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ClinicalTrials.gov public records Last synced Oct 28, 2026, 9:20 AM EDT

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Showing 1–24 of 853 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Infant, Preterm Clear all
Terminated Not applicable Interventional Results available

Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure

NCT00833365
View directory record Official record
Conditions
Patent Ductus Arteriosus, Prematurity
Interventions
Ibuprofen
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 96 Hours
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 4, 2016 · Synced Oct 28, 2026, 9:20 AM EDT
Completed No phase listed Observational

Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus

NCT03551600
View directory record Official record
Conditions
Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions
Near-infrared spectroscopy (NIRS)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
12 Days to 6 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 28, 2026, 9:20 AM EDT
Completed No phase listed Observational

Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

NCT03277768
View directory record Official record
Conditions
Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability
Interventions
Resonance Raman Spectroscopy (RRS)
Device
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Enrollment
55 participants
Timeline
2015 – 2018
U.S. locations
2
States / cities
Gainesville, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 28, 2026, 9:20 AM EDT
Recruiting Not applicable Interventional

A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants

NCT06723067
View directory record Official record
Conditions
Premature Birth
Interventions
Wearable wireless breast pump
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 2 Interventional

18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study

NCT01426698
View directory record Official record
Conditions
Developmental Delay
Interventions
delayed cord clamping
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
24 Weeks to 31 Weeks
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Not applicable Interventional

A Study to Evaluate the Safety and Tolerability of Zidovudine (ZDV) in Premature Infants Born to HIV-Positive Women.

NCT00000855
View directory record Official record
Conditions
HIV Infections
Interventions
Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Day to 5 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2000
U.S. locations
35
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 25 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Lutein and the Retinopathy of Prematurity

NCT00672230
View directory record Official record
Conditions
Lactation
Interventions
Lutein supplement
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 28, 2026, 9:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Human Milk Fortifier and Cytokine Profile

NCT00601081
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Up to 6 Months
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 2 Interventional Results available

Darbepoetin Administration to Preterm Infants

NCT00334737
View directory record Official record
Conditions
Infant, Newborn
Interventions
Darbepoetin Alfa Injection, erythropoietin alfa injection, sham injection
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
1 Hour to 49 Hours
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
3
States / cities
Denver, Colorado • Ogden, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Immediate vs. Delayed Cord Clamping in the Preterm Neonate

NCT00579839
View directory record Official record
Conditions
PreTerm Birth, PreTerm Neonate
Interventions
Delayed Cord Clamping, Immediate Cord Clamping
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 20, 2012 · Synced Oct 28, 2026, 9:20 AM EDT
Terminated Not applicable Interventional

Cord Milking Impacts Neurodevelopmental Outcomes in Very Low Birth Weight Infants

NCT02987764
View directory record Official record
Conditions
Very Low Birth Weight Infant
Interventions
cord milking
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Up to 32 Weeks
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Oct 28, 2026, 9:20 AM EDT
Terminated Not applicable Interventional Results available

High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation

NCT01270581
View directory record Official record
Conditions
Transient Tachypnea of the Newborn
Interventions
High Flow Nasal Cannula, Bubble Nasal CPAP
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Oct 28, 2026, 9:20 AM EDT
Terminated Not applicable Interventional

Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic

NCT00278928
View directory record Official record
Conditions
Hypertriglyceridemia
Interventions
Liposyn III 20% (lipid infusion), Intralipid 20% (lipid infusion)
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
2 Days to 10 Days
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants

NCT03142568
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Sildenafil, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 28, 2026, 9:20 AM EDT
Completed No phase listed Observational

Acute Kidney Injury in Premature Infants

NCT00573079
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Minute and older
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia

NCT04447989
View directory record Official record
Conditions
Bronchopulmonary Dysplasia of Newborn
Interventions
Sildenafil, Placebo
Drug
Lead sponsor
Christoph Hornik
Other
Eligibility
Up to 29 Weeks
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
25
States / cities
Little Rock, Arkansas • San Diego, California • Washington D.C., District of Columbia + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 28, 2026, 9:20 AM EDT
Recruiting Not applicable Interventional

Vancomycin Reduction Practices (VRP) in the NICU

NCT06772675
View directory record Official record
Conditions
Antibiotic Stewardship, Neonatal Sepsis, Late-Onset, Vancomycin
Interventions
External Facilitation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
13
States / cities
Modesto, California • Oakland, California • Roseville, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 28, 2026, 9:20 AM EDT
Terminated Early Phase 1 Interventional Results available

L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

NCT03542812
View directory record Official record
Conditions
Infant,Premature, Bronchopulmonary Dysplasia, Pulmonary Hypertension
Interventions
L-Citrulline
Drug
Lead sponsor
University of Utah
Other
Eligibility
14 Days to 3 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Not applicable Interventional Results available

Effects of Massage Therapy to Induce Sleep in Preterm Infants

NCT01354028
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Massage therapy
Other
Lead sponsor
University of Arkansas
Other
Eligibility
3 Days to 20 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Delayed Cord Clamping in VLBW Infants

NCT01222364
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Standard Cord Clamping, Delayed Cord Clamping
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
0 Minutes to 1 Minute
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000
U.S. locations
4
States / cities
Birmingham, Alabama • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 28, 2026, 9:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Pulmonary Hypertension Risk in Premature Infants With Bronchopulmonary Dysplasia

NCT01516398
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD), Hypertension, Pulmonary
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
Up to 30 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
2
States / cities
Mountain View, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 28, 2026, 9:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MRI in BPD Subjects

NCT03657693
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
NICU MRI, Polysomnography
Diagnostic Test
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 4 Months
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2030
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 28, 2026, 9:20 AM EDT
Terminated Not applicable Interventional

Early Versus Late Caffeine for ELBW Newborns

NCT02524249
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Apnea of Prematurity
Interventions
Caffeine, Placebo (dextrose)
Drug
Lead sponsor
Wayne State University
Other
Eligibility
Up to 4 Weeks
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 28, 2026, 9:20 AM EDT
Completed Phase 4 Interventional

Safety of Manganese Restriction in Neonatal Parenteral Nutrition

NCT04259008
View directory record Official record
Conditions
Infant, Newborn, Disease
Interventions
Manganese omission, 5 mCg/kg/day manganese from "Multitrace-4 Neonatal."
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 1 Day
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 28, 2026, 9:20 AM EDT