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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiopulmonary Disease Clear all
Completed No phase listed Observational Accepts healthy volunteers

Near Infrared Spectroscopy for the Detection of Acute Kidney Injury in Children Following Cardiac Surgery

NCT01382758
View directory record Official record
Conditions
Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery, Children
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
1 Day to 4 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Phase 3 Interventional

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

NCT00088179
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
pexelizumab in conjunction with CABG
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
182
States / cities
Birmingham, Alabama • Fairhope, Alabama • Huntsville, Alabama + 129 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Phase 2 Interventional Results available

Inhaled Nitrite in Subjects With Pulmonary Hypertension

NCT01431313
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure, Diastolic
Interventions
Inhaled Nitrite
Drug
Lead sponsor
Schmidhofer, Mark, MD
Individual
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional

Seattle Cardiorenal Remote Ischemic Preconditioning Trial

NCT01260259
View directory record Official record
Conditions
Congenital Heart Disease, Cardiopulmonary Bypass, Myocardial Injury, Acute Kidney Injury, Acute Lung Injury
Interventions
RIPC, Control
Procedure
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 17, 2013 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Mannequin Study to Assess Various CPR Training Methods Using a Student Population

NCT01833910
View directory record Official record
Conditions
Cardiac Arrest, Heart Disease
Interventions
AHA CPR Anytime Video Self-Instruction Kit, AHA CPR Anytime DVD
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional

Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department

NCT02861508
View directory record Official record
Conditions
Chest Pain, Dyspnea, Syncope, Hypotension
Interventions
Point-of-care ultrasound, Usual care
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Jul 23, 2026, 9:33 AM EDT
Terminated Not applicable Interventional Results available

ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest

NCT00189423
View directory record Official record
Conditions
Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest
Interventions
Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR), Standard cardiopulmonary resuscitation (S-CPR)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
1,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
7
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Royal Oak, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of CPR Outcomes Between Traditional and Endomorphic Manikins With and Without Equipment

NCT04283214
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Cardiopulmonary Resuscitation
Other
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Phase 2 Interventional

Vitamin D3 Supplementation for Heart Failure Patients

NCT01636570
View directory record Official record
Conditions
Heart Failure, Vitamin D Deficiency, Cardiomyopathy, Congestive Heart Failure
Interventions
Placebo Comparator: Sugar Pill, Vitamin D3 (cholecalciferol)
Drug
Lead sponsor
Heidi Moretti, MS, RD
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Jul 23, 2026, 9:33 AM EDT
Completed No phase listed Observational

Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

NCT01033266
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
CPET
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Jul 23, 2026, 9:33 AM EDT
Terminated Not applicable Interventional

Brain Oxygenation Monitoring in Patients Undergoing Coronary Artery Bypass Surgery

NCT00137527
View directory record Official record
Conditions
Neurological Manifestations
Interventions
Optimizing hemodynamic and anesthetic parameters to improve cerebral perfusion
Device
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 16, 2014 · Synced Jul 23, 2026, 9:33 AM EDT
Terminated Phase 2 Interventional Results available

Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)

NCT01437878
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Interventions
Iloprost, Placebo
Drug
Lead sponsor
Actelion
Industry
Eligibility
40 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
9
States / cities
Torrance, California • Jacksonville, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Strategies to Motivate and Relieve Stress

NCT05776264
View directory record Official record
Conditions
Chronic Lung Disease, Cardiopulmonary Disease
Interventions
Music Condition, Podcast Condition
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Jul 23, 2026, 9:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cardiopulmonary Effects of Particulate Exposure

NCT00011310
View directory record Official record
Conditions
Respiratory Tract Diseases, Cardiac Diseases, Bronchitis
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2006 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Phase 2 Interventional Results available

Vardenafil Inhaled for Pulmonary Arterial Hypertension PRN Phase 2B Study

NCT04266197
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Drug: RT234 - vardenafil inhalation powder; Device: Axially Oscillating Sphere dry powder inhaler (AOS DPI)
Combination Product
Lead sponsor
Respira Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
26
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional

NEURESCUE Device as an Adjunct to In-Hospital Cardiac Arrest (ARISE)

NCT05444049
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Arrest, Cardiovascular Diseases
Interventions
NEURESCUE device
Device
Lead sponsor
neurescue
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 23, 2026, 9:33 AM EDT
Recruiting No phase listed Observational

Quality of Pediatric Resuscitation in a Multicenter Collaborative

NCT02708134
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Arrest
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 18 Years
Enrollment
7,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
40
States / cities
Los Angeles, California • Madera, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Phase 4 Interventional Results available

Platelet Transfusion During Neonatal Open Heart Surgery

NCT03045068
View directory record Official record
Conditions
Cardiac Disease, Cardiac Surgery, Cardiopulmonary Bypass, Platelet Transfusion, Arrythmia, Cardiac, Mortality
Interventions
Platelet Transfusion, FFP and Cryoprecipitate, PRBC and cell saver Transfusion, Factor Concentrate (Bebulin)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Day to 3 Months
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional Results available

Cerebral Autoregulation Monitoring During Cardiac Surgery

NCT00981474
View directory record Official record
Conditions
Thoracic Surgery, Cardiopulmonary Bypass
Interventions
blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
Drug · Device
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 23, 2026, 9:33 AM EDT
Terminated Phase 2 Interventional Results available

Vitamin B12a Vasoplegic Syndrome

NCT03735316
View directory record Official record
Conditions
Vasoplegic Syndrome
Interventions
Hydroxocobalamin, Cardiopulmonary Bypass, Placebos
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 23, 2026, 9:33 AM EDT
Completed Not applicable Interventional

Feasibility of Exercise With Post-Op Lung Cancer Patients

NCT00636571
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Exercise
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2013 · Synced Jul 23, 2026, 9:33 AM EDT
Completed No phase listed Observational Results available

Cardio-pulmonary Rehabilitation and Sleep Quality

NCT04668599
View directory record Official record
Conditions
Obstructive Pulmonary Disease, Cardiomyopathies, Heart Failure, Restrictive Lung Disease
Interventions
Cardiopulmonary rehabilitation
Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Jul 23, 2026, 9:33 AM EDT
Active, not recruiting Phase 4 Interventional

A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients

NCT04508907
View directory record Official record
Conditions
Hepatitis C, Kidney Transplant; Complications, Heart Transplant Infection
Interventions
Mavyret
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 23, 2026, 9:33 AM EDT
Terminated Phase 3 Interventional

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

NCT05253209
View directory record Official record
Conditions
Ventricular Septal Defect, Atrioventricular Septal Defect, Primum Atrial Septal Defect
Interventions
L-citrulline, Plasmalyte A
Drug
Lead sponsor
Asklepion Pharmaceuticals, LLC
Industry
Eligibility
Up to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
10
States / cities
Birmingham, Alabama • Aurora, Colorado • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 9:33 AM EDT