, Family Skills Training Content: No Communication, Family Skills Training Content: No Cohesion
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults

NCT03100058
View directory record Official record
Conditions
Obesity, Overweight
Interventions
LIK066, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
59
States / cities
Anniston, Alabama • Jasper, Alabama • Beverly Hills, California + 52 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 17, 2026, 9:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Adding L-BAIBA to Exercising Adult Overweight and Obese Men and Women

NCT05775016
View directory record Official record
Conditions
Obesity, Weight Loss, Weight, Body, Cardiometabolic Syndrome
Interventions
Exercise
Behavioral
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

Bioavailability of SPMs in Obese Humans

NCT04701138
View directory record Official record
Conditions
Obesity Adult Onset
Interventions
SPM Active
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
50 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Oct 17, 2026, 9:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Interrupting Prolonged Sitting With Bouts of Physical Activity on Neurocognitive Function in Obesity

NCT04926207
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity Breaks Intervention, Talking Breaks Control
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 64 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Weight Loss on Foot Structure and Function in Obese Adults: A Pilot Study

NCT01782144
View directory record Official record
Conditions
Obesity
Interventions
NutriSystem portion-controlled pre-packaged meals
Other
Lead sponsor
Temple University
Other
Eligibility
50 Years to 75 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 17, 2026, 9:04 AM EDT
Completed No phase listed Observational

Body Heat Content and Dissipation in Obese and Normal Weight Adults

NCT00266500
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 17, 2026, 9:04 AM EDT
Recruiting Not applicable Interventional

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571
View directory record Official record
Conditions
Obesity, Multiple Chronic Conditions
Interventions
Prescriptive, Behavioral
Other · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 17, 2026, 9:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Toleration and Pharmacokinetics of Single Intravenous Doses of Peptide YY in Overweight Adults

NCT00331175
View directory record Official record
Conditions
Obesity
Interventions
Peptide YY3-36
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 15, 2006 · Synced Oct 17, 2026, 9:04 AM EDT