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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Valve Annuloplasty Clear all
Terminated Not applicable Interventional Results available

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)

NCT03016975
View directory record Official record
Conditions
Functional Mitral Regurgitation, Mitral Regurgitation, Mitral Insufficiency
Interventions
Edwards Cardioband System, Guideline Directed Medical Therapy
Device · Drug
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
24
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Jul 23, 2026, 10:46 PM EDT
Recruiting Not applicable Interventional

AMEND TS Early Feasibility Study

NCT06951672
View directory record Official record
Conditions
Symptomatic Functional MR 3 or Greater
Interventions
This study will evaluate the safety and functionality of the AMEND™ Trans-Septal System for annuloplasty as a therapy for mitral regurgitation.
Device
Lead sponsor
Valcare Medical Ltd.
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
11
States / cities
Phoenix, Arizona • La Jolla, California • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 23, 2026, 10:46 PM EDT
Not listed No phase listed Observational

Primary Mitral Regurgitation Repair

NCT04067635
View directory record Official record
Conditions
Mitral Valve Insufficiency, Mitral Valve Prolapse, Chronic Mitral Disease, Mitral Regurgitation, Mitral Valve Disease, Degenerative Mitral Valve Disease, Myxomatous Mitral Valve Degeneration, Ventricular Remodeling
Interventions
Not listed
Lead sponsor
Eric Y. Yang, MD PhD
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 23, 2026, 10:46 PM EDT
Completed No phase listed Observational Results available

Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial

NCT01585779
View directory record Official record
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency
Interventions
Contour 3D® implant for tricuspid valve repair, Tri-Ad® implant for tricuspid valve repair
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Aventura, Florida • Ann Arbor, Michigan • Asheville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Jul 23, 2026, 10:46 PM EDT
Suspended Not applicable Interventional

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

NCT06479824
View directory record Official record
Conditions
Tricuspid Valve Insufficiency
Interventions
TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty)
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Atlanta, Georgia • Roslyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jul 23, 2026, 10:46 PM EDT
Not listed No phase listed Observational

Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery

NCT04785885
View directory record Official record
Conditions
Transcatheter Aortic Valve Replacement, Cardiac Valve Annuloplasty
Interventions
iStat Handheld Blood Analyzer, Hemochron
Diagnostic Test
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 23, 2026, 10:46 PM EDT
Completed Not applicable Interventional

Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation

NCT01246947
View directory record Official record
Conditions
Cardiac Surgery, Tricuspid Valve Regurgitation
Interventions
Tricuspid valve repair, Mitral surgery alone
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Jul 23, 2026, 10:46 PM EDT
Active, not recruiting No phase listed Observational

Paired-Ring Mitral Annuloplasty Ring Sizing Device

NCT06965725
View directory record Official record
Conditions
Heart Valve Diseases
Interventions
Annuloplasy ring sizing device
Device
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Glenview, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 23, 2026, 10:46 PM EDT
Withdrawn Not applicable Interventional

Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy

NCT00428103
View directory record Official record
Conditions
Mitral Valve Regurgitation, Congestive Heart Failure, Cardiomyopathy
Interventions
3 dimensional echocardiography
Procedure
Lead sponsor
Juan Crestanello, MD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2013 · Synced Jul 23, 2026, 10:46 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair

NCT00567853
View directory record Official record
Conditions
Mitral Valve Regurgitation
Interventions
Implantation of the MEMO 3D Annuloplasty Ring
Device
Lead sponsor
Sorin Group USA, Inc.
Industry
Eligibility
18 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
Minneapolis, Minnesota • St Louis, Missouri • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Jul 23, 2026, 10:46 PM EDT
Completed Not applicable Interventional

Mitral Loop Cerclage(MLC) for Reducing Functional Mitral Regurgitation

NCT02471664
View directory record Official record
Conditions
Functional Mitral Regurgitation, Heart Failure
Interventions
Mitral Loop Cerclage Annuloplasty
Device
Lead sponsor
Tau-MEDICAL Co., Ltd.
Industry
Eligibility
20 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Jul 23, 2026, 10:46 PM EDT
Recruiting Not applicable Interventional

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

NCT03142152
View directory record Official record
Conditions
Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
Interventions
Carillon Mitral Contour System, Guideline Directed Heart Failure Medication
Device · Other
Lead sponsor
Cardiac Dimensions, Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
75
States / cities
Gilbert, Arizona • Phoenix, Arizona • Tucson, Arizona + 61 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 23, 2026, 10:46 PM EDT
Not listed Not applicable Interventional

Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Also Known as TriAlign™.

NCT02574650
View directory record Official record
Conditions
Chronic Symptomatic Functional Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Heart Valve Disease
Interventions
Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS)
Device
Lead sponsor
Mitralign, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Jul 23, 2026, 10:46 PM EDT
Recruiting Not applicable Interventional

Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System

NCT04890821
View directory record Official record
Conditions
Tricuspid Regurgitation Functional
Interventions
CI Percutaneous Ring Annuloplasty System
Device
Lead sponsor
Cardiac Implants LLC
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Jul 23, 2026, 10:46 PM EDT
Recruiting No phase listed Observational

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

NCT04761120
View directory record Official record
Conditions
Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
Interventions
Abbott SJM Rigid Saddle Ring, Abbott SJM Séguin Ring, Abbott SJM Tailor Ring, Abbott SJM Tailor Band
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
2
States / cities
Durham, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 23, 2026, 10:46 PM EDT
Terminated No phase listed Observational

HAART Annuloplasty Device Valve Repair Registry

NCT04035356
View directory record Official record
Conditions
Aortic Valve Insufficiency, Aortic Aneurysm
Interventions
Aortic valve repair
Device
Lead sponsor
Biostable Science & Engineering
Industry
Eligibility
Not listed
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
5
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 23, 2026, 10:46 PM EDT