- Conditions
- Knee Osteoarthritis
- Interventions
- Hyaluronan, Autologous conditioned plasma
- Drug · Biological
- Lead sponsor
- Andrews Research & Education Foundation
- Other
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida
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Showing 25–48
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- Conditions
- Osteoarthritis, Joint Diseases
- Interventions
- Traditional exercise therapy for knee osteoarthritis, Knee stability training
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Opioid
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 36
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Cerritos, California + 33 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Strength training, Aerobic conditioning, Delayed exercise
- Behavioral
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2011
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteo Arthritis Knee, Total Knee Replacement
- Interventions
- Total Knee Arthroplasty using LEGION™ Total Knee System
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2020
- U.S. locations
- 5
- States / cities
- Vero Beach, Florida • Des Moines, Iowa • Louisville, Kentucky + 2 more
- Conditions
- Osteoarthritis
- Interventions
- Tranexamic Acid (TXA), ε-Aminocaproic Acid (EACA)
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa
- Conditions
- Arthritis, Degenerative
- Interventions
- Experimental: 3VM1001 active 2g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 4 times daily, Placebo: 3VM1001 vehicle 2g Cream 3 times daily, Placebo: 3VM1001 vehicle 3g Cream 3 times daily, Placebo: 3VM1001 vehicle 3g Cream 4 times daily
- Drug
- Lead sponsor
- CDA Research Group, Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 4
- States / cities
- La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more
- Conditions
- Osteoarthritis
- Interventions
- Omnibond Topical Skin Adhesive, Dermabond Advanced Topical Skin Adhesive
- Device
- Lead sponsor
- Center for Innovation and Research Organization
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 310 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- New York, New York • New Albany, Ohio • Philadelphia, Pennsylvania + 1 more
- Conditions
- Osteo Arthritis Knee
- Interventions
- Melatonin 5 mg, Placebo
- Drug · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee
- Interventions
- Liposomal bupivacaine, Standard of Care
- Drug
- Lead sponsor
- OhioHealth
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Osteo Arthritis Knee
- Interventions
- Geniculate Artery Embolization, Sham Procedure
- Device · Diagnostic Test
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Woodbridge, Virginia
- Conditions
- Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
- Interventions
- ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Knee Osteoarthritis
- Interventions
- Resistance Exercise, KAATSU exercise
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Osteoarthritis, Articular Cartilage, Musculoskeletal Disorders
- Interventions
- Platelet-Rich Plasma (PRP) Injections, Centrifuge, Control saline injection
- Drug · Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty, Total Knee Replacement
- Interventions
- Persona IQ
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- At-Home Monitoring
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Osteoarthritis
- Interventions
- Self-Administered Acupressure
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Knee Osteoarthritis
- Interventions
- Whole Body Vibration
- Other
- Lead sponsor
- California State University, Fullerton
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fullerton, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Infliximab, Placebo, Standard of Care: Methylprednisolone acetate
- Drug
- Lead sponsor
- Herbert Lindsley, MD
- Other
- Eligibility
- 35 Years to 85 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Custom Patient Instrumentation, Conventional Instruments
- Other
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 3
- States / cities
- Mooresville, Indiana • Bartlesville, Oklahoma • Reston, Virginia
- Conditions
- Osteoarthritis, Knee
- Interventions
- Stepped Exercise Program, Arthritis Education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 345 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Osteoarthritis
- Interventions
- RTX-GRT7039
- Drug
- Lead sponsor
- Grünenthal GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 714 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 27
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Anaheim, California + 24 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Joint line ultrasound, Joint line landmark, Suprapatellar ultrasound guided, Suprapatellar Landmark
- Procedure
- Lead sponsor
- Andrews Research & Education Foundation
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2018
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida