- Conditions
- Major Depressive Episode Associated With Bipolar II Disorder
- Interventions
- NMRA-335140 80 mg, Placebo
- Drug
- Lead sponsor
- Neumora Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 21
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Garden Grove, California + 18 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 32
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Interventions
- Azetukalner, Placebo
- Drug
- Lead sponsor
- Xenon Pharmaceuticals Inc.
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 28
- States / cities
- Tucson, Arizona • Little Rock, Arkansas • Rogers, Arkansas + 23 more
- Conditions
- Bipolar Disorder Depression
- Interventions
- ABX-002
- Drug
- Lead sponsor
- Autobahn Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 14
- States / cities
- Walnut Creek, California • Cromwell, Connecticut • Hartford, Connecticut + 10 more
- Conditions
- Bipolar Depression
- Interventions
- Lumateperone, Placebo
- Drug · Other
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 381 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 14
- States / cities
- Birmingham, Alabama • Sherman Oaks, California • Miami, Florida + 11 more
- Conditions
- Bipolar I Depression
- Interventions
- RG2417, Placebo
- Drug
- Lead sponsor
- Repligen Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 36
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • San Diego, California + 33 more
- Conditions
- Bipolar Disorder
- Interventions
- Aripiprazole
- Drug
- Lead sponsor
- Cambridge Health Alliance
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2008
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Bipolar Depression
- Interventions
- Lumateperone (ITI-007), Placebo
- Drug
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 529 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 42
- States / cities
- Rogers, Arkansas • Cerritos, California • Costa Mesa, California + 39 more
- Conditions
- Major Depressive Disorder, Bipolar Depression, Suicidal Ideation
- Interventions
- Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy, Partial Sleep deprivation, Sleep Phase Delay, and Low amber light., Treatment as usual
- Behavioral · Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Bipolar Depression Depressed Phase
- Interventions
- Active Low Field Magnetic Stimulation, Sham Low Field Magnetic Stimulation
- Device
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Affective Psychosis, Bipolar, Manic Disorder, Manic-Depressive Psychosis, Mania, Manic State, Psychoses, Manic-Depressive
- Interventions
- Quetiapine fumarate (Seroquel) SR
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 447 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 51
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Cerritos, California + 48 more
- Conditions
- Bipolar I Disorder
- Interventions
- Aripiprazole, Placebo
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 650 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 40
- States / cities
- Mesa, Arizona • La Mesa, California • La Palma, California + 37 more
- Conditions
- Bipolar Disorder
- Interventions
- AZD4451, Placebo
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Bipolar I Disorder
- Interventions
- quetiapine fumarate, lithium, divalproex
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 710 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 36
- States / cities
- Birmingham, Alabama • Beverly Hills, California • Chula Vista, California + 33 more
- Conditions
- Bipolar Disorder, Cocaine Dependence
- Interventions
- Lamotrigine, Placebo
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Bipolar Disorder
- Interventions
- Seroquel®, quetiapine fumarate (atypical antipsychotic), lithium (mood stabilizer), divalproex (mood stabilizer)
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 710 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 81
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 78 more
- Conditions
- Bipolar Depression, Major Depressive Disorder
- Interventions
- Lumateperone, Placebos
- Drug
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 488 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 13
- States / cities
- Garden Grove, California • Oceanside, California • Sherman Oaks, California + 10 more
- Conditions
- Bipolar Depression
- Interventions
- ITI-007 (Lumateperone), Placebo
- Drug
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 554 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 55
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • Cerritos, California + 52 more
- Conditions
- Bipolar Disorder
- Interventions
- MCN36 (nutritional supplement), Placebo
- Drug
- Lead sponsor
- University of Calgary
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Bipolar Disorder, Depression
- Interventions
- PF-04455242
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 3
- States / cities
- New Haven, Connecticut
- Conditions
- Bipolar Depression
- Interventions
- Lurasidone, Placebo
- Drug
- Lead sponsor
- Sumitomo Pharma America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 356 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 22
- States / cities
- Costa Mesa, California • Riverside, California • San Diego, California + 16 more
- Conditions
- Bipolar Disorder, Bipolar Depression, Depression
- Interventions
- quetiapine fumarate (Seroquel), paroxetine, mood stabilizing activity
- Drug · Behavioral
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 676 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 28
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • National City, California + 25 more
- Conditions
- Bipolar Depression
- Interventions
- Uridine
- Drug
- Lead sponsor
- Repligen Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 80 participants
- Timeline
- Started 2006
- U.S. locations
- 11
- States / cities
- Stanford, California • Smyrna, Georgia • Indianapolis, Indiana + 8 more
- Conditions
- Bipolar Disorder
- Interventions
- Not listed
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Affective Psychosis, Bipolar, Depression, Bipolar, Manic-Depressive Psychosis, Psychoses, Manic-Depressive
- Interventions
- Quetiapine fumarate (Seroquel) SR
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 54
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 51 more