Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 4:49 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 4,841 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Postoperative Pain
Interventions: Not listed
Lead sponsor: Senthil Sadhasivam; Other
Eligibility: 3 Years to 15 Years
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depressive Disorder, Depression
Interventions: REL-1017, Placebo; Drug
Lead sponsor: Levomecor Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 70
States / cities: Homewood, Alabama • Chandler, Arizona • Phoenix, Arizona + 59 more

Conditions: Anxiety Disorders and Symptoms, Depression, Bipolar Disorder, Symptoms
Interventions: Personalized MAYA Mobile App, General MAYA Mobile App; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Dementia, Mild Cognitive Impairment
Interventions: Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI), Neuropsychological Data, Clinical Scales; Behavioral
Lead sponsor: Centre for Addiction and Mental Health; Other
Eligibility: 60 Years and older
Enrollment: 506 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 4
States / cities: Los Angeles, California • St Louis, Missouri • New York, New York + 1 more

Conditions: Depression, Anxiety
Interventions: DISC-MA; Device
Lead sponsor: Woebot Health; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 203 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anxiety, Depression, Psychological Stress, Psychological Distress, Well-being
Interventions: Healthy Minds Program Foundations Training; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 698 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Seasonal Affective Disorder
Interventions: Litebook treatment devices, Inactivated negative ion generator; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Anxiety Generalized, Quality of Life, Depression
Interventions: PISCES; Behavioral
Lead sponsor: George Demiris, PhD; Other
Eligibility: 18 Years and older
Enrollment: 523 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression
Interventions: Prevention Intervention Project, Psychoeducation; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 14 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depressive Disorder
Interventions: memantine, Placebo; Drug
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 85 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Childhood Cancers
Interventions: Behavioral intervention sessions, CD-ROM, DVD and pamphlet, Respite care; Behavioral · Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 212 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 5
States / cities: Los Angeles, California • Atlanta, Georgia • New Brunswick, New Jersey + 1 more

Conditions: Depression, Cannabis Use Disorder, HIV
Interventions: MRI Study; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 59 Years
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Major Depressive Disorder, Depression
Interventions: REL-1017, Placebo; Drug
Lead sponsor: Levomecor Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 36
States / cities: Dothan, Alabama • Homewood, Alabama • Anaheim, California + 32 more

Conditions: Depression
Interventions: Culturally Congruent Assessment and Treatment; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 80 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: PostPartum Depression
Interventions: MamaLift Plus, Digital Sham App; Device
Lead sponsor: Healthcare Innovation Technology Lab; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Perinatal Depression, Chronic Pain
Interventions: No intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hematopoietic Stem Cell Transplant
Interventions: Ayo wearable; Device
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 8 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Treatment-resistant Bipolar Depression
Interventions: Allogeneic Bone Marrow Derived Multipotent Mesenchymal Stromal Cells (MSCs), Placebo; Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Heart Failure, Congestive
Interventions: Interpersonal and behavioral psychotherapy, Attention control (AC) condition; Behavioral
Lead sponsor: University of Iowa; Other
Eligibility: 55 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Treatment Resistant Depression
Interventions: Direct Neural Electrical Stimulation; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 22 Months to 70 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alcohol Dependence, Bipolar Disorder
Interventions: Acamprosate; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Postpartum Depression, Postpartum Anxiety, Parenting Stress, Parent Child Relationships
Interventions: Connecting and Reflecting Experience (CARE) Program; Behavioral
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Depression - Major Depressive Disorder
Interventions: transcutaneous spinal direct current stimulation; Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 60 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Depression, Mood, Sleep, Physical Activity
Interventions: Intern Health Study behavioral change mobile notification; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 2,562 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

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Personalizing Perioperative Analgesia in Children

A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

Personalized Mobile Cognitive Behavioral Therapy Application

Longitudinal Observational Biomarker Study

Potency and Precision Investigation

COVID-19 and the Healthy Minds Program for Educators

Environmental Treatment for Seasonal Affective Disorder (SAD)

A Problem Solving Intervention for Hospice Caregivers

Preventing Depression in the Children of Depressed African American Mothers

Memantine Augmentation of Antidepressants

Facilitating Parent Adaptation to Pediatric Transplant: The P-SCIP Trial

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDD

Effectiveness of Culturally Based Congruent Care in Treating Hispanics With Major Depressive Disorder

Curio Digital Therapy for the Treatment of Post-partum Depression

CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean

Light Therapy to Treat Depression in Pediatric Stem Cell Therapy Recipients

Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression

Interpersonal Psychotherapy for Depression in People With Heart Failure

Deciphering Principles of Network Dynamics Underlying Depression Symptom Severity From Multi-day Intracranial Recordings in Patients With Major Depression

Open Label Trial of Acamprosate in Bipolar Alcoholics

A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program

Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains

Intern Health Study 2022 and 2023