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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:43 AM EDT

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Showing 625–648 of 2,293 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Ischemia Clear all
Completed Phase 3 Interventional Results available

Trial to Assess Chelation Therapy (TACT)

NCT00044213
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
EDTA, EDTA Placebo, High Dose Vitamin, High Dose Vitamin Placebo
Drug · Dietary Supplement
Lead sponsor
Mt. Sinai Medical Center, Miami
Other
Eligibility
50 Years and older
Enrollment
1,708 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2012
U.S. locations
73
States / cities
Little Rock, Arkansas • Danville, California • Fresno, California + 68 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

NCT07704918
View directory record Official record
Conditions
Melanoma
Interventions
Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran)
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
55 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 23, 2026, 8:43 AM EDT
Terminated Phase 3 Interventional

Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI

NCT00990327
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Apadenoson SPECT-MPI, Adenosine SPECT-MPI
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
863 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
103
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 87 more
Source: ClinicalTrials.gov public record
Updated May 1, 2012 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting No phase listed Observational

SSVC-CI During CABG

NCT06645327
View directory record Official record
Conditions
Coronary Artery Bypass Grafting Surgery (CABG)
Interventions
a change in operating room table position, which will mimic an IV fluid bolus
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 3 Interventional Results available

NEXUS Study for the Treatment of de Novo Native Coronary Artery Lesions

NCT00231283
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
CYPHER NxT SES ON BX SONIC OTW STENT DELIVERY SYSTEM (SDS)
Device
Lead sponsor
Cordis US Corp.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2010 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Not applicable Interventional Results available

MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT

NCT04799899
View directory record Official record
Conditions
Cardiovascular Diseases, Acute Coronary Syndrome, Depression
Interventions
Adapted MBCT, Cardiac Health Enhancement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
35 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 23, 2026, 8:43 AM EDT
Completed No phase listed Observational

Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP)

NCT04343209
View directory record Official record
Conditions
Myocardial Ischemia, Coronary Disease, Coronary Artery Disease, Heart Diseases, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases
Interventions
Myocardial Perfusion Imaging Study, AMMONIA N-13 37.5 mCi in 1 mL INTRAVENOUS INJECTION [Ammonia N 13]
Diagnostic Test · Drug
Lead sponsor
Ionetix Corporation
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
5
States / cities
Miami, Florida • Miami Beach, Florida • Jenkintown, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 23, 2026, 8:43 AM EDT
Terminated No phase listed Observational

Aortic Wall and Left Ventricular Mechanics: Echocardiographic and Hemodynamic Analysis

NCT01236313
View directory record Official record
Conditions
Coronary Disease, Cardiac Valve Disease
Interventions
TEE report
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Not applicable Interventional

Correlation Study of Imaging Data Acquired During CABG With Data Acquired in the Cath Lab

NCT02138305
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
ComboMap XT Guidewire, 'SPY' NIRF During CABG
Device · Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 23, 2026, 8:43 AM EDT
Completed No phase listed Observational

MyoStrain CMR Testing of Ischemia With Low Levels of Stress

NCT03543241
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Ischemia, Myocardial Dysfunction
Interventions
MyoStrain
Diagnostic Test
Lead sponsor
Myocardial Solutions
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety of a Single Escalating Dose of ACRX-100 in Adults With Ischemic Heart Failure

NCT01082094
View directory record Official record
Conditions
Heart Failure
Interventions
ACRX-100
Biological
Lead sponsor
Juventas Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Birmingham, Alabama • Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 6, 2012 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

NCT05908331
View directory record Official record
Conditions
In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease
Interventions
Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA)
Device
Lead sponsor
Concept Medical Inc.
Industry
Eligibility
18 Years to 110 Years
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
27
States / cities
Birmingham, Alabama • Gilbert, Arizona • Los Angeles, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 23, 2026, 8:43 AM EDT
Completed No phase listed Observational

PARA-HEART Pilot Implementation

NCT02709135
View directory record Official record
Conditions
Acute Coronary Syndrome, Chest Pain
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 3 Interventional Results available

EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)

NCT04509674
View directory record Official record
Conditions
Myocardial Infarction
Interventions
Empagliflozin, Placebo
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
6,522 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
85
States / cities
Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 75 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 23, 2026, 8:43 AM EDT
Completed No phase listed Observational Results available

Observational Study of OCT in a Patients Undergoing FFR

NCT01663896
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
OCT stent guidance
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
15
States / cities
Birmingham, Alabama • La Jolla, California • Orlando, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT06112418
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Interventions
The Cleerly CAD Staging System
Device
Lead sponsor
Cleerly, Inc.
Industry
Eligibility
55 Years and older
Enrollment
7,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
125
States / cities
Chandler, Arizona • Scottsdale, Arizona • Sun City, Arizona + 100 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

NCT03581318
View directory record Official record
Conditions
Normal and Abnormal Cardiovascular Physiology
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
7 Years to 100 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 8:43 AM EDT
Terminated No phase listed Observational Results available

Contrast Volume Reduction During PCI With the Use of a New Assisting Software Package

NCT02927990
View directory record Official record
Conditions
Coronary Stenosis, Coronary Occlusion
Interventions
Percutaneous Coronary Intervention
Other
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 23, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

ASCVD Management Using CCTA in Prostate Cancer Patients on ADT

NCT05879913
View directory record Official record
Conditions
Prostate Cancer
Interventions
Coronary CT Angiography (CCTA)
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Not applicable Interventional

Catheter-Based Treatment of Cardiovascular Disease

NCT00380016
View directory record Official record
Conditions
Obstructive Coronary Artery Disease, Obstructive Peripheral Artery Disease, Structural Heart Disease
Interventions
Percutaneous Transluminal Angioplasty
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 3 Interventional

Study of the PAS-Port® Proximal Anastomosis System in Coronary Bypass Surgery

NCT00355563
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
PAS-Port Automated Proximal Anastomosis System
Device
Lead sponsor
Cardica, Inc
Industry
Eligibility
50 Years to 85 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 9, 2009 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Not applicable Interventional

Exercise Prescription in Cardiac Rehabilitation

NCT03925493
View directory record Official record
Conditions
Percutaneous Coronary Intervention, Myocardial Infarction, Coronary Artery Bypass Graft
Interventions
Graded Exercise Stress test (GXT) with Target Heart Rate Range, Heart rate monitors
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 4 Interventional Results available

Effect of Prasugrel Versus Clopidogrel on Platelet Function After Bivalirudin Cessation

NCT01789814
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Prasugrel, Clopidogrel
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 23, 2026, 8:43 AM EDT
Completed Phase 4 Interventional Results available

Platelet Inhibition With Cangrelor and Crushed Ticagrelor in STEMI

NCT03247738
View directory record Official record
Conditions
ST Segment Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Interventions
Cangrelor, Placebo
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Oct 23, 2026, 8:43 AM EDT