Independent directory Public ClinicalTrials.gov records United States
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Showing 121–144 of 1,077 matching trials from the live ClinicalTrials.gov search.
Conditions
Obstructive Sleep Apnea
Interventions
MATRx plus test
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Sleep Disordered Breathing, Nocturnal Oxygen Desaturation, Upper Airway Edema
Interventions
Forty-five degrees elevated upper body position, non-elevated upper body position, Noninvasive wrist pulse oximeter (WristOx Model 3150), Stop-Bang questionnaire, Epworth Sleepiness Scale, P-SAP Score, self-reported pain
Procedure · Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea, Down Syndrome
Interventions
Atomoxetine and oxybutynin (ato-oxy)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tucson, Arizona
Completed No phase listed Observational Accepts healthy volunteers

The Pathogenesis of OSA in People Living With HIV

NCT03064204
Conditions
Obstructive Sleep Apnea, HIV/AIDS
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 79 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Diego, California
Conditions
Excessive Sleepiness
Interventions
Armodafinil, Placebo
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Burlingame, California • San Diego, California • Stanford, California + 5 more
Conditions
Lung Diseases, Sleep Apnea Syndromes, Hypertension
Interventions
Continuous Positive Airway Pressure (CPAP) Treatment, Sham CPAP device - CPAP device with pressure delivered <1 cm H20
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
4
States / cities
Denver, Colorado • Atlanta, Georgia • Long Island City, New York + 1 more
Recruiting Phase 1Phase 2 Interventional

Trazodone on OSA Endotypes

NCT06286189
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral tablet, Trazodone Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea
Interventions
Donepezil, placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Conditions
Obstructive Sleep Apnea
Interventions
S9 Elite with Acclimate, S9 Elite
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Sleep Aging and Risk for Alzheimer's 2.0

NCT03278119
Conditions
Alzheimer Disease, Sleep Apnea
Interventions
PET Scan and nocturnal polysomnography
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 75 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
New York, New York
Not yet recruiting Phase 2Phase 3 Interventional

A Study Of Synthetic THC And Sleep

NCT07570953
Conditions
Obstructive Sleep Apnea
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Determine Results of Vibratory Stimulus on Subject's Neck

NCT01491828
Conditions
Sleep Apnea, Snoring
Interventions
Kai Strap
Device
Lead sponsor
Kai Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Honolulu, Hawaii
Conditions
Sleep Apnea, Obstructive Sleep Apnea
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
North Haven, Connecticut
Conditions
Sleep Apnea, Obstructive
Interventions
Oxytocin Intranasal Spray, Placebo Intranasal Spray
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Obstructive Sleep Apnea
Interventions
Bright light therapy glasses
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Circadian Rhythms and Cardiovascular Risk

NCT02202811
Conditions
Obstructive Sleep Apnea
Interventions
Forced Desynchrony
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sleep and Breathing in the General Population - Chemical Stimuli

NCT04720547
Conditions
Sleep-disordered Breathing
Interventions
Zolpidem, No Treatment
Drug · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Obstructive Sleep Apnea, Sleep Apnea, OSA
Interventions
FRESCA mask first night, CPAP Mask first night
Device
Lead sponsor
FRESCA Medical
Industry
Eligibility
18 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Fresno, California • Murrieta, California • Hollywood, Florida + 2 more
Conditions
Bronchopulmonary Dysplasia, Apnea of Prematurity
Interventions
Caffeine, Placebo (dextrose)
Drug
Lead sponsor
Wayne State University
Other
Eligibility
Up to 4 Weeks
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Head and Neck Cancer, Obstructive Sleep Apnea
Interventions
Nerve stimulation using nerve stimulation device and sterile wire electrode.
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Obstructive Sleep Apnea
Interventions
Fitbit, OSA questionnaire, Polysomnography
Device · Other · Diagnostic Test
Lead sponsor
Vidya Raman
Other
Eligibility
3 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Obstructive Sleep Apnea
Interventions
Polysomnogram
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Xyrem (X), Zolpidem (Z), Modafinil (M), Placebo (P)
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
St. Petersburg, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea and Vascular Function

NCT01717339
Conditions
OSA
Interventions
Sleep Study
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota