- Conditions
- Arthropathy of Knee Joint, Arthropathy of Hip Joint
- Interventions
- personalized prehabilitation
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2029
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
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Showing 25–48
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- Conditions
- Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Interventions
- Arm 1-Kronos brace, Arm 2-Breg T-Scope brace
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Obesity, Osteoarthritis
- Interventions
- gastric bypass surgery
- Procedure
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 35 Years to 60 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Arthropathy of Knee
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 363 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2014
- U.S. locations
- 4
- States / cities
- Durham, North Carolina • New Albany, Ohio • Temple, Texas + 1 more
- Conditions
- Total Knee Replacement, Wound Complication
- Interventions
- Skin closure using skin adhesive, Skin closure without skin adhesive
- Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 216 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Replacement
- Interventions
- Interview
- Other
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- Not listed
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological, Breathing Techniques, Breathing Exercises, Hypothalamic Pituitary Adrenal, Relaxation, Relaxation Therapy, Cortisol, Postoperative Pain, Postoperative Anxiety, Postoperative Depression, Quality of Recovery (QoR-15)
- Interventions
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Behavioral
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Knee Arthroscopy
- Interventions
- Chloroprocaine, Mepivacaine, General Anesthetics
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Septic Arthritis
- Interventions
- Arthroscopic Irrigation and Debridement, Open Arthrotomy with irrigation and debridement
- Procedure
- Lead sponsor
- Texas Tech University Health Sciences Center, El Paso
- Other
- Eligibility
- Not listed
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Degenerative Lesion of Articular Cartilage of Knee
- Interventions
- ADSC Application, Microfracture
- Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 3
- States / cities
- Redwood City, California • Santa Monica, California • Denver, Colorado
- Conditions
- Surgical Site Infection
- Interventions
- One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
- Procedure
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 343 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 5
- States / cities
- Chicago, Illinois • New York, New York • Charlotte, North Carolina + 2 more
- Conditions
- Degenerative Arthritis of Knee
- Interventions
- VISIONAIRE Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Other
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 134 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 6
- States / cities
- Park Ridge, Illinois • Springfield, Illinois • St Louis, Missouri + 3 more
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture, Patella Fracture, Tibial Shaft Fracture with or Without Associated Fibula Fracture, Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Tibial Pilon Fracture, Talar Head, Neck, Body, or Process Fractures, Calcaneus Fractures, Lisfranc Injuries, Isolated or Multiple Metatarsal Fractures, Phalanx Fractures of the Foot, Single or Multiple, Clavicle Fractures, Proximal Humerus Fractures, Humeral Shaft Fractures, Distal Humerus Fractures (intra or Extra-articular), Olecranon Fractures, Radial Head or Neck Fractures, Elbow Fractures Involving a Combination of Fractures of the Radius and Uln, Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft), Distal Radius Fractures
- Interventions
- Opioid-free pain treatment
- Other
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Custom Patient Instrumentation, Conventional Instruments
- Other
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 3
- States / cities
- Mooresville, Indiana • Bartlesville, Oklahoma • Reston, Virginia
- Conditions
- Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
- Interventions
- Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
- Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Arthroplasty, Knee Replacement, Wound Healing
- Interventions
- Zip Surgical Skin Closure, Steel Staples
- Device
- Lead sponsor
- ZipLine Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Post-surgical Pain
- Interventions
- AYX1 Injection 660 mg/6 mL, Placebo Injection 6 mL
- Drug
- Lead sponsor
- Adynxx, Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 6 more
- Conditions
- Postsurgical Pain
- Interventions
- Placebo Injection, AYX1 Injection 110 mg, AYX1 Injection 330 mg
- Drug
- Lead sponsor
- Adynxx, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 7
- States / cities
- Sheffield, Alabama • Phoenix, Arizona • Boynton Beach, Florida + 4 more
- Conditions
- Osteoarthritis
- Interventions
- Modafinil, Gabapentin, Placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
- Interventions
- ACTIVE cryoneurolysis, SHAM cryoneurolysis
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Chronic Pain
- Interventions
- Spinal cord stimulator (Boston Scientific)
- Device
- Lead sponsor
- Coastal Orthopedics & Sports Medicine
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Bradenton, Florida
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- CORI™ KNEE TENSIONER
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- New York, New York • New Albany, Ohio • Pittsburgh, Pennsylvania + 1 more
- Conditions
- Osteoarthritis, Degenerative Joint Disease
- Interventions
- Motivational Interviewing (MI), Financial Incentives
- Behavioral · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts