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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Dysrhythmia Clear all
Terminated Phase 1 Interventional Results available

Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fibrillation

NCT01483183
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
OPC-108459, Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
9
States / cities
Washington D.C., District of Columbia • Hollywood, Florida • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Jul 24, 2026, 1:53 AM EDT
Completed No phase listed Observational

Study of the Wearable Defibrillator in Heart-Failure Patients

NCT01326624
View directory record Official record
Conditions
Heart Failure, Ventricular Dysfunction, Sudden Death, Sudden Cardiac Arrest, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
wearable defibrillator (LifeVest)
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 4 Interventional

A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke

NCT04126486
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Zio®XT Monitor
Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
70 Years and older
Enrollment
11,931 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
176
States / cities
Birmingham, Alabama • Guntersville, Alabama • Montgomery, Alabama + 141 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Jul 24, 2026, 1:53 AM EDT
Terminated Phase 4 Interventional Results available

Catheter Ablation of Arrhythmias to Improve CRT Response

NCT03035227
View directory record Official record
Conditions
Arrhythmia, Cardiac
Interventions
Catheter Ablation, Anti-Arrhythmics
Procedure · Drug
Lead sponsor
Kansas City Heart Rhythm Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Jul 24, 2026, 1:53 AM EDT
Withdrawn Not applicable Interventional

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

NCT03242720
View directory record Official record
Conditions
Obstructive Sleep Apnea, Atrial Fibrillation
Interventions
Cardiac Ablation for Atrial Fibrillation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 23, 2022 · Synced Jul 24, 2026, 1:53 AM EDT
Completed No phase listed Observational

THE GIRAFFE Study: Genomic Risk Markers for Atrial Fibrillation Following Extended Cardiac Rhythm Monitoring

NCT01970969
View directory record Official record
Conditions
Patients With Symptoms of Cardiac Arrhythmia at Risk for Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older
Enrollment
928 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Jul 24, 2026, 1:53 AM EDT
Recruiting No phase listed Observational

EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

NCT06212791
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Self- Report Evaluation-Duke Activity Status Index, Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire, Cardiopulmonary exercise test (CPET), Transthoracic echocardiogram, Ambulatory cardiac rhythm assessment, Cardiovascular magnetic resonance (CMR)
Behavioral · Diagnostic Test
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 3 Interventional

Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine

NCT01391091
View directory record Official record
Conditions
Migraine, Atrial Fibrillation
Interventions
Radiofrequency catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ST-segment Elevation as an AF Endophenotype

NCT01205529
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Procainamide
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 1 Interventional

Study of T3 on the Incidence of Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT00289367
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
triiodothyronine
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2008 · Synced Jul 24, 2026, 1:53 AM EDT
Terminated Phase 2 Interventional Results available

Metformin as an Upstream Therapy in Atrial Fibrillation

NCT02931253
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Metformin
Drug
Lead sponsor
The Guthrie Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Sayre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Jul 24, 2026, 1:53 AM EDT
Completed No phase listed Observational

Organization in Acute Atrial Fibrillation Post Open Heart Surgery

NCT00614107
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 79 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Jul 24, 2026, 1:53 AM EDT
Not listed No phase listed Observational

Outcomes of Functional Substrate Mapping of Ventricular Tachycardia

NCT05708131
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Not listed
Lead sponsor
Mid and South Essex NHS Foundation Trust
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Atrial Fibrillation, Cardiac Symptoms, and Anxiety

NCT02133365
View directory record Official record
Conditions
Atrial Fibrillation, Anxiety
Interventions
Mindfulness and Interoceptive Exposure
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 3 Interventional Results available

Ranolazine Implantable Cardioverter-Defibrillator Trial

NCT01215253
View directory record Official record
Conditions
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
Interventions
Ranolazine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
83
States / cities
Tucson, Arizona • Little Rock, Arkansas • East Palo Alto, California + 70 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

The LEADLESS II IDE Study for the Aveir VR Leadless Pacemaker System

NCT04559945
View directory record Official record
Conditions
Cardiac Rhythm Disorder, Bradycardia
Interventions
Aveir VR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
38
States / cities
Birmingham, Alabama • Huntsville, Alabama • Scottsdale, Arizona + 32 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 4 Interventional Results available

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

NCT03346057
View directory record Official record
Conditions
Reversal of Neuromuscular Blockade
Interventions
Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Sugammadex 16 mg/kg, Neostigmine + Glycopyrrolate, Rocuronium, Vecuronium
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • Loma Linda, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maestro Handheld Cardiac Monitor Validation

NCT02977104
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Maestro ECG
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jul 24, 2026, 1:53 AM EDT
Recruiting No phase listed Observational

Role of Novel ILR in the Management of PVCs

NCT06060548
View directory record Official record
Conditions
PVC - Premature Ventricular Contraction, Myocarditis
Interventions
Monitoring of patients presenting with PVCs
Other
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2022 – 2025
U.S. locations
6
States / cities
Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 24, 2026, 1:53 AM EDT
Terminated No phase listed Observational

PLUG Dementia Trial and MRI PLUG Dementia Sub-Study

NCT03091855
View directory record Official record
Conditions
Atrial Fibrillation, Dementia, Cognitive Decline
Interventions
Questionnaire, Magnetic Resonance Imaging
Other · Diagnostic Test
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
65 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jul 24, 2026, 1:53 AM EDT
Completed No phase listed Observational

Diagnostic Investigation of Sudden Cardiac Event Risk

NCT00500708
View directory record Official record
Conditions
Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Anchorage, Alaska • Palo Alto, California • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Jul 24, 2026, 1:53 AM EDT
Not listed Phase 2 Interventional

Sole-Therapy Treatment of Atrial Fibrillation

NCT00566176
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Surgical Ablation using the AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
5
States / cities
Tampa, Florida • Cincinnati, Ohio • Oklahoma City, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2013 · Synced Jul 24, 2026, 1:53 AM EDT
Completed Phase 2 Interventional

Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke

NCT00240643
View directory record Official record
Conditions
Fibrillation, Atrial, Atrial Fibrillation
Interventions
SB424323
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
9
States / cities
Mobile, Alabama • Troy, Michigan • Akron, Ohio + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jul 24, 2026, 1:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups

NCT00377702
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Jul 24, 2026, 1:53 AM EDT