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ClinicalTrials.gov public records Last synced Nov 14, 2026, 12:17 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 188 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fractional Clear all

Conditions: Hypertrophic Scars
Interventions: Fraxel Repair - Fractional Laser treatment; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 50 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Skin Laxity, Lipodystrophy
Interventions: Rotational fractional resection (1.5mm diameter device); Device
Lead sponsor: Recros Medica, Inc.; Industry
Eligibility: 30 Years and older
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 6
States / cities: Campbell, California • Newport Beach, California • Roseville, California + 3 more

Conditions: Coronary Artery Disease
Interventions: FFR/CFR and IVUS; Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 100 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma, Vaginal Carcinoma, Vaginal Dryness, Vulvar Carcinoma
Interventions: Laser Therapy, Questionnaire Administration, Sham Intervention; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 4
States / cities: Baltimore, Maryland • Rochester, Minnesota • Fargo, North Dakota + 1 more

Conditions: Coronary Artery Disease
Interventions: FFR-guided PCI, CABG; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Stanford, California

Conditions: Osteoporosis, Achlorhydria, GERD, Hip Fracture
Interventions: Omeprazole; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Poikiloderma of Civatte
Interventions: DEKA SmartXide C02 laser; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Scars
Interventions: Lumenis fractional carbon dioxide laser; Device
Lead sponsor: Moy-Fincher Medical Group; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Melasma
Interventions: Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine; Device · Other
Lead sponsor: UnionDerm; Other
Eligibility: 18 Years to 74 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Skin Texture, Pigmented Lesions
Interventions: Nonablative Fractional Diode Laser; Device
Lead sponsor: Candela Corporation; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Marlborough, Massachusetts

Conditions: Coronary Artery Disease
Interventions: Vessel Fractional Flow Reserve; Diagnostic Test
Lead sponsor: Erasmus Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Abdominoplasty
Interventions: Ablation and skin resurfacing, eMatrixCO2; Procedure · Device
Lead sponsor: Syneron Medical; Industry
Eligibility: 20 Years to 60 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Lichen Planus Pigmentosus
Interventions: CO2 fractional laser; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Coronary Artery Disease
Interventions: Adenosine, Contrast Media, Resting conditions; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 763 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Palo Alto, California • Oklahoma City, Oklahoma

Conditions: Wrinkles
Interventions: Laser treatment, High-intensity focused ultrasound; Procedure · Device
Lead sponsor: Northwestern University; Other
Eligibility: 35 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Coronary Disease, Coronary Stenosis
Interventions: FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent; Procedure · Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 13
States / cities: Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more

Conditions: Vaginal Laxity, Urinary Incontinence, Sexual Dysfunction
Interventions: Intragen fractional radiofrequency with NeuViVa; Device
Lead sponsor: SHERRY Thomas; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Agoura Hills, California

Conditions: Scar Prevention
Interventions: Lumenis UltraPulse single fractional CO2 laser treatment thin skin, Single fractional CO2 treatment at surgical area closure procedure on thick skin; Device
Lead sponsor: Lumenis Be Ltd.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Beverly Hills, California

Conditions: Wrinkle
Interventions: Fraxel Laser Treatment; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Left Anterior Descending Coronary Artery Stenosis
Interventions: OpSens Medical OptoWire, FFR; Device · Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: New York, New York • Roslyn, New York

Conditions: Hypertrophic Scar, Burn Scar
Interventions: Luminis ultrapulse fractional ablative carbon dioxide laser; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Unwanted Wrinkles
Interventions: PicoWayTM; Device
Lead sponsor: Syneron Medical; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 4
States / cities: Chicago, Illinois • New York, New York • Ardmore, Pennsylvania + 1 more

Conditions: Cicatrix, Dermabrasion, Coagulation, Laser
Interventions: Fractionated laser, Dermabrasion; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Edina, Minnesota

Conditions: Rhytides, Wrinkle
Interventions: Venus Viva; Device
Lead sponsor: Venus Concept; Industry
Eligibility: 22 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: San Diego, California

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Gene Expression During Surgical Scar Remodeling by Fractional Photothermolysis

CONFORM: Rotational Fractional Resection for Submental Contouring

Measurements to Assess Severity of Epicardial Stenoses

Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors

Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended

Does Omeprazole Decrease Intestinal Calcium Absorption?

The Effects of Fractional CO2 Laser on Poikiloderma of Civatte

Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser

Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma

Nonablative Fractional Diode Laser for Treatment of Skin Resurfacing and Pigmented Lesions

Fast Assessment of STenosis Severity- FASTII Study

In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue

Fractional CO2 Laser for the Treatment of Lichen Planus Pigmentosus

CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Evaluation Using Intragen Fractional Radiofrequency With NeuViVa for the Treatment of Vaginal Laxity and Urogynecology Symptoms.

Scar Prevention Using Fractional Carbon Dioxide Laser Treatment

Fractional CO2 Laser System (Fraxel Repair Laser) Intended for Treatment of Perioral Rhytides/Wrinkles

The Drift-Reduction for Improved FFR Using Fiberoptic Technology (DRIFT) Study

Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser

Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction

Laser Resurfacing Versus Dermabrasion for Scar Revision

Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles