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ClinicalTrials.gov public records Last synced Sep 9, 2026, 8:46 PM EDT

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Showing 1–24 of 114 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 4 Interventional

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

NCT00729911
View directory record Official record
Conditions
Heart Failure
Interventions
Atrial Fibrillation ablation, Amiodarone
Procedure · Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

Ventricular Tachyarrhythmia (VT) Storm, Gene Expression in Implantable Cardioverter Defibrillator (ICD) Patients With Electrical Storm

NCT00284453
View directory record Official record
Conditions
Arrhythmias
Interventions
Peripheral blood sampling
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Not applicable Interventional

Establishing a Standard for Peri-operative Implantable Cardioverter Defibrillator (ICD) Patient Education

NCT00845234
View directory record Official record
Conditions
Arrhythmia
Interventions
Intervention
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Aurora, Colorado • Lone Tree, Colorado • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2013 · Synced Sep 9, 2026, 8:46 PM EDT
Withdrawn Not applicable Interventional

Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing

NCT00585871
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
clonidine, metoprolol
Drug
Lead sponsor
James Martins
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Phase 3 Interventional

Long Term Safety of 125 mg Per Day of Oral Azimilide in Patients With Implantable Cardioverter Defibrillator (ICDs)

NCT00751738
View directory record Official record
Conditions
Arrhythmias
Interventions
azimilide dihydrochloride
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
50
States / cities
Mobile, Alabama • Little Rock, Arkansas • La Jolla, California + 43 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing

NCT04284800
View directory record Official record
Conditions
ICD
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 9, 2026, 8:46 PM EDT
Not listed No phase listed Observational

Does Lung Impedance Correlate With Changes in BNP in Stable and Acutely Decompensated Heart Failure Patients?

NCT00560339
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Southern New Jersey Cardiac Specialists
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
6
States / cities
Glendale, California • Voorhees Township, New Jersey • Roslyn, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2007 · Synced Sep 9, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)

NCT07585968
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Winston-Salem, North Carolina • Columbus, Ohio • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Not applicable Interventional

Psychoeducational Intervention for ICD Patients (PEACE)

NCT00146679
View directory record Official record
Conditions
Heart Failure, Ventricular Arrhythmias
Interventions
Psychoeducational Telephone counseling (TC), Psychoeducational Intervention by Group (SG), Usual Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
21 Years to 75 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
5
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

OptiSense™ Performance in Detecting Atrial Episodes

NCT00870324
View directory record Official record
Conditions
Tachyarrhythmias, Atrial Fibrillation
Interventions
OptiSense Lead, Tendril Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational Results available

Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices

NCT01130896
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years and older
Enrollment
1,509 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Sep 9, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional

Developing a Digital Aid to Improve ICD Decisions

NCT07084142
View directory record Official record
Conditions
Heart Failure and Reduced Ejection Fraction
Interventions
Online, patient-facing decision-making aid (app) with personalized risk information., Implantable Cardioverter Defibrillator (ICD), Online, patient-facing decision-making app without personalized risk information.
Other · Device
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Francisco, California • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 9, 2026, 8:46 PM EDT
Withdrawn No phase listed Observational

Prevalence of Atrial Delay That Would Preclude Optimization of Atrioventricular (AV) Delay in Patients With Biventricular (BiV) Device

NCT00906100
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Not applicable Interventional

Immune Response in Patients Who Have Undergone Vaccine Therapy for Stage III or Stage IV Breast Cancer That Overexpresses HER2

NCT00363012
View directory record Official record
Conditions
Breast Cancer
Interventions
HER-2/neu intracellular domain protein, flow cytometry, immunohistochemistry staining method, biopsy, Sterile water placement
Biological · Other · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Phase 4 Interventional

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications

NCT00729703
View directory record Official record
Conditions
Tachycardia
Interventions
OVATIO DR 6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
5
States / cities
Atlanta, Georgia • Decatur, Georgia • Mandeville, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Sep 9, 2026, 8:46 PM EDT
Not listed No phase listed Observational

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

NCT00005900
View directory record Official record
Conditions
I Cell Disease, Fucosidosis, Globoid Cell Leukodystrophy, Adrenoleukodystrophy, Mannosidosis, Niemann-Pick Disease, Pulmonary Complications, Mucopolysaccharidosis I, Mucopolysaccharidosis VI, Metachromatic Leukodystrophy, Gaucher's Disease, Wolman Disease
Interventions
Not listed
Lead sponsor
Fairview University Medical Center
Other
Eligibility
0 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational Results available

PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure

NCT00279955
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Cardiac Resynchronization Therapy Device
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
93
States / cities
Huntsville, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 90 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Phase 2 Interventional

Vaccine Therapy in Treating Patients Receiving Trastuzumab For HER2-Positive Stage IIIB-IV Breast Cancer

NCT00343109
View directory record Official record
Conditions
HER2-positive Breast Cancer, Male Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
Interventions
HER-2/neu intracellular domain protein, leukapheresis, laboratory biomarker analysis, sargramostim, immunologic technique, synthetic tumor-associated peptide vaccine therapy
Biological · Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

Safety of Magnetic Resonance Imaging in Patients With Pacemakers and Defibrillators

NCT02227004
View directory record Official record
Conditions
Conditions Requiring Diagnostic Evaluation
Interventions
Perform MRI in patients with pacemaker or ICD
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 100 Years
Enrollment
1,275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

Technology Dependency and Health-Related Quality of Life

NCT00022984
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Not applicable Interventional Results available

Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)

NCT00354159
View directory record Official record
Conditions
Heart Failure
Interventions
Implantable Hemodynamic Monitor (Chronicle® IHM), and IHM in combination with single chamber ICD (Chronicle ICD)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
52
States / cities
Birmingham, Alabama • La Jolla, California • Loma Linda, California + 43 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Phase 2 Interventional

Compassionate Use Study of 125 mg Per Day of Azimilide Dihydrochloride in One Patient

NCT00752596
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Azimilide 2HCl
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
Male only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 9, 2026, 8:46 PM EDT
Completed Not applicable Interventional

Biological Therapy in Treating Patients With Advanced Cancer

NCT00005956
View directory record Official record
Conditions
Breast Cancer, Gastric Cancer, Ovarian Cancer
Interventions
HER-2/neu intracellular domain protein, therapeutic autologous dendritic cells
Biological
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2014 · Synced Sep 9, 2026, 8:46 PM EDT
Completed No phase listed Observational

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial

NCT00583297
View directory record Official record
Conditions
Ventricular Tachycardia, Cardiovascular Diseases, Arrythmia, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 9, 2026, 8:46 PM EDT