- Conditions
- Surfactant, Respiratory Distress Syndrome (Neonatal)
- Interventions
- Surfactant Administration through Laryngeal or Supraglottic Airway, Surfactant Administration through Thin Catheter
- Procedure
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 0 Hours to 72 Hours
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Dallas, Texas
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Showing 25–48
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- Conditions
- Atelectasis, Bronchoscopy
- Interventions
- Bronchoscopic procedure
- Device
- Lead sponsor
- Ambu A/S
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Preterm Delivery
- Interventions
- dosing of Betamethasone
- Drug
- Lead sponsor
- The Cooper Health System
- Other
- Eligibility
- 16 Years to 45 Years · Female only
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 2
- States / cities
- Camden, New Jersey • Pomona, New Jersey
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements, FEV1, FVC, Atelectasis, Pneumonia, Re-intubation, Hospital Length of Stay, Nursing Workload, Incentive Spirometry
- Interventions
- Use-recording, patient-reminder alarm for incentive spirometry
- Behavioral
- Lead sponsor
- Lifespan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Neonatal Respiratory Distress
- Interventions
- Simulation
- Behavioral
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Respiratory Distress of Newborn
- Interventions
- Ultrasound
- Device
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- Up to 6 Months
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Madison, Wisconsin
- Conditions
- Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications, Patient Adherence, Incentive Spirometry, Respiratory Therapy, Respiratory Insufficiency
- Interventions
- Alarms
- Device
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Ventilation, Breathing, Atelectasis
- Interventions
- Volumetric Incentive Spirometry, EzPAP® POSITIVE AIRWAY PRESSURE
- Device
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Atelectasis Neonatal, Pneumothorax and Air Leak
- Interventions
- Detecting asymmetric lung disease like atelectasis or pneumothorax with electrical impedance tomography (EIT)
- Other
- Lead sponsor
- Sharp HealthCare
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Pre-Term, Respiratory Distress of Newborn, Premature
- Interventions
- Point of care lung ultrasound
- Diagnostic Test
- Lead sponsor
- Hackensack Meridian Health
- Other
- Eligibility
- 34 Weeks to 36 Weeks
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Hackensack, New Jersey
- Conditions
- Atelectasis
- Interventions
- Incentive Spirometry, EzPAP® Positive Airway Pressure
- Device
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
- Interventions
- Infasurf Aero™
- Combination Product
- Lead sponsor
- ONY
- Industry
- Eligibility
- 29 Weeks to 36 Weeks
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 6 more
- Conditions
- Obesity, Respiratory Insufficiency, Right-Sided Heart Failure, Pulmonary Atelectasis, Respiratory Mechanics
- Interventions
- PEEP INCREMENTAL, PEEP DECREMENTAL
- Procedure
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Respiratory Distress Syndrome, Newborn
- Interventions
- Surfactant administered via Laryngeal Mask Airway (LMA), standard of care (nasal CPAP and supplemental oxygen)
- Device · Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- Up to 72 Hours
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Malignant Neoplasms of Respiratory and Intrathoracic Organs, Lung Neoplasm
- Interventions
- Bronchoscopy, Radial Probe Endobronchial Ultrasound
- Procedure
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Heart Transplant Failure, Anesthesia
- Interventions
- Lung Recruitment
- Other
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- Not listed
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging, Respiratory Mechanics, Electrical Impedance Tomography, Trans-Thoracic Echocardiography
- Interventions
- Non-Invasive Ventilation, Esophageal catheter positioning
- Procedure
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Atelectasis
- Interventions
- FiO2 (fraction of inspired oxygen) 0.3 plus PEEP (positive end expiratory pressure) 3 -5 cm water, FiO2 0.3 without PEEP, FiO2 >0.9 with 3-5 cm water PEEP, FiO2 >0.9 without PEEP
- Other
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Neonatal Respiratory Distress
- Interventions
- RAM Nasal Cannula
- Other
- Lead sponsor
- Englewood Hospital and Medical Center
- Other
- Eligibility
- 28 Weeks to 42 Weeks
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Englewood, New Jersey
- Conditions
- Preterm Infants, Respiratory Distress Syndrome (Neonatal), BPD - Bronchopulmonary Dysplasia
- Interventions
- Pressure Targeted High Flow, CPAP
- Procedure
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 7 Days to 40 Weeks
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- San Diego, California • Austin, Texas
- Conditions
- Pulmonary Complication, Dyspnea, Pneumonia, COPD, CHF, Atelectasis, PE
- Interventions
- Incentive Spirometry
- Behavioral
- Lead sponsor
- Jewish Hospital, Cincinnati, Ohio
- Other
- Eligibility
- 65 Years to 99 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Respiratory Failure
- Interventions
- Hypertonic saline (3%), Placebo (0.9% saline)
- Drug
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Pulmonary Edema, Pneumonia, Atelectasis, Pleural Effusion, Acute Rejection of Lung Transplant (Disorder), Airway Obstruction, Rib Fractures, Acute Copd Exacerbation, Asthma COPD, Pulmonary Embolism, Hemothorax, Pneumothorax, Mesothelioma, Diaphragmatic Paralysis
- Interventions
- Portable Dynamic Digital Radiography (DDR)
- Diagnostic Test
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 230 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Atelectasis
- Interventions
- The MetaNeb® System
- Device
- Lead sponsor
- Hill-Rom
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Newport Beach, California