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ClinicalTrials.gov public records Last synced Nov 7, 2026, 8:26 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Essential Tremor-plus Clear all

Conditions: Essential Tremor
Interventions: JZP385, Placebo; Drug · Other
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 41
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 33 more

Conditions: Essential Tremor, Multiple System Atrophy, Corticobasal Degeneration, Supranuclear Palsy, Progressive, Parkinson Disease
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 40 Years and older
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Essential Tremor
Interventions: 1-Octanol; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 21 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Upper Limb Essential Tremor (UL ET)
Interventions: BOTOX, Placebo for BOTOX; Biological · Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 36
States / cities: Hoover, Alabama • Phoenix, Arizona • Tucson, Arizona + 31 more

Conditions: Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1, REM Sleep Behavior Disorder
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Essential Tremor
Interventions: Felix NeuroAI Wristband, Sham Device; Device
Lead sponsor: Fasikl Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 8
States / cities: Phoenix, Arizona • Palo Alto, California • Boca Raton, Florida + 5 more

Conditions: Essential Tremor
Interventions: 1-Octanol; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 21 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Parkinsonian Syndromes
Interventions: 123 I - ALTROPANE®; Drug
Lead sponsor: Alseres Pharmaceuticals, Inc; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Hopkinton, Massachusetts

Conditions: Tremor
Interventions: 15 - 30, 30 - 15; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 95 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Essential Tremor
Interventions: SAGE-324, SAGE-324 Placebo; Drug
Lead sponsor: Sage Therapeutics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 27
States / cities: Phoenix, Arizona • Rogers, Arkansas • Fresno, California + 23 more

Conditions: Essential Tremor
Interventions: levetiracetam, placebo; Drug
Lead sponsor: Southern California Institute for Research and Education; Other
Eligibility: 25 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Upper Limb Essential Tremor
Interventions: AGN-151607-DP, Placebo for AGN-151607-DP; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 19
States / cities: Carlsbad, California • Fresno, California • Fullerton, California + 16 more

Conditions: Essential Tremor
Interventions: SAGE-547, Placebo; Drug
Lead sponsor: Sage Therapeutics; Industry
Eligibility: 35 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Bingham Farms, Michigan • Raleigh, North Carolina

Conditions: Essential Tremor
Interventions: 10 mg PRAX-114, 20 mg PRAX-114, and Placebo, 10 mg PRAX-114 or 20 mg PRAX-114; Drug
Lead sponsor: Praxis Precision Medicines; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 3
States / cities: Boca Raton, Florida • Farmington Hills, Michigan • Kirkland, Washington

Conditions: Essential Tremor
Interventions: SAGE-324, SAGE-324 Matched Placebo; Drug
Lead sponsor: Sage Therapeutics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 51
States / cities: Hoover, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 45 more

Conditions: Essential Tremor, Parkinson Disease
Interventions: Cala Device; Device
Lead sponsor: Cala Health, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: San Mateo, California

Conditions: Essential Tremor
Interventions: Cala TWO; Device
Lead sponsor: Cala Health, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 263 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 32
States / cities: Phoenix, Arizona • Los Angeles, California • Mountain View, California + 28 more

Conditions: Essential Tremor, Parkinson Disease
Interventions: Felix NeuroAI Wristband; Device
Lead sponsor: Fasikl Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 2
States / cities: Boca Raton, Florida • Kansas City, Kansas

Conditions: Action Tremor, Stigma, Social
Interventions: stereotactic thalamotomy with focused ultrasound; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia
Interventions: Infinity DBS System with MR Conditional labelling; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: Not listed
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 9
States / cities: Tucson, Arizona • Aurora, Colorado • Littleton, Colorado + 6 more

Conditions: Essential Tremor
Interventions: Botulinum toxin, Placebo; Drug · Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Essential Tremor, Cervical Dystonia, Focal Dystonia
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Essential Tremor
Interventions: 60 mg ulixacaltamide, Placebo; Drug
Lead sponsor: Praxis Precision Medicines; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Essential Tremor
Interventions: SAGE-217, Placebo; Drug
Lead sponsor: Biogen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 26
States / cities: Anniston, Alabama • Little Rock, Arkansas • Rogers, Arkansas + 23 more

Search by objective public record fields.

A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)

Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography.

Octanol to Treat Essential Tremor

Study of BOTOX Injections to Assess Change in Disease Symptoms in Adult Participants With Upper Limb Essential Tremor

MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.

Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor

Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor

Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremor

Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor

A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor

Efficacy of Levetiracetam in Essential Tremor

Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor

Evaluate SAGE-547 in Participants With Essential Tremor

A Clinical Trial of PRAX-114 in Participants With Essential Tremor

Study to Evaluate SAGE-324 in Participants With Essential Tremor

Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands

Prospective Study for Symptomatic Relief of ET With Cala Therapy

Pilot Study of the Felix System in Patients With Essential Tremor and Parkinson's Tremor

ET Stigma Response to Tremor Suppression

A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling

Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)

Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor

Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)

A Study to Evaluate SAGE-217 in Participants With Essential Tremor