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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Ischemic Stroke Clear all
Withdrawn Phase 2Phase 3 Interventional

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN)

NCT02180204
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Tenecteplase, Alteplase
Drug
Lead sponsor
Reza Behrouz, DO
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Jul 21, 2026, 4:22 AM EDT
Terminated Not applicable Interventional

Transnasal Induction of Normothermia for Neurogenic Fever

NCT06038513
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
Interventions
Transnasal Thermal Regulating Device
Device
Lead sponsor
CoolTech LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting No phase listed Observational

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke

NCT06292117
View directory record Official record
Conditions
Ischemic Stroke, CYP2C19 Polymorphism
Interventions
CYP2C19 Genotype
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Not applicable Interventional

Cranial Ultrasound for Prehospital ICH Diagnosis

NCT05492474
View directory record Official record
Conditions
Intracerebral Hemorrhage, Acute Ischemic Stroke
Interventions
Cranial Point of Care Ultrasound
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Not applicable Interventional Results available

Stroke and CPAP Outcome Study 3

NCT06029959
View directory record Official record
Conditions
Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions
Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention
Device · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jul 21, 2026, 4:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cerebral Autoregulation and Vasospasm in Patients With TBI

NCT02351518
View directory record Official record
Conditions
Tbi, Vasospasm, Cerebral Ischemia, Cerebral Infarct
Interventions
No intervention
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
15 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Jul 21, 2026, 4:22 AM EDT
Not yet recruiting Phase 1 Interventional

Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First Dose

NCT06801054
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
Drug
Lead sponsor
Memorial Hermann Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Not applicable Interventional

NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery

NCT02020421
View directory record Official record
Conditions
Aphasia
Interventions
rTMS, tDCS, Sham rTMS, Sham tDCS
Device
Lead sponsor
Dr. Alexander Thiel
Individual
Eligibility
50 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Not applicable Interventional Results available

Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage

NCT04027049
View directory record Official record
Conditions
Intracerebral Hemorrhage, Acute Ischemic Stroke
Interventions
Supine cycle ergometry of the lower extremities
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Phase 2 Interventional Results available

Safety of Intravenous Thrombolysis for Wake-up Stroke

NCT01183533
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Alteplase (iv t-PA)
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
3
States / cities
Birmingham, Alabama • Englewood, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Jul 21, 2026, 4:22 AM EDT
Withdrawn Phase 2 Interventional

OsciPulse D-dimer Efficacy Trial

NCT05389488
View directory record Official record
Conditions
Venous Thromboses, Ischemic Stroke
Interventions
OsciPulse system, Flowtron ACS900
Device
Lead sponsor
OsciFlex LLC
Industry
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting Not applicable Interventional

Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

NCT06943586
View directory record Official record
Conditions
Stroke, Transient Ischemic Attack (TIA)
Interventions
CYP2C19 Genotype Guided DAPT (dual antiplatelet therapy)
Genetic
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Completed No phase listed Observational

Assessment of Markers of Stress in Acute Ischemic Stroke With Hyperglycemia

NCT03318679
View directory record Official record
Conditions
Ischemic Stroke, Hyperglycemia
Interventions
No intervention is planned.
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 100 Years
Enrollment
88 participants
Timeline
2017 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting Not applicable Interventional

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

NCT07115940
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Endovascular Thrombectomy, Medical Management
Device · Other
Lead sponsor
Amrou Sarraj
Other
Eligibility
18 Years to 85 Years
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Chicago, Illinois • Kansas City, Kansas • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Phase 1 Interventional

Safety Study of Interferon Beta 1a to for Acute Stroke

NCT00097318
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Interferon beta-1a
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 4:22 AM EDT
Active, not recruiting No phase listed Observational

Transitions of Care for Stroke Patients

NCT06011720
View directory record Official record
Conditions
Stroke, Ischemic Stroke, Intracerebral Hemorrhage
Interventions
Improved transition of care.
Other
Lead sponsor
Deviyani Mehta, MD
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting Not applicable Interventional

The Pivotal Study of RapidPulseTM Aspiration System

NCT06029491
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
RapidPulseTM Aspiration System
Device
Lead sponsor
RapidPulse, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
18
States / cities
Torrance, California • New Haven, Connecticut • Jacksonville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Enrolling by invitation Not applicable Interventional

Feasibility of a First-Line Physical Activity Intervention After Stroke

NCT06679803
View directory record Official record
Conditions
Stroke, Ischemic Stroke, Hemorrhagic Stroke
Interventions
Physical Activity Chats after Stroke (PA-ChatS)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting Not applicable Interventional

RIsE Stroke Mobility Study

NCT07638462
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
activPAL device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 4:22 AM EDT
Recruiting Not applicable Interventional

SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

NCT03737786
View directory record Official record
Conditions
Acute Stroke
Interventions
Tight control of end-tidal CO2 levels
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 110 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Jul 21, 2026, 4:22 AM EDT
Active, not recruiting Not applicable Interventional

Visual Rehabilitation After Occipital Stroke

NCT04798924
View directory record Official record
Conditions
Stroke, Ischemic, Quadrantanopia, Vision Loss Partial, Visual Field Defect, Peripheral, Peripheral Visual Field Defect of Both Eyes, Peripheral Visual Field Defect, Hemianopsia, Hemianopia, Homonymous Hemianopia, Homonymous Hemianopsia, Visual Fields Hemianopsia, Occipital Lobe Infarct, Quadrantanopsia, Stroke Hemorrhagic
Interventions
Subacute Training in the intact field, Subacute Training in the blind field, Chronic Training in the blind field
Device
Lead sponsor
University of Rochester
Other
Eligibility
21 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Jul 21, 2026, 4:22 AM EDT
Completed Phase 4 Interventional

Antiplatelet Therapy to Prevent Stroke in African Americans

NCT00004727
View directory record Official record
Conditions
Stroke, Cerebral Infarction
Interventions
aspirin, ticlopidine
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
29 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 21, 2026, 4:22 AM EDT
Completed No phase listed Observational

Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease

NCT02121028
View directory record Official record
Conditions
Intracranial Vascular Disorders
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 99 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
10
States / cities
Birmingham, Alabama • Los Angeles, California • Gainesville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Jul 21, 2026, 4:22 AM EDT