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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:15 PM EDT

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Showing 817–840 of 6,941 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Body Weight Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release

NCT05287906
View directory record Official record
Conditions
Overweight and Obesity, Type 2 Diabetes Mellitus
Interventions
Water, Glucose, Steviol Glycosides, Steviol Glycosides plus glucose, Rebaudioside A
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 50 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
3
States / cities
Miami Gardens, Florida • Naples, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional

Health Education Intervention in Reducing Weight Gain in Patients With Newly Diagnosed Stage I-IV Breast Cancer Undergoing Chemotherapy

NCT01941784
View directory record Official record
Conditions
Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
Interventions
educational intervention, counseling intervention, telephone-based intervention, questionnaire administration, quality-of-life assessment
Other · Behavioral · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2019 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 4 Interventional Results available

Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity

NCT03799198
View directory record Official record
Conditions
Obesity
Interventions
Weight Management Program (WMP), Medication for chronic weight management (Rx)
Other · Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 23, 2026, 9:15 PM EDT
Terminated Not applicable Interventional Results available

StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight

NCT00939055
View directory record Official record
Conditions
Obesity
Interventions
StomaphyX, Sham procedure
Device · Procedure
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 64 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Columbus, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Food Acceptance Through Positive Parenting: the Play and Grow Study

NCT06074926
View directory record Official record
Conditions
Obesity, Childhood, Overweight, Childhood, Overnutrition, Pediatric Obesity, Eating, Healthy
Interventions
Associative Conditioning, Repeated Exposure
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
3 Years to 5 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 3 Interventional

A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

NCT06548100
View directory record Official record
Conditions
Generalized Lipodystrophy
Interventions
mibavademab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
2 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Bethesda, Maryland • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Study of Factors Related to Exercise

NCT02010463
View directory record Official record
Conditions
Obesity
Interventions
Exercise
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2020
U.S. locations
2
States / cities
Kansas City, Kansas • Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 23, 2026, 9:15 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

NCT01017263
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Glucose Intolerance, Obesity
Interventions
Lis-dexamphetamine
Drug
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2014 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los

NCT06079658
View directory record Official record
Conditions
Obesity
Interventions
Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Conway, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 23, 2026, 9:15 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Low-calorie Diet in Isolated Impaired Fasting Glucose

NCT06451055
View directory record Official record
Conditions
Isolated Impaired Fasting Glucose
Interventions
Low-calorie diet, Routine dietary and physical activity habits
Behavioral
Lead sponsor
Emory University
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Results available

Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity

NCT05343000
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Home-based pulmonary rehabilitation (PR) system
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 2 Interventional Results available

Study to Examine Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight Subjects

NCT00673387
View directory record Official record
Conditions
Overweight, Obesity
Interventions
pramlintide acetate, metreleptin, placebo-P, placebo-M
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
636 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
36
States / cities
Birmingham, Alabama • Chandler, Arizona • Santa Rosa, California + 33 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PREDICT 2: Personalized Responses to Dietary Composition Trial 2

NCT03983733
View directory record Official record
Conditions
Diabetes, Heart Diseases, Diet Habit, Diet Modification, Microbial Colonization, Healthy, Obesity, Metabolism
Interventions
Dietary Intervention
Other
Lead sponsor
Zoe Global Limited
Other
Eligibility
18 Years to 70 Years
Enrollment
1,139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 23, 2026, 9:15 PM EDT
Withdrawn Not applicable Interventional

The Effect of Weight Loss on Psoriasis Area Severity Index in Adult Psoriasis Patients

NCT01137448
View directory record Official record
Conditions
Psoriasis, Obesity
Interventions
Weight Loss
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional

Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates

NCT00887393
View directory record Official record
Conditions
Morbid Obesity, Non-alcoholic Fatty Liver Disease
Interventions
low carbohydrate diet, low-fat diet
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 3 Interventional Results available

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

NCT00532779
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Naltrexone SR 16 mg/Bupropion SR 360 mg /day, Naltrexone SR 32 mg/Bupropion SR 360 mg /day, Placebo, Ancillary therapy
Drug · Behavioral
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,742 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
34
States / cities
Birmingham, Alabama • Fairhope, Alabama • Chandler, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2014 · Synced Oct 23, 2026, 9:15 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT06546670
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
ITU512, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
12 Years to 55 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
9
States / cities
Birmingham, Alabama • Miami, Florida • Boston, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT06619041
View directory record Official record
Conditions
Obesity, Overweight
Interventions
HealthyTogether
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Recruiting Early Phase 1 Interventional

Induction of Labor in Morbidly Obese Patients

NCT06199154
View directory record Official record
Conditions
Morbid Obesity, Pregnancy
Interventions
Misoprostol
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Not applicable Interventional Results available

Veteran Peer Coaches Optimizing and Advancing Cardiac Health

NCT02697422
View directory record Official record
Conditions
Cardiovascular Disease (CVD), Hypertension, Hyperlipemia, Obesity
Interventions
Community-based peer health coach intervention
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 75 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 23, 2026, 9:15 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Avoid and Resist Strategies for Weight Management

NCT05143931
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Home food environment and grocery delivery (AVOID), Inhibitory control training (RESIST), WW
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
14 Years and older
Enrollment
503 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 23, 2026, 9:15 PM EDT
Withdrawn Phase 4 Interventional

The Effect of add-on Canagliflozin in Patients With Type 2 Diabetes Treated With U-500 Insulin

NCT02597309
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Canagliflozin
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 3 Interventional

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Total Hip Replacement Surgery

NCT00697099
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Semuloparin sodium, Enoxaparin sodium, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
2,326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Oct 23, 2026, 9:15 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

NCT06948747
View directory record Official record
Conditions
Healthy Participants
Interventions
AZD5004, Rosuvastatin, Erythromycin, Atorvastatin, Simvastatin, Repaglinide
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Brooklyn, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 23, 2026, 9:15 PM EDT