Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Osteo Arthritis Knee
Interventions: V120083, Naproxen, Placebo; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 291 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 30
States / cities: Birmingham, Alabama • Tuscumbia, Alabama • North Hollywood, California + 24 more

Conditions: Chronic Knee Pain
Interventions: Photobiomodulation therapy (PBM) device, Sham PBM device; Device
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Obesity
Interventions: Not listed
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 20 Years to 60 Years
Enrollment: 177 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Bilateral Primary Osteoarthritis of Knee
Interventions: Autologous Bone Marrow Aspirate Concentrate, Sterile saline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Osteoarthritis
Interventions: Doxycycline, Cefazolin; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 40 Years to 90 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Knee Osteoarthritis
Interventions: Implementation Strategy: Foundational Arm, Implementation Strategy: REACH Arm; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Osteoarthritis
Interventions: Amniotic Suspension Allograft, Placebo; Biological · Drug
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 516 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 38
States / cities: Birmingham, Alabama • Mobile, Alabama • Glendale, Arizona + 30 more

Conditions: Osteoarthritis
Interventions: Canakinumab, Placebo to canakinumab, Naproxen, Placebo to Naproxen; Biological · Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 8
States / cities: Anniston, Alabama • Mesa, Arizona • San Diego, California + 5 more

Conditions: Arthroplasty, Replacement, Hip
Interventions: Tritanium® Primary Acetabular Shell; Device
Lead sponsor: Stryker Orthopaedics; Industry
Eligibility: 18 Years and older
Enrollment: 275 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2023
U.S. locations: 7
States / cities: St. Helena, California • Tampa, Florida • Lexington, Kentucky + 4 more

Conditions: Osteoarthritis, Degenerative Joint Disease
Interventions: Care Navigator, Standard Post-Operative TKA Care; Behavioral · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years and older
Enrollment: 308 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Muscle Atrophy, ACL Reconstruction, Trauma, Osteoarthritis
Interventions: Testosterone, Placebo; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
Interventions: Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic, Muscle relaxant during maintenance anesthesia, Pain control with fentanyl, Bispectral Index (BIS) monitoring for depth of anesthesia, Spinal Anesthesia, Midazolam administered during spinal anesthesia, Cerebrospinal fluid collection, Administration of intrathecal morphine; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 65 Years and older
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Osteoarthritis, Knee
Interventions: Aquatic Prehab; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 50 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Osteoarthritis, Knee
Interventions: Device: Robotic MAKO total knee, FocusMotion knee brace, Fitbit tracking device, FocusMotion app; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Creve Coeur, Missouri

Conditions: Chronic Pain, Osteoarthritis
Interventions: active low-intensity transcranial electrical stimulation/active transcranial ultrasound, Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Knee Osteoarthritis
Interventions: HYMOVIS, Placebo; Device
Lead sponsor: Fidia Farmaceutici s.p.a.; Industry
Eligibility: 40 Years and older
Enrollment: 332 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 21
States / cities: Birmingham, Alabama • Brimingham, Alabama • Phoenix, Arizona + 17 more

Conditions: Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
Interventions: Ceramax Acetabular System; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: Not listed
Enrollment: 185 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 12
States / cities: Sacramento, California • Denver, Colorado • Fort Collins, Colorado + 8 more

Conditions: Osteoarthritis, Low Back Pain
Interventions: COV795; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 18 Years and older
Enrollment: 376 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 42
States / cities: Tucson, Arizona • Anaheim, California • Buena Park, California + 33 more

Conditions: Osteoarthritis, Post-traumatic; Arthrosis
Interventions: Sidus Stem-Free Shoulder; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: Not listed
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 4
States / cities: Louisville, Kentucky • Baltimore, Maryland • Philadelphia, Pennsylvania

Conditions: Knee Osteoarthritis, Hip Osteoarthritis, Knee Arthritis, Hip Arthritis
Interventions: Total knee or Hip Arthroplasty; Procedure
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Osteoarthritis
Interventions: Osteoarthritis Intervention; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 21 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Arthropathy of Knee Joint
Interventions: Weight-bearing biofeedback exercise, Standard of care exercise; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years to 85 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Osteoarthritis
Interventions: Ropivacaine, Normal saline, Methylprednisolone; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Chronic Pain, Osteoarthritis
Interventions: transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

Obesity and the Initiation of Knee Osteoarthritis

Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis

Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?

Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee

Tritanium® Primary Acetabular Shell Study

Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial

Testosterone Administration and ACL Reconstruction in Men

Shaping Anesthetic Techniques to Reduce Post-operative Delirium

Prehabilitation Using Aquatic Exercise

MAKO Total Knee Artroplasty

Effects of tDCS and tUS on Pain Perception in OA of the Knee

Safety and Effectiveness Study of a Non-Crosslinked HA Alkylamide HYADD(TM) 4 Hydrogel for Osteoarthritis of the Knee

28mm Ceramic-on-Ceramic Total Hip Replacement Study

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

Long Term Sidus PMCF

An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty

Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback

Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis

Effects of tDCS and tUS on Pain Perception in OA of the Knee