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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:45 PM EDT

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Showing 769–792 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Recruiting No phase listed Observational

Clinical Evaluation of WaveLight Plus LASIK

NCT07127757
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavelight Plus LASIK
Device
Lead sponsor
Laser Defined Vision
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 23, 2026, 6:45 PM EDT
Recruiting Phase 1 Interventional

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

NCT07145112
View directory record Official record
Conditions
Glioblastoma
Interventions
Laser interstitial thermal therapy, Lomustine
Procedure · Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 6:45 PM EDT
Not listed Not applicable Interventional

The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability

NCT01554267
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Mastectomy
Interventions
Laser-Assisted ICG Dye Angiography (SPY System)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Oct 23, 2026, 6:45 PM EDT
Withdrawn Not applicable Interventional

Laser Treated Scars and Optical Coherence Tomography (OCT)

NCT05166395
View directory record Official record
Conditions
Scar
Interventions
Er:YAG laser
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 23, 2026, 6:45 PM EDT
Completed No phase listed Observational

Laser Spectroscopy of Breast Tissue Through a Needle Device

NCT00918788
View directory record Official record
Conditions
Breast Cancer
Interventions
biologic sample preservation procedure, immunohistochemistry staining method, light microscopy, medical chart review, histopathologic examination, needle biopsy, spectroscopy
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional Results available

CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia

NCT01032044
View directory record Official record
Conditions
Barrett Syndrome, Barrett's Syndrome, Barrett's Esophagus, Barrett Esophagus, Adenocarcinoma
Interventions
Standard endoscopic evaluation, pCLE guided evaluation
Device
Lead sponsor
Mauna Kea Technologies
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
Jacksonville, Florida • Chicago, Illinois • Kansas City, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 23, 2026, 6:45 PM EDT
Active, not recruiting Phase 4 Interventional

Effect of Rhopressa on Intraocular Pressure (IOP) in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension Post-SLT

NCT06865144
View directory record Official record
Conditions
Primary Open Angle Glaucoma or Ocular Hypertension
Interventions
Netarsudil ophthalmic solution 0.02%, Artificial tears
Drug
Lead sponsor
East Coast Institute for Research
Network
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional Results available

A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism

NCT04111757
View directory record Official record
Conditions
Myopia, Myopic Astigmatism
Interventions
Technolas® TENEO 317 Model 2
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
10
States / cities
Newport Beach, California • Blaine, Minnesota • Bloomington, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Phase 4 Interventional Results available

RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients

NCT05386368
View directory record Official record
Conditions
Carbon Dioxide Laser, Photoaging
Interventions
ReCell
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 23, 2026, 6:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Blood Flow and Pain Crises in People With Sickle Cell Disease

NCT01568710
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional

Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery

NCT02561104
View directory record Official record
Conditions
Incipient Cataract, Senile Nuclear Sclerosis
Interventions
Laser-assisted cataract surgery., Traditional manual phacoemulsification
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 99 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional

MacTel Laser Study

NCT03321916
View directory record Official record
Conditions
Macular Telangiectasia
Interventions
577-nm PASCAL laser
Device
Lead sponsor
The Lowy Medical Research Institute Limited
Other
Eligibility
21 Years to 79 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Not applicable Interventional Results available

Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells

NCT00478036
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
Acular LS, Pred Forte, Refresh Tears
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Over-The-Counter Use of Low Level Laser Light Therapy for Body Contouring of the Waist, Hips and Thighs

NCT02167867
View directory record Official record
Conditions
Circumference Reduction
Interventions
Lay End Users, Treatment Subject Group
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 23, 2026, 6:45 PM EDT
Not yet recruiting Not applicable Interventional

Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic Hyperplasia

NCT07772232
View directory record Official record
Conditions
Benign Prostate Hypertrophy(BPH), Lower Urinary Track Symptoms
Interventions
Device - HoLEP with MOSES 2.0, RWJA with Hydros Robotic System
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 23, 2026, 6:45 PM EDT
Recruiting Phase 2 Interventional

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

NCT06228066
View directory record Official record
Conditions
Small Cell Carcinoma of the Bladder, High Grade Neuroendocrine Tumors of the Urinary Tract
Interventions
Lurbinectedin, Avelumab
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 23, 2026, 6:45 PM EDT
Completed No phase listed Observational

Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome

NCT01622049
View directory record Official record
Conditions
Twin Twin Transfusion Syndrome
Interventions
Selective Laser Photocoagulation of Communicating Vessels
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Not applicable Interventional Results available

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

NCT02881047
View directory record Official record
Conditions
Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions
CO2 Laser, Ultrasound, Skin Biopsy
Device · Radiation · Diagnostic Test
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Not applicable Interventional

Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty

NCT02327312
View directory record Official record
Conditions
Primary Open-Angle Glaucoma
Interventions
Stents, Laser, Laser Trabeculoplasty
Device · Procedure
Lead sponsor
Glaukos Corporation
Industry
Eligibility
35 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
9
States / cities
Glendale, Arizona • Fayetteville, Arkansas • Hemet, California + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 23, 2026, 6:45 PM EDT
Recruiting Not applicable Interventional

Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker Skin Color

NCT06406621
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Laser hair depilation, Standard of Care (SOC)
Procedure · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
10 Years to 21 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Phase 1 Interventional

LITT and Pembrolizumab in Recurrent Brain Metastasis

NCT04187872
View directory record Official record
Conditions
Melanoma, Non-small Cell Lung Carcinoma (NSCLC), Renal Cell Carcinoma (RCC), Small-cell Lung Cancer, Head and Neck Squamous Cell Cancer, Classical Hodgkin Lymphoma, Primary Mediastinal Large B-Cell Lymphoma, Urothelial Carcinoma, Microsatellite Instability-High Cancer, Gastric Cancer, Esophageal Cancer, Cervical Cancer, Hepatocellular Carcinoma, Merkel Cell Carcinoma, Brain Metastases, Adult
Interventions
LITT + Pembrolizumab
Combination Product
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Oct 23, 2026, 6:45 PM EDT
Terminated Not applicable Interventional

Study to Evaluate the Safety and Performance of Spectranetics Laser w/Adjunct PTA and Gore Viabahn Endoprosthesis for Treatment of SFA Instent Restenosis

NCT00712257
View directory record Official record
Conditions
Restenosis
Interventions
Spectranetics Laser with adjunct PTA and Gore VIABAHN Endoprosthesis with Heparin Bioactive Surface
Device
Lead sponsor
VIVA Physicians
Other
Eligibility
18 Years to 89 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser

NCT02430428
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Carl Zeiss Meditec VisuMax Femtosecond Laser
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Greenwood Village, Colorado • Leawood, Kansas • Sioux Falls, South Dakota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Oct 23, 2026, 6:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin

NCT03380845
View directory record Official record
Conditions
Acne Scars
Interventions
Fraxel Restore, Fractora
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 23, 2026, 6:45 PM EDT