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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Atheroscleroses, Cerebral Clear all
Completed No phase listed Observational Accepts healthy volunteers

Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke

NCT03990545
View directory record Official record
Conditions
Intracranial Atherosclerosis, Acute Stroke, Transient Ischemic Attack
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Jun 10, 2026, 7:27 PM EDT
Withdrawn Phase 2 Interventional

Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation

NCT02995642
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal, Carotid Atherosclerosis
Interventions
18F-FPPRGD2, Positron emission tomography, Computed tomography, Magnetic Resonance Imaging
Drug · Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

Intracranial Atherosclerosis and Depression After Coronary Artery Bypass Graft

NCT01838356
View directory record Official record
Conditions
Depression, Intracranial Atherosclerosis, Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
40 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
New Haven, Connecticut • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Identifying Genes That May Increase the Risk for Heart Disease in African Americans

NCT00344136
View directory record Official record
Conditions
Heart Diseases
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 95 Years
Enrollment
5,302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 28, 2016 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors

NCT00001589
View directory record Official record
Conditions
Carotid Atherosclerosis, Myocardial Infarction
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 10, 2026, 7:27 PM EDT
Recruiting Phase 3 Interventional

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

NCT04774159
View directory record Official record
Conditions
Peripheral Arterial Disease, Atherosclerosis of Extremities, Inflammation
Interventions
Colchicine 0.5 MG Oral Tablet, Colchicine-Placebo
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
6,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
19
States / cities
New Haven, Connecticut • Gainesville, Florida • Tampa, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 10, 2026, 7:27 PM EDT
Completed Phase 4 Interventional Results available

Reducing Total Cardiovascular Risk in an Urban Community

NCT00241904
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus, Atherosclerosis, Cerebral Arteriosclerosis, Hypertension
Interventions
Lifestyle Changes, Antiplatelet Agents, Beta Blocker, ACE Inhibitors
Behavioral · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Jun 10, 2026, 7:27 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Aliskiren Effect on Aortic Plaque Progression

NCT01417104
View directory record Official record
Conditions
Atherosclerosis
Interventions
Aliskiren, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
45 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Jun 10, 2026, 7:27 PM EDT
Terminated Phase 3 Interventional Results available

Niacin Plus Statin to Prevent Vascular Events

NCT00120289
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Coronary Disease, Atherosclerosis, Myocardial Infarction
Interventions
Extended release niacin, Simvastatin
Drug
Lead sponsor
Axio Research. LLC
Industry
Eligibility
45 Years and older
Enrollment
3,414 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
68
States / cities
Birmingham, Alabama • Hoover, Alabama • Pheonix, Arizona + 52 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Jun 10, 2026, 7:27 PM EDT
Not yet recruiting No phase listed Observational

Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

NCT06453252
View directory record Official record
Conditions
Stroke, Ischemic, Intracranial Atherosclerosis, Posterior Circulation Brain Infarction
Interventions
we are aiming to develop a Scoring system based on certain variables derived from both groups
Other
Lead sponsor
Sohag University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

Postprandial Lipoproteins and Atherosclerosis

NCT00005263
View directory record Official record
Conditions
Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases, Myocardial Ischemia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1990 – 1995
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Jun 10, 2026, 7:27 PM EDT
Completed Not applicable Interventional Results available

Assessment Of Vascular Health After Niacin Therapy (AVANT)

NCT02003638
View directory record Official record
Conditions
Coronary Artery Disease, Carotid Artery Disease, Peripheral Artery Disease
Interventions
Niacin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Jun 10, 2026, 7:27 PM EDT
Terminated Not applicable Interventional Results available

Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)

NCT00106938
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Stenosis, Stroke, Atherosclerosis
Interventions
Carotid artery stenting with filter (interventional), Carotid artery endarterectomy (surgical)
Device · Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 79 Years
Enrollment
1,663 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
62
States / cities
Phoenix, Arizona • Mountain View, California • Newport Beach, California + 52 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Jun 10, 2026, 7:27 PM EDT
Terminated No phase listed Observational

Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis

NCT03464851
View directory record Official record
Conditions
Carotid Artery Stenosis
Interventions
Carotid Stenotic Scan (CSS)
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Jun 10, 2026, 7:27 PM EDT
Active, not recruiting Phase 3 Interventional

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

NCT05739383
View directory record Official record
Conditions
Primary Prevention of Atherosclerotic Cardiovascular Disease
Interventions
Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, Placebo in 1.5ml
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
40 Years to 79 Years
Enrollment
14,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
243
States / cities
Birmingham, Alabama • Fairhope, Alabama • Foley, Alabama + 189 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jun 10, 2026, 7:27 PM EDT
Terminated Phase 3 Interventional

Aspirin Or Warfarin To Prevent Stroke

NCT00004728
View directory record Official record
Conditions
Stroke, Cerebral Infarction, Atherosclerosis, Constriction, Pathologic
Interventions
Warfarin, Aspirin
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2006 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

Plaque Inflammation and Dysfunctional HDL in AIM-HIGH

NCT00880178
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis, Myocardial Infarction
Interventions
Simvastatin and Extended-Release niacin, Simvastatin
Drug
Lead sponsor
University of Washington
Other
Eligibility
45 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • Long Beach, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Jun 10, 2026, 7:27 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

RLIP76 in Human Serum in Adults With Rheumatologic Diseases

NCT00861159
View directory record Official record
Conditions
Carotid Atherosclerosis
Interventions
Not listed
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2011 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

Identification of Genes Expressed in Atherosclerotic Plaque

NCT00353730
View directory record Official record
Conditions
Atherosclerosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 100 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 7, 2021 · Synced Jun 10, 2026, 7:27 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Carotid Risk Prediction (CRISP) Consortium

NCT04448353
View directory record Official record
Conditions
Carotid Atherosclerosis
Interventions
vascuCAP
Diagnostic Test
Lead sponsor
Elucid Bioimaging Inc.
Industry
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Baltimore, Maryland • Bethesda, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

11C-PIB PET Study in MESA at Columbia University

NCT03981380
View directory record Official record
Conditions
Cognitive Impairment, Vascular Diseases, Alzheimer Disease, Atherosclerosis
Interventions
11C-PIB
Drug
Lead sponsor
José A. Luchsinger
Other
Eligibility
60 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Jun 10, 2026, 7:27 PM EDT
Completed No phase listed Observational

Diabetes, Lipoproteins and Accelerated Vascular Disease

NCT00005479
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis, Carotid Artery Diseases, Diabetes Mellitus, Non-insulin Dependent, Diabetes Mellitus
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 75 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2015 · Synced Jun 10, 2026, 7:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stroke Prevention in the Wisconsin Native American Population

NCT04382963
View directory record Official record
Conditions
Stroke, Atherosclerosis
Interventions
High Risk - intensive coaching, High Risk - standard care, Low Risk - control
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Madison, Wisconsin • Oneida, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jun 10, 2026, 7:27 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PPG Project 3 - PET/MRI of the Brain-hematopoiesis-atherosclerosis Axis in PTSD Patients

NCT03279393
View directory record Official record
Conditions
PTSD, Trauma, Healthy
Interventions
fluorodeoxyglucose (FDG)-PET/MRI
Drug
Lead sponsor
Zahi Fayad
Other
Eligibility
30 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Jun 10, 2026, 7:27 PM EDT