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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:46 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Osteoarthritis
Interventions: Physical training program, Self-management training program, Physical training and self-management training programs; Other · Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 35 Years to 64 Years
Enrollment: 294 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Osteoarthritis, Hip
Interventions: ReNu™ Injection; Other
Lead sponsor: NuTech Medical, Inc; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Redwood City, California • Chicago, Illinois

Conditions: Osteoarthritis
Interventions: TDS-943 (topical diclofenac sodium 4% spray), celecoxib, placebo; Drug · Other
Lead sponsor: Mika Pharma GmbH; Industry
Eligibility: 40 Years and older
Enrollment: 650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 49
States / cities: Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 42 more

Conditions: Osteoarthritis
Interventions: Supartz, Euflexxa; Device
Lead sponsor: Bioventus LLC; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Pain After Total Knee Arthroplasty, Osteoarthritis Pain
Interventions: Open-label flexibly dosed milnacipran; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Osteoarthritis
Interventions: Mini Incision Approach, 2 Incision Approach; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Joint Diseases, Osteoarthritis, Hip, Rheumatoid Arthritis, Psoriatic Arthritis, Avascular Necrosis of Hip
Interventions: Routine Total Hip Arthroplasty; Device
Lead sponsor: Ortho Development Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Post Traumatic Arthritis, Osteoarthritis, Total Ankle Replacement, Total Ankle Prosthesis
Interventions: Total Ankle Replacement; Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 21 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2038
U.S. locations: 5
States / cities: Morton Grove, Illinois • South Bend, Indiana • Louisville, Kentucky + 2 more

Conditions: Osteoarthritis, Knee Pain
Interventions: SL-1002, Placebo; Drug
Lead sponsor: Saol Therapeutics Inc; Industry
Eligibility: 35 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 15
States / cities: Greenwood Village, Colorado • Washington D.C., District of Columbia • Coral Gables, Florida + 12 more

Conditions: Osteoarthritis Post-meniscectomy
Interventions: Bone Marrow Aspirate Concentrate, Standard Meniscectomy; Biological · Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Osteoarthritis, Knee
Interventions: MISHA Knee System, Non-Surgical Treatment; Device · Other
Lead sponsor: Moximed; Industry
Eligibility: Not listed
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 9
States / cities: Davis, California • Oceanside, California • Sacramento, California + 6 more

Conditions: Osteoarthritis
Interventions: Adalimumab; Drug
Lead sponsor: Stanford University; Other
Eligibility: 45 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Stanford, California

Conditions: Knee Osteoarthritis
Interventions: Mind-body exercise and education; Behavioral
Lead sponsor: Tufts Medical Center; Other
Eligibility: 50 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis
Interventions: [StroMed + platelet rich plasma (PRP)], [PRP] platelet rich plasma; Biological
Lead sponsor: VivaTech International, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 4,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Grove City, Pennsylvania

Conditions: Anxiety, Osteoarthritis
Interventions: Music via Headphones; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Osteoarthritis
Interventions: Diet & Exercise, Attention Control; Behavioral
Lead sponsor: Wake Forest University; Other
Eligibility: 50 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Cherokee, North Carolina • Winston-Salem, North Carolina

Conditions: Chronic Pain, Osteoarthritis
Interventions: MS Contin, Placebo; Drug
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 30 Years to 65 Years · Male only
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Osteoarthritis, Knee
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Post-Traumatic Osteoarthritis of Ankle, Ankle Osteoarthritis, Ankle Injuries
Interventions: Osteochondral allograft ankle; Procedure
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 55 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 55 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Osteoarthritis
Interventions: Patient education in self-care of knee OA; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 40 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2001
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Knee Osteoarthritis
Interventions: Corticosteroid injection; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 40 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Osteoarthritis, Degenerative Joint Disease
Interventions: Bupivicaine + epinephrine, Bupivacaine, Ropivacaine, Ketorolac, Clonidine Injection; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Total Knee Arthroplasty, Osteoarthritis
Interventions: Computer Assisted Navigation Knee Replacement; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Jacksonville, Florida

Search by objective public record fields.

Community-Based Programs for Improving Physical Function in People With Early Knee Osteoarthritis

ReNu™ Injection to Treat Hip Osteoarthritis Study

Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial II

Non-Inferiority Study Comparing 3 Weekly Injections of SUPARTZ® vs 3 Weekly Injections of Euflexxa® for Knee OA

Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)

Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement

Survivorship and Patient Outcomes of Primary Total Hip Arthroplasty With the Ovation Hip System

A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain

Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy

MOTION Clinical Trial

A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee

Preoperative Music Intervention for Anxiety in Hip and Knee Arthroplasty

The Cherokee Study: Cherokee Health for Elderly Residents With Osteoarthritis of the Knee

Hormone Function in Men Treated for Pain With Opioids or Placebo

A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKA

Indications for Osteochondral Allograft Transplantation

PROs Following Low-dose Irradiation for Osteoarthritis

Effects of Comprehensive Care for Knee OA

Do Knee Injections Offer Benefit With Knee Arthritis Pain

Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement

Computer Assisted Total Knee Replacement