- Conditions
- Anhedonia, Major Depressive Disorder
- Interventions
- Placebo, NBI-1065846
- Drug
- Lead sponsor
- Neurocrine Biosciences
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Garden Grove, California • Lemon Grove, California + 19 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 49–72
of 88
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Mood, Anhedonia, Depression
- Interventions
- Behavioral Activation plus Savoring, Empathic Listening
- Behavioral
- Lead sponsor
- Southern Methodist University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Depression in Adolescence
- Interventions
- Sleep extension and advance, Regular sleep duration and timing
- Behavioral
- Lead sponsor
- University of Oregon
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Interventions
- ViraSafe: Treatment pushes, BRITE
- Behavioral
- Lead sponsor
- Ksana Health
- Industry
- Eligibility
- 13 Years to 24 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 3
- States / cities
- Eugene, Oregon • Pittsburgh, Pennsylvania
- Conditions
- Depression, Bipolar Disorder, Anhedonia
- Interventions
- Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care
- Behavioral
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 21 Years to 65 Years · Female only
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Depressive Disorder, Major, Anhedonia
- Interventions
- Aticaprant, Placebo
- Drug · Other
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 31
- States / cities
- Little Rock, Arkansas • Encino, California • Newport Beach, California + 26 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Prism Training
- Device
- Lead sponsor
- GrayMatters Health Ltd.
- Industry
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Providence, Rhode Island • Houston, Texas
- Conditions
- Anhedonia
- Interventions
- Transcranial Magnetic Stimulation
- Device
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Major Depressive Disorder, Anhedonia
- Interventions
- ALTO-203 25 μg, ALTO-203 75 μg, Placebo
- Drug
- Lead sponsor
- Alto Neuroscience
- Industry
- Eligibility
- 25 Years to 64 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 15
- States / cities
- Tucson, Arizona • Oceanside, California • Torrance, California + 12 more
- Conditions
- Neurobehavioral Components of Reward and Loss Valuation
- Interventions
- cognitive behavioral therapy, valuation with instruction, valuation without instruction
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 25 Years to 50 Years
- Enrollment
- 252 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Anhedonia
- Interventions
- Emotion Induction
- Behavioral
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Depressive Disorder, Major, Anhedonia
- Interventions
- Aticaprant, Placebo
- Drug · Other
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 444 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 51
- States / cities
- Birmingham, Alabama • Lafayette, California • Orange, California + 40 more
- Conditions
- Suicidal Ideation, Suicidal, Suicidal Thoughts, Digital Health Intervention, Reward Sensitivity, Anhedonia
- Interventions
- Suicide prevention treatment
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Anhedonia, Emotional Blunting
- Interventions
- Psilocybin, Placebo
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anhedonia, Stress Response, Adolescent Development
- Interventions
- Montreal Imaging Stress Task, Trier Social Stress Test for Children
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 13 Years to 15 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Depression, Anhedonia
- Interventions
- Carbidopa Levodopa, Placebo
- Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 25 Years to 55 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Major Depressive Disorder
- Interventions
- Sertraline, Bupropion
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 133 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Coronary Heart Disease, Depression
- Interventions
- Other
- Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- MDD, Anhedonia
- Interventions
- Individualized Accelerated Intermittent Theta Burst Stimulation (Ind-aiTBS), Standard Accelerated Intermittent Theta Burst Stimulation (Std-aiTBS), Sham Accelerated Intermittent Theta Burst Stimulation (Sham)
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Anhedonia
- Interventions
- Functional Magnetic Resonance Imaging, Effort-Expenditure for Rewards Task
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Major Depressive Disorder
- Interventions
- BTRX-246040 oral capsule(s), Placebo oral capsule(s)
- Drug
- Lead sponsor
- BlackThorn Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 8
- States / cities
- Cerritos, California • Garden Grove, California • Jacksonville, Florida + 5 more
- Conditions
- Depression, Psychosis, Anhedonia
- Interventions
- Transdermal Estradiol, Micronized Progesterone, Matching Placebo Patch, Raclopride C11
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 45 Years to 55 Years · Female only
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Substance Use Disorder (SUD)
- Interventions
- real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback
- Device
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Apathy, Stroke
- Interventions
- Transcranial Direct Current Stimulation
- Device
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Stony Brook, New York