Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2713–2736 of 10,824 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Developmental Defect Clear all

Conditions: Cystic Fibrosis Related Bone Disease
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 6 Years to 75 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Kidney Calculi
Interventions: Potassium Citrate, Acetazolamide, Diet low in oxalate and purines; Drug · Behavioral
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 5 Years to 17 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Sickle Cell Disease
Interventions: High Demand / Low Infusion, PCA Dosing Plan; Other
Lead sponsor: Carelon Research; Other
Eligibility: 10 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 28
States / cities: Oakland, California • New Haven, Connecticut • Wilmington, Delaware + 18 more

Conditions: Normal Pressure Hydrocephalus
Interventions: CSF collection; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Myotonic Dystrophy
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Duchenne Muscular Dystrophy Cardiomyopathy, Cardiomyopathy, Dilated
Interventions: Ifetroban, Placebo; Drug
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 7 Years and older · Male only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 10
States / cities: Little Rock, Arkansas • Los Angeles, California • Washington D.C., District of Columbia + 7 more

Conditions: Leukemia
Interventions: laromustine, temozolomide; Drug
Lead sponsor: Vion Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 4
States / cities: Indianapolis, Indiana • Durham, North Carolina • Cleveland, Ohio

Conditions: Homocystinuria
Interventions: Pegtibatinase, Placebo; Drug
Lead sponsor: Travere Therapeutics, Inc.; Industry
Eligibility: 5 Years to 65 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 10
States / cities: Aurora, Colorado • Miami, Florida • Chicago, Illinois + 6 more

Conditions: Cutis Laxa
Interventions: Not listed
Lead sponsor: Wake Forest University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Osteochondrodysplasia
Interventions: SAR442501, Placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Muscular Dystrophies
Interventions: Drisapersen; Drug
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 5 Years and older · Male only
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 10
States / cities: Sacramento, California • Tampa, Florida • Iowa City, Iowa + 7 more

Conditions: Myelomeningocele, Spina Bifida
Interventions: Transcutaneous stimulation; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 5 Years to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Familial Hypercholesterolemia, Cholesterol, Elevated, Genetic Disease
Interventions: Motivational interview (MI); Behavioral
Lead sponsor: Essentia Health; Other
Eligibility: 2 Years to 75 Years
Enrollment: 257 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Duluth, Minnesota

Conditions: Pruritus, Atopic Dermatitis
Interventions: difelikefalin 0.25 mg, difelikefalin 0.5 mg, TCS Cream, Placebo, Vehicle Cream; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 287 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 61
States / cities: Scottsdale, Arizona • Fort Smith, Arkansas • Rogers, Arkansas + 56 more

Conditions: Rett Syndrome
Interventions: Trofinetide; Drug
Lead sponsor: ACADIA Pharmaceuticals Inc.; Industry
Eligibility: 2 Years to 5 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 7
States / cities: Birmingham, Alabama • Aurora, Colorado • Chicago, Illinois + 4 more

Conditions: Infant, Premature, Diseases, Brain White Matter Disease Periventricular
Interventions: SPEEDI Intervention; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: Up to 18 Weeks
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Infant, Premature, Diseases, Infant, Small for Gestational Age
Interventions: Individualized Nutrition, Optimized nutrition; Dietary Supplement
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Up to 7 Days
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Healthy, Muscular Dystrophy, Retinal Degeneration, Skin Diseases, Virus Diseases
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 1978 – 2000
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Dementia, Alzheimer's Disease, Parkinson Disease, Huntington Disease
Interventions: Not listed
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cystic Fibrosis
Interventions: Not listed
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 90 Years
Enrollment: 140 participants
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Bloating
Interventions: OPTI-BIOME™ Bacillus subtilis MB40, Placebo; Dietary Supplement · Other
Lead sponsor: BIO-CAT Microbials, LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Foothill Ranch, California • Orlando, Florida

Conditions: Major Depression, Mania, Anxiety Disorders, Psychotic Disorder, Alcohol Dependence, Drug Dependence, Eating Disorders, Suicidality, Dysthymia, ADHD, Tourettes Disorder, Conduct Disorder, Oppositional Defiant Disorder, Pervasive Developmental Disorder
Interventions: MINI-KID; Other
Lead sponsor: University of South Florida; Other
Eligibility: 6 Years to 17 Years
Enrollment: 230 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Dysferlinopathy
Interventions: rAAVrh74.MHCK7.DYSF.DV; Drug
Lead sponsor: Sarepta Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Factor IX Deficiency
Interventions: Standard care with blood and urine sample collection; Other
Lead sponsor: Skane University Hospital; Other
Eligibility: Not listed
Enrollment: 550 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Search by objective public record fields.

Cystic Fibrosis Related Bone Disease: the Role of CFTR

Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones

THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)

Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus

Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy

Temozolomide and VNP40101M in Treating Patients With Relapsed or Refractory Leukemias

Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)

Structural Analysis of Human Tissue

A First-in-human Single and Repeated Dose Escalation Study of SAR442501 in Healthy Adults Subjects

A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects

Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida

Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome

Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention

Optimizing Individual Nutrition in Preterm Very Low Birth Weight Infants

Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers

Memory Disorders Registry

Patient Outcomes of Clinic Transition From Face to Face Encounter to Telemedicine in Cystic Fibrosis

A Study to Evaluate OPTI-BIOME™ Bacillus Subtilis MB40 on Abdominal Discomfort, Gas and Bloating in a Healthy Population

Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

rAAVrh74.MHCK7.DYSF.DV for Treatment of Dysferlinopathies

Natural History Study of Factor IX Treatment and Complications