- Conditions
- Mitral Valve Failure
- Interventions
- Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
- Device
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- NIH
- Eligibility
- 21 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 6
- States / cities
- Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 262
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Heart Failure
- Interventions
- Pacing Lead
- Device
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 441 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 20
- States / cities
- Long Beach, California • Palo Alto, California • Newark, Delaware + 17 more
- Conditions
- Congestive Heart Failure
- Interventions
- Corox OTW Steroid Left Ventricular Lead
- Device
- Lead sponsor
- Biotronik, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 221 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Lake Oswego, Oregon
- Conditions
- Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
- Interventions
- Finerenone (Kerendia, BAY94-8862)
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- Up to 18 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 22
- States / cities
- Aurora, Colorado • Wilmington, Delaware • Gainesville, Florida + 18 more
- Conditions
- Heart Failure
- Interventions
- Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Heart Failure
- Interventions
- Glial growth factor 2/ Neuregulin 1β3, Placebo
- Drug · Other
- Lead sponsor
- Acorda Therapeutics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • Nashville, Tennessee
- Conditions
- Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
- Interventions
- Pulmonary Artery Denervation (PADN), Sham procedure control
- Device
- Lead sponsor
- Pulnovo Medical, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 750 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 6
- States / cities
- Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
- Conditions
- Heart Failure
- Interventions
- Apixaban, Warfarin, LVAD implant
- Drug · Device
- Lead sponsor
- Palak Shah
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Falls Church, Virginia
- Conditions
- Current or Recent History of Atrial Fibrillation
- Interventions
- bucindolol hydrochloride, metoprolol succinate, Placebo oral capsule
- Drug · Other
- Lead sponsor
- ARCA Biopharma, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 267 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 48
- States / cities
- Anchorage, Alaska • Phoenix, Arizona • East Palo Alto, California + 43 more
- Conditions
- Heart Failure, Left Ventricle Remodeling
- Interventions
- Revivent TC System
- Device
- Lead sponsor
- BioVentrix
- Industry
- Eligibility
- 18 Years and older
- U.S. locations
- 2
- States / cities
- Cleveland, Ohio • Hershey, Pennsylvania
- Conditions
- Mitral Valve Regurgitation, Congestive Heart Failure, Cardiomyopathy
- Interventions
- 3 dimensional echocardiography
- Procedure
- Lead sponsor
- Juan Crestanello, MD
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Valvular Heart Disease Patients, Aortic Stenosis, Mitral Regurgitation, Left Ventricular Diastolic Dysfunction
- Interventions
- Kosmos Torso-One AI-guided Point-of-Care Ultrasound (EchoNous, Inc.)
- Device
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 65 Years to 85 Years
- Enrollment
- 1,088 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Dallas, Texas
- Conditions
- Congestive Heart Failure
- Interventions
- Medtronic 4195 active fixation LV lead and Medtronic passive fixation LV lead
- Device
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Heart Failure
- Interventions
- Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT
- Device
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 684 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2011
- U.S. locations
- 34
- States / cities
- Huntsville, Alabama • Anchorage, Alaska • Redwood City, California + 31 more
- Conditions
- Heart Failure, Congestive Heart Failure
- Interventions
- Isosorbide Dinitrate, Isosorbide Dinitrate + Hydralazine, Placebo
- Drug
- Lead sponsor
- Corporal Michael J. Crescenz VA Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Aortic Valve Stenosis
- Interventions
- SAPIEN 3 THV, Optimal Heart Failure Therapy
- Device · Biological
- Lead sponsor
- Cardiovascular Research Foundation, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 178 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2025
- U.S. locations
- 46
- States / cities
- Chandler, Arizona • La Jolla, California • Los Angeles, California + 37 more
- Conditions
- Heart Failure
- Interventions
- Cardiac pacing
- Device
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 4
- States / cities
- Davenport, Iowa • Yardley, Pennsylvania • Richmond, Virginia + 1 more
- Conditions
- Heart Failure, Systolic, Left Bundle Branch Block
- Interventions
- Cardiac Resynchronization Therapy (CRT) implantation
- Procedure
- Lead sponsor
- Emory University
- Other
- Eligibility
- Not listed
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Stage D Heart Failure
- Interventions
- Sacubitril-Valsartan, Usual care (standard-of-care) arm
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Congestive Heart Failure
- Interventions
- carvedilol controlled release, carvedilol immediate release
- Drug
- Lead sponsor
- CTI-1, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 318 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 75
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 67 more
- Conditions
- Heart Failure, Chronic Systolic Heart Failure, Renal Failure, Cardiorenal Syndrome
- Interventions
- Selective Cytopheretic Device
- Device
- Lead sponsor
- Lenar Yessayan
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Advanced Heart Failure, Mechanical Circulatory Support, Left Ventricular Assist Device, Palliative Care
- Interventions
- Palliative care intervention
- Behavioral
- Lead sponsor
- Medstar Health Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Fairfax, Virginia
- Conditions
- Heart Failure, Gastrointestinal Bleeding
- Interventions
- Omega 3 fatty acids, Placebo
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Coagulation
- Interventions
- TTP889, Placebo
- Drug
- Lead sponsor
- vTv Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2009
- U.S. locations
- 3
- States / cities
- New York, New York • Spokane, Washington