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ClinicalTrials.gov public records Last synced Oct 22, 2026, 8:06 AM EDT

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Showing 25–48 of 113 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Output Clear all
Terminated No phase listed Observational

Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation

NCT00920569
View directory record Official record
Conditions
Recirculation, Oxygenator Blood Volume, Cardiac Output, Venoarterial Extracorporeal Membrane Oxygenation, Venovenous Extracorporeal Membrane Oxygenation
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 27, 2016 · Synced Oct 22, 2026, 8:06 AM EDT
Terminated Phase 2 Interventional Results available

Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia

NCT00588146
View directory record Official record
Conditions
Anemia, Liver Disease, Hypoxemia
Interventions
Pegylated Interferon Alpha2b, Standard care
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2013 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational

Predicting Volume Response Study

NCT01656954
View directory record Official record
Conditions
Shock, Hypovolemia
Interventions
Passive Leg Raise (PLR)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 22, 2026, 8:06 AM EDT
Withdrawn Not applicable Interventional

Non-Invasive Measurement of Cardiac Output and Stroke Volume in PE

NCT04855370
View directory record Official record
Conditions
Pulmonary Embolism, Pulmonary Embolus/Emboli, Pulmonary Disease, Pulmonary Embolism and Thrombosis, Pulmonary Embolism Subacute Massive, Pulmonary Embolism Acute Massive
Interventions
Non-invasive hemodynamic measurements
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 22, 2026, 8:06 AM EDT
Completed Not applicable Interventional

Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock

NCT05630716
View directory record Official record
Conditions
Sepsis, Hypotension, Septic Shock
Interventions
NICOM
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 22, 2026, 8:06 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of the UltraTrac System as a Non-Invasive Monitor of Hemodynamic Parameters

NCT07862608
View directory record Official record
Conditions
Hemodynamic Monitoring
Interventions
Noninvasive Hemodynamic Monitoring System
Device
Lead sponsor
AcQumen Medical, Inc.
Industry
Eligibility
2 Months to 95 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Riverside, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 22, 2026, 8:06 AM EDT
Recruiting No phase listed Observational

The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)

NCT06895603
View directory record Official record
Conditions
ICU, Pulmonary Artery Catheter (PAC), Swan-Ganz Catheter
Interventions
Philips Advanced Monitoring Cuff (AMC)
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 8:06 AM EDT
Terminated Phase 4 Interventional Results available

The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study

NCT02253394
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Ambrisentan plus Spironolactone, Ambrisentan plus Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational

Accurate Measurement of Cardiac Output Using the Ultrasound Dilution Technique

NCT00851422
View directory record Official record
Conditions
Cardiac Output
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 18 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Oct 22, 2026, 8:06 AM EDT
Not listed Not applicable Interventional

Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning

NCT06418022
View directory record Official record
Conditions
Shock, Fluid Overload, Cardiac Output, Low
Interventions
Trendelenburg positioning VTI
Device
Lead sponsor
Lenox Hill Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 22, 2026, 8:06 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Cardiac Output Estimation Based on Pulse Wave Transit Time

NCT01877941
View directory record Official record
Conditions
Myocardial Infarction, Myocardial Ischemia
Interventions
Pulmonary Artery Catheter (PAC), Endotracheal Cardiac Output Monitor (ECOM), Estimated Continuous Cardiac Output (esCCO)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
19 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Francisco, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 1, 2015 · Synced Oct 22, 2026, 8:06 AM EDT
Terminated No phase listed Observational

Endotracheal Cardiac Output Monitor (ECOM) for Patients Undergoing Liver Transplantation

NCT01299441
View directory record Official record
Conditions
Liver Transplantation
Interventions
ECOM ETT
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2017 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Invasive Cardiac Output Monitor in Children

NCT03869606
View directory record Official record
Conditions
Cardiac Output, Low, Pediatric
Interventions
NICOM by Cheetah Medical
Device
Lead sponsor
Indiana University
Other
Eligibility
11 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 22, 2026, 8:06 AM EDT
Not listed No phase listed Observational

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness

NCT06390423
View directory record Official record
Conditions
Fluid Responsiveness
Interventions
Passive leg raise, SVI via bioreactance, Echo based VTI
Diagnostic Test
Lead sponsor
CentraCare
Other
Eligibility
30 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Saint Cloud, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational

Hemodynamic Measurements During Liver Transplantation

NCT00682110
View directory record Official record
Conditions
Liver Transplantation
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 1, 2010 · Synced Oct 22, 2026, 8:06 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

NCT04755764
View directory record Official record
Conditions
Systolic Hypertension, Pregnancy Related, Diastolic Hypertension, Cardiac Output, Low, Cardiac Output, High
Interventions
Labetalol, Atenolol, Nifedipine
Drug
Lead sponsor
Marshall University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 22, 2026, 8:06 AM EDT
Withdrawn Not applicable Interventional

Impedance During Cardiac Catheterization to Build a Non-Invasive Cardiac Output Algorithm

NCT06171698
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Research Prototype Monitor
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets

NCT00027157
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing Effects of Lateral Tilt on Cardiac Output Using a Non-invasive Technique

NCT04112719
View directory record Official record
Conditions
Cardiac Output
Interventions
supine position, 15 degrees lateral tilt, 30 degrees lateral tilt
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 22, 2026, 8:06 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Global and Regional Myocardial Strain and Power Output In Patients With Single Ventricles Using Novel MRI Techniques

NCT01107990
View directory record Official record
Conditions
Fontan Procedure, Hypoplastic Left Heart Syndrome, Tricuspid Atresia, Double Inlet Left Ventricle
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 22, 2026, 8:06 AM EDT
Completed No phase listed Observational

Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)

NCT01613859
View directory record Official record
Conditions
Intensive Care
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 21 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2016 · Synced Oct 22, 2026, 8:06 AM EDT
Terminated No phase listed Observational

The Nanowear Wearable System SimpleSense Validation Trial for Cardiac Output

NCT05629533
View directory record Official record
Conditions
Right Heart Catheterization
Interventions
SimpleSense
Device
Lead sponsor
Nanowear Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 22, 2026, 8:06 AM EDT
Completed Phase 3 Interventional Results available

Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass

NCT02025621
View directory record Official record
Conditions
Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
Interventions
Levosimendan, Placebo
Drug
Lead sponsor
Tenax Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
882 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
49
States / cities
Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2018 · Synced Oct 22, 2026, 8:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics

NCT01139294
View directory record Official record
Conditions
Dehydration, Cardiac Output, Pediatrics
Interventions
Hylenex
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Months to 3 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2018 · Synced Oct 22, 2026, 8:06 AM EDT