- Conditions
- Osteoarthritis, Knee
- Interventions
- Naproxen 500 Mg, Placebo
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 721–744
of 914
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis, Knee
- Interventions
- Celecoxib, Placebo
- Drug · Other
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 388 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2004
- U.S. locations
- 33
- States / cities
- Birmingham, Alabama • Buena Park, California • Denver, Colorado + 28 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Total Knee Arthroplasty using Manual Instrumentation, Total Knee Arthroplasty using Robotic Arm
- Device
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 4
- States / cities
- Athens, Georgia • Egg Harbor, New Jersey • Cleveland, Ohio + 1 more
- Conditions
- Osteoarthritis
- Interventions
- Diclofenac Topical Sodium Gel 1%
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 35 Years and older
- Enrollment
- 480 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- Parsippany, New Jersey
- Conditions
- Pain, Arthrofibrosis, Osteoarthritis, Knee
- Interventions
- Hydrocortisone, Dextrose 5% in water (D5W)
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 83 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Osteoarthritis, Arthroplasty, Replacement, Knee
- Interventions
- Educational program to address patients' expectations
- Behavioral
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 146 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2004
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis of Knee
- Interventions
- MM-II dose I, MM-II dose II, MM-II dose III, Placebo
- Drug
- Lead sponsor
- Sun Pharmaceutical Industries Limited
- Industry
- Eligibility
- 40 Years to 99 Years
- Enrollment
- 397 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Tempe, Arizona • Riverside, California + 15 more
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- Chestnut Hill, Massachusetts
- Conditions
- Osteoarthritis
- Interventions
- ABT-981, Placebo
- Biological
- Lead sponsor
- AbbVie (prior sponsor, Abbott)
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Osteoarthritis, Knee
- Interventions
- Amniotic Fluid, Saline Placebo
- Other
- Lead sponsor
- MiMedx Group, Inc.
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 4
- States / cities
- Birmingham, Alabama • Atlanta, Georgia • Des Plaines, Illinois + 1 more
- Conditions
- Degenerative Arthritis
- Interventions
- Orthosensor™ VERASENSE™ Knee System
- Device
- Lead sponsor
- LifeBridge Health
- Other
- Eligibility
- 45 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Lidoderm (Lidocaine 5% Patch), Placebo Patch
- Drug
- Lead sponsor
- Endo USA Inc., a Keenova Therapeutics Company
- Industry
- Eligibility
- 37 Years and older
- Enrollment
- 169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 20
- States / cities
- Paradise Valley, Arizona • Phoenix, Arizona • Milford, Connecticut + 16 more
- Conditions
- Osteoarthritis
- Interventions
- Meloxicam Test Capsules, Placebo Capsules
- Drug
- Lead sponsor
- Iroko Pharmaceuticals, LLC
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 403 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 40
- States / cities
- Birmingham, Alabama • Carmichael, California • Pismo Beach, California + 31 more
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 4
- States / cities
- La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Lidocaine Hydrochloride
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Pain, Postoperative, Arthroplasty, Replacement, Knee, Osteoarthritis
- Interventions
- Liposomal bupivacaine, bupivacaine HCl, morphine, epinephrine, methylprednisolone
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa
- Conditions
- Osteoarthritis, Knee
- Interventions
- PF-04191834, PF-04191834 placebo, Naproxen placebo, Naproxen
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 190 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 25
- States / cities
- Peoria, Arizona • Phoenix, Arizona • Anaheim, California + 20 more
- Conditions
- Osteoarthritis Pain
- Interventions
- ACP-044 Dose A, ACP-044 Dose B, Placebo
- Drug
- Lead sponsor
- ACADIA Pharmaceuticals Inc.
- Industry
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 34
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • La Mesa, California + 28 more
- Conditions
- Osteoarthritis
- Interventions
- RTX-GRT7039
- Drug
- Lead sponsor
- Grünenthal GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 714 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 27
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Anaheim, California + 24 more
- Conditions
- Osteoarthritis
- Interventions
- Tranexamic Acid (TXA), ε-Aminocaproic Acid (EACA)
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa
- Conditions
- Osteoarthritis
- Interventions
- Buprenorphine transdermal patch, Placebo
- Drug
- Lead sponsor
- Purdue Pharma LP
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 529 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2004
- U.S. locations
- 44
- States / cities
- Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 38 more
- Conditions
- Osteoarthritis Knee Pain
- Interventions
- Duloxetine, Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 524 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 32
- States / cities
- Tucson, Arizona • Garden Grove, California • Long Beach, California + 29 more
- Conditions
- Knee Osteoarthritis
- Interventions
- 99mTc-EC20
- Drug
- Lead sponsor
- Virginia Kraus
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Osteoarthritis, Knee
- Interventions
- dynamic contrast enhanced MRI, geniculate artery embolization
- Diagnostic Test · Procedure
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 25 Years to 90 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina