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ClinicalTrials.gov public records Last synced Sep 16, 2026, 9:03 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Not yet recruiting Phase 1 Interventional

Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors

NCT07224568
View directory record Official record
Conditions
Solid Tumor (Excluding CNS), Hepatocellular Carcinoma, Liver Cell Carcinoma, Liposarcoma, Yolk Sac Tumor, Rhabdomyosarcoma
Interventions
SC-CAR.GPC3xIL15.21 CAR T cells
Biological
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2045
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Phase 1 Interventional

Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas

NCT01058850
View directory record Official record
Conditions
Brain Cancer, Brain Stem Tumors, Pontine Tumors
Interventions
Rindopepimut
Biological
Lead sponsor
Paul Graham Fisher
Other
Eligibility
3 Years to 18 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 16, 2026, 9:03 PM EDT
Completed No phase listed Observational

Osmotic Agent Use in Middle Cerebral Artery Stroke

NCT04156490
View directory record Official record
Conditions
Ischemic Stroke, MCA Infarction
Interventions
No intervention is planned, this will be a purely retrospective trial.
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Not applicable Interventional

A Prospective, Randomized Trial of Early Versus Late Tracheostomy in Trauma Patients With Severe Brain Injury

NCT00292097
View directory record Official record
Conditions
Respiratory Failure, Traumatic Brain Injury
Interventions
Early tracheostomy, Late tracheostomy
Procedure
Lead sponsor
Memorial Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Johnstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Sep 16, 2026, 9:03 PM EDT
Withdrawn Not applicable Interventional

The General Use of Robots in Stroke Recovery

NCT01726660
View directory record Official record
Conditions
Stroke
Interventions
IMT Robotic Arm therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 16, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Interactions Between PALS and Caregivers

NCT06819124
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Structured Communicative Interaction, Unstructured communicative interaction
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 90 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 16, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional

Pro-2-Cool Pivotal Trial II

NCT06929923
View directory record Official record
Conditions
Concussion, Mild
Interventions
Pro2Cool Device, Sham Cooling Garment Device
Device
Lead sponsor
TecTraum Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Ann Arbor, Michigan • Akron, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 16, 2026, 9:03 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

NCT03277638
View directory record Official record
Conditions
Glioblastoma, Adult
Interventions
Pembrolizumab at 7 days prior, Pembrolizumab at 14 days post, Pembrolizumab at 35 days post, Laser Interstitial Thermotherapy
Drug · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 16, 2026, 9:03 PM EDT
Enrolling by invitation No phase listed Observational

Feasibility of Lecanemab Registry and Clinical Outcome Measures

NCT06285448
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lecanemab
Drug
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 16, 2026, 9:03 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial Vaccination

NCT01239043
View directory record Official record
Conditions
Meningitis, Meningococcal Meningitis, Meningococcal Infections
Interventions
Menomune®: A, C, Y, W 135 Meningococcal Polysaccharide, Menactra®: Meningococcal (A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate
Biological
Lead sponsor
Sanofi
Industry
Eligibility
56 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
6
States / cities
Scottsdale, Arizona • Bardstown, Kentucky • Albuquerque, New Mexico + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2012 · Synced Sep 16, 2026, 9:03 PM EDT
Completed Phase 1 Interventional Results available

[F-18] Fluorothymidine (FLT) Imaging on Patients With Primary Brain Tumors

NCT00707343
View directory record Official record
Conditions
Cancer, Brain Tumors
Interventions
FLT-PET Imaging
Radiation
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Sep 16, 2026, 9:03 PM EDT
Completed No phase listed Observational

Measurement of Gait Using Opal APDM and Gait Mat in Parkinsonism

NCT02064543
View directory record Official record
Conditions
Parkinsonism
Interventions
GAITRite, ADPM
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Sep 16, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Connectomics in Psychiatric Classification

NCT03967535
View directory record Official record
Conditions
Dementia, Dementia Alzheimers, Frontotemporal Dementia, Pick's Disease With Dementia
Interventions
MRI Brain Imaging, Mental Health Assessment and Computerized Cognitive Test
Device · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 16, 2026, 9:03 PM EDT
Completed Not applicable Interventional

3-Dimensional Accelerometer Sub-Study

NCT01612689
View directory record Official record
Conditions
Epilepsy
Interventions
Accelerometer Device
Device
Lead sponsor
Cyberonics, Inc.
Industry
Eligibility
6 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Gainesville, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Phase 3 Interventional Results available

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

NCT02245568
View directory record Official record
Conditions
Alzheimer's Disease, Behavioral Variant Frontotemporal Dementia
Interventions
LMTM
Drug
Lead sponsor
TauRx Therapeutics Ltd
Industry
Eligibility
Not listed
Enrollment
913 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
57
States / cities
Phoenix, Arizona • Fountain Valley, California • Laguna Hills, California + 48 more
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 16, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional

Intrathecal Baclofen and Pediatric Dystonia

NCT06606574
View directory record Official record
Conditions
Dystonic Cerebral Palsy
Interventions
Titration protocol
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 16, 2026, 9:03 PM EDT
Completed Not applicable Interventional Results available

Development of a Multifunctional Rehabilitation Device for Persons With Parkinson's Disease

NCT05586490
View directory record Official record
Conditions
Parkinson Disease
Interventions
Multifunctional RehabilitationDevice (MRD), existing standard rehabilitation device
Device
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Phase 1 Interventional

RTA 744 Injection in Patients With Leptomeningeal Disease

NCT00512460
View directory record Official record
Conditions
Neoplastic Meningitis, Solid Tumor, Lymphoma, Leukemia, Brain Tumor
Interventions
RTA 744
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2016 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Phase 2 Interventional Results available

Sphenopalatine Ganglion Block for Headache After Concussion

NCT04650282
View directory record Official record
Conditions
Concussion, Headache
Interventions
Lidocaine in SphenoCath device, Saline Solution in SphenoCath device
Combination Product
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Sep 16, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Investigating the Neurobiology of Tinnitus

NCT01294124
View directory record Official record
Conditions
Tinnitus, Traumatic Brain Injury, Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 30 Years
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Sep 16, 2026, 9:03 PM EDT
Approved For Marketing No phase listed Expanded access

Long Term Study of the Safety of OXC XR as in Pediatric Epilepsy Subjects

NCT00918424
View directory record Official record
Conditions
Epilepsy
Interventions
Oxcarbazepine Extended Release
Drug
Lead sponsor
Supernus Pharmaceuticals, Inc.
Industry
Eligibility
4 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
6
States / cities
Loxahatchee Groves, Florida • Palm Beach, Florida • Rockville, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Sep 16, 2026, 9:03 PM EDT
Terminated Phase 3 Interventional Results available

Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)

NCT02907177
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Ponesimod, Placebo
Drug · Other
Lead sponsor
Actelion
Industry
Eligibility
18 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
26
States / cities
Birmingham, Alabama • Fresno, California • Pasadena, California + 22 more
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 16, 2026, 9:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Care Coordination System for People With Dementia

NCT04308512
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Dementia Alzheimers
Interventions
Active Nili device, Passive Nili system
Behavioral
Lead sponsor
Bijan Najafi, PhD
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 16, 2026, 9:03 PM EDT
Completed No phase listed Observational

Real World Testing of a Brain-Computer Interface

NCT04026581
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury, Speech Disorders
Interventions
Speech generating device (SGD) evaluation including BCI access, Training and treatment
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Carnegie, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 16, 2026, 9:03 PM EDT