Independent directory Public ClinicalTrials.gov records United States
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Showing 1081–1104 of 6,941 matching trials from the live ClinicalTrials.gov search.
Conditions
Overweight, Obese
Interventions
Motivational and Family Weight Loss, Basic Health Education, Online Intervention, Online Control
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
11 Years to 16 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
PTSD, Overweight and Obesity
Interventions
I MOVE!+UP
Behavioral
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Starting Pediatric Obesity Prevention in Pregnancy

NCT01279109
Conditions
Obesity, Pregnancy
Interventions
Social network building intervention, Home visit
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
16 Years to 99 Years · Female only
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional

Diet and Depression

NCT06252701
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Early Weight-Bearing After the Lapiplasty Mini-Incision Procedure (Mini3D)

NCT05082012
Conditions
Hallux Valgus, Bunion
Interventions
Treatment of Hallux Valgus
Device
Lead sponsor
Treace Medical Concepts, Inc.
Industry
Eligibility
14 Years to 58 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
10
States / cities
Decatur, Alabama • Hartselle, Alabama • Scottsdale, Arizona + 7 more
Conditions
Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias
Interventions
Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training
Dietary Supplement · Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Regulation of Muscle Protein Phenotype in Humans With Obesity

NCT04700800
Conditions
Obesity
Interventions
Exercise
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 45 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Scottsdale, Arizona
Conditions
Obesity
Interventions
Semaglutide, Placebo (semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
50
States / cities
Fairhope, Alabama • Beverly Hills, California • Los Angeles, California + 41 more
Conditions
Obesity, Overweight
Interventions
Taldefgrobep Alfa, Placebo
Drug
Lead sponsor
Biohaven Therapeutics Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
20
States / cities
Chula Vista, California • Montclair, California • Sacramento, California + 17 more
Completed Phase 1 Interventional Accepts healthy volunteers

Feasibility Study of Exenatide by Continuous Subcutaneous Infusion

NCT01857895
Conditions
Obesity
Interventions
Exenatide
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional

Helping Employees Lose Pounds

NCT02853877
Conditions
Weight Loss
Interventions
Weekly Incentive
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Breast Cancer, Obesity, Weight Changes
Interventions
Diet, Spiritual counseling
Behavioral · Other
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Obesity
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Small Extracellular Vesicles and Insulin Action

NCT05933707
Conditions
Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign
Interventions
People with Metabolically Unhealthy Obesity - Low Calorie Diet
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Physical Activity and Health Outcomes

NCT01833507
Conditions
Overweight, Obese
Interventions
Self-Exercise, Usual Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women

NCT01894581
Conditions
Obesity, Fertility
Interventions
LOVAZA, GnRH
Dietary Supplement · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Food for Thought: Executive Functioning Around Eating Among Children

NCT06108128
Conditions
Self-regulation, Appetitive Behavior, Eating Behavior, Child Obesity
Interventions
Executive functioning observational tasks
Other
Lead sponsor
Temple University
Other
Eligibility
4 Years to 6 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

NCT04791371
Conditions
Type 2 Diabetes, Overweight and Obesity
Interventions
Cardiovascular exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Charlottesville, Virginia
Completed No phase listed Observational Results available

Weight Change in PWS Over Six Months

NCT03585244
Conditions
Weight Change, Body
Interventions
weekly weight
Other
Lead sponsor
Foundation for Prader-Willi Research
Other
Eligibility
12 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Walnut, California
Conditions
Breast Cancer, Prostate Cancer, Melanoma (Skin), Endometrial Cancer, Gallbladder Cancer, Rectal Cancer, Kidney Cancer, Bladder Cancer
Interventions
Written Weight Loss Material, Weight Loss App, Behavioral Lifestyle Weight Loss Intervention (Coaching)
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Brain Dopamine Function in Human Obesity

NCT03648892
Conditions
Obesity, Healthy Volunteers, Overweight
Interventions
[c11] raclopride, [18F]fallypride
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Obesity
Interventions
CP-945,598
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Anaheim, California • Miami, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Phenolic Dependent And Independent Effects Of Whole Grain Sorghum On Immunometabolism

NCT07832071
Conditions
Dietary Intervention, Gut Microbiota, Insulin Sensitivity/Resistance, Obesity & Overweight
Interventions
Whole grain sumac sorghum, Whole grain white sorghum, White rice
Other
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Lincoln, Nebraska