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ClinicalTrials.gov public records Last synced Sep 26, 2026, 3:27 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Diabetic Complications Clear all
Recruiting Phase 3 Interventional

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

NCT06217302
View directory record Official record
Conditions
Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
Interventions
Sotagliflozin, Placebo
Drug
Lead sponsor
Alessandro Doria
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
13
States / cities
Stanford, California • Aurora, Colorado • Orlando, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Not applicable Interventional Results available

Instant Total Contact Cast to Heal Diabetic Foot Ulcers

NCT01221207
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Total Contact Cast, Instant Total Contact Cast (ITCC), Removable Cast Walker (RCW)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Tucson, Arizona • Dallas, Texas • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2020 · Synced Sep 26, 2026, 3:27 AM EDT
Terminated Not applicable Interventional

Amnio-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

NCT06572839
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Amnio-Maxx
Other
Lead sponsor
Capsicure, LLC
Network
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
12
States / cities
Athens, Alabama • San Diego, California • Coral Gables, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 26, 2026, 3:27 AM EDT
Completed No phase listed Observational

Assessment of EyeArt Performance With Retinal Imaging Devices

NCT04302012
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
Color fundus photography, Mydriatic Agent
Procedure · Drug
Lead sponsor
Eyenuk, Inc.
Industry
Eligibility
22 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Sep 26, 2026, 3:27 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Safety Study of Topical Human FGF-1 for Wound Healing

NCT00916292
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
FGF-1 141
Drug
Lead sponsor
Phage Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 11, 2012 · Synced Sep 26, 2026, 3:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot

NCT01951859
View directory record Official record
Conditions
Diabetic Neuropathy
Interventions
Neuropathy/Ulcer Homeopathic topical cream
Other
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Sep 26, 2026, 3:27 AM EDT
Recruiting Not applicable Interventional

A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.

NCT05588583
View directory record Official record
Conditions
Wounds, Wound of Skin, Wound Leg, Wound; Foot, Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
Mepilex Up
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Castro Valley, California • Los Angeles, California • Miami, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Sep 26, 2026, 3:27 AM EDT
Withdrawn Not applicable Interventional

Mobile Application to Enhance Diabetic Care

NCT01983917
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Diabetes Mobile Application
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Phase 2 Interventional Results available

Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema

NCT03126786
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
IVT aflibercept, Sham SC, SC CLS-TA
Drug
Lead sponsor
Clearside Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
29
States / cities
Phoenix, Arizona • Tucson, Arizona • Bakersfield, California + 25 more
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Sep 26, 2026, 3:27 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of the Noxsano Wound Care Bandage

NCT04123093
View directory record Official record
Conditions
Wound Heal, Peripheral Artery Disease, Ulcer, Leg, Ulcer Foot, Diabetic Foot Ulcer, Arterial Insufficiency
Interventions
Noxsano Bandage (Healthy Volunteers), Noxsano Bandage (Wound Care)
Device
Lead sponsor
OhioHealth
Other
Eligibility
18 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Sep 26, 2026, 3:27 AM EDT
Withdrawn Phase 2 Interventional

A Study of CGRP Monoclonal Antibody to Treat Diabetic Neuropathy

NCT05937152
View directory record Official record
Conditions
Diabetic Polyneuropathy
Interventions
Eptinezumab, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits

NCT04328207
View directory record Official record
Conditions
Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract, Behavior, Health
Interventions
No Financial Incentive, Financial Incentive
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Phase 1 Interventional

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

NCT03835884
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Interventions
AR-13503 Implant 10.6 Dose, AR-13503 Implant 21.2 Dose, AR-13503 42.4 Dose, AR-13503 63.6 Dose
Drug
Lead sponsor
Aerie Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
6
States / cities
Gilbert, Arizona • Beverly Hills, California • Walnut Creek, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Sep 26, 2026, 3:27 AM EDT
Terminated Phase 3 Interventional

Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of Wagner 2 DFUs

NCT05372809
View directory record Official record
Conditions
Diabetic Foot
Interventions
SkinTE, Control
Biological · Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
13
States / cities
Fresno, California • Los Angeles, California • Hollywood, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

How Shoes With Rocker Soles Affect Walking

NCT00006438
View directory record Official record
Conditions
Diabetic Feet
Interventions
Shoes with Rocker Soles
Device
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
40 Years to 60 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 1999
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 26, 2026, 3:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Thermal Screening for Early Diabetic Peripheral Neuropathy (DPN)

NCT03069729
View directory record Official record
Conditions
Diabetic Neuropathies, Diabetic Foot, Diabetic Retinopathy
Interventions
no intervention
Other
Lead sponsor
VisionQuest Biomedical LLC
Industry
Eligibility
35 Years to 76 Years
Enrollment
331 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDN

NCT04857957
View directory record Official record
Conditions
Painful Diabetic Neuropathy
Interventions
Oral dose CNTX-6016 or oral dose Placebo
Drug
Lead sponsor
Centrexion Therapeutics
Industry
Eligibility
18 Years to 59 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Not applicable Interventional

A Nutritional Intervention for Diabetic Neuropathy

NCT01690962
View directory record Official record
Conditions
Diabetic Neuropathy
Interventions
Vegan diet and vitamin B12 supplement, Vitamin B12 supplement
Other · Dietary Supplement
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Phase 1 Interventional

This Study Tests a New Medicine Called BI 685509 in Patients That Have Kidney Problems Because of Diabetes. The Study Tests How BI 685509 is Taken up in the Body and How Well it is Tolerated (Multiple Rising Doses)

NCT03165227
View directory record Official record
Conditions
Diabetic Nephropathies
Interventions
BI 685509, Placebo
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
22
States / cities
Huntsville, Alabama • La Mesa, California • Los Gatos, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 26, 2026, 3:27 AM EDT
Completed Not applicable Interventional

Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers

NCT02209051
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers
Other
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
8
States / cities
Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2017 · Synced Sep 26, 2026, 3:27 AM EDT
Active, not recruiting Phase 2 Interventional

4D-150 in Patients With Diabetic Macular Edema

NCT05930561
View directory record Official record
Conditions
Diabetic Macular Edema, Diabetic Retinopathy
Interventions
4D-150 IVT, Aflibercept IVT
Biological
Lead sponsor
4D Molecular Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
5
States / cities
Hagerstown, Maryland • Eugene, Oregon • Erie, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 26, 2026, 3:27 AM EDT
Not yet recruiting Not applicable Interventional

Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes

NCT06763952
View directory record Official record
Conditions
Diabetic Retinopathy, Diabetes Mellitus
Interventions
AI-BRIDGE, Educational Materials
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
22 Years and older
Enrollment
6,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 26, 2026, 3:27 AM EDT
Terminated Phase 4 Interventional

TruSkin®: Study for the Treatment of Chronic Diabetic Foot Ulcers

NCT02936115
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
TruSkin®, Wound Cover
Other
Lead sponsor
Osiris Therapeutics
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
5
States / cities
Florida City, Florida • Illinois City, Illinois • Michigan, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Sep 26, 2026, 3:27 AM EDT
Not listed Not applicable Interventional

Postmarket Study to Evaluate Biovance® in Diabetic Foot Ulcers

NCT02506452
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Biovance®, Standard of Care, Diabetic Foot Ulcers
Other
Lead sponsor
Alliqua BioMedical, Inc
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
10
States / cities
Montgomery, Alabama • Phoenix, Arizona • Fresno, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Sep 26, 2026, 3:27 AM EDT