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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.

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Filters: Condition: MND (Motor Neurone DIsease) Clear all

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 766 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2020
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Motor Neuron Disease
Interventions: FLX-787-ODT (orally disintegrating tablet), Placebo ODT; Drug
Lead sponsor: Flex Pharma, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 35
States / cities: Scottsdale, Arizona • Sacramento, California • San Francisco, California + 29 more

Conditions: Amyotrophic Lateral Sclerosis (ALS), Familial Amyotrophic Lateral Sclerosis, ALS With Frontotemporal Dementia (ALS/FTD), Lou Gehrig's Disease, Motor Neuron Disease (MND), Primary Lateral Sclerosis (PLS), Sporadic ALS (SALS)
Interventions: Genetic study of ALS families; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 13,521 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1991 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Muscle Cramps in Amyotrophic Lateral Sclerosis
Interventions: Mexiletine, Placebo; Drug
Lead sponsor: Bjorn Oskarsson, MD; Other
Eligibility: 21 Years to 89 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 6
States / cities: Chester, California • La Jolla, California • Los Angeles, California + 3 more

Conditions: Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS), Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions: Transcutaneous Electrical Nerve Stimulation to reduce facial pain and improve jaw range of motion in ALS and PLS; Device
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Davie, Florida

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Masitinib (6.0), Riluzole, Placebo, Masitinib (4.5); Drug
Lead sponsor: AB Science; Industry
Eligibility: 18 Years to 81 Years
Enrollment: 495 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 6
States / cities: Birmingham, Alabama • Los Angeles, California • Lexington, Kentucky + 3 more

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: VHB937, Placebo; Biological · Other
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 21
States / cities: La Jolla, California • Loma Linda, California • Los Angeles, California + 18 more

Conditions: Amyotrophic Lateral Sclerosis (ALS), Motor Neuron Disease (MND), Primary Lateral Sclerosis (PLS)
Interventions: Education about treatment options, Dietary Supplements: Vitamins, Minerals, Herbs, etc., Meditation, Prayer, Talk Therapy, Affirmations, Journaling, etc., Diet, various diets will be observed, Exercise, physical therapy, occupational therapy, speech therapy, sauna, EMS, massage and other therapies, ALS medications and other medications, Physical and emotional support; Other · Dietary Supplement · Behavioral + 1 more
Lead sponsor: Healing Advocates Registry and Ministry; Other
Eligibility: 18 Years to 110 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2036
U.S. locations: 1
States / cities: Park City, Utah

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Oxepa, Jevity 1.5, Jevity 1.0; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 13
States / cities: Phoenix, Arizona • Irvine, California • San Francisco, California + 10 more

Conditions: ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease, PMA - Progressive Muscular Atrophy, PBP - Progressive Bulbar Palsy
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 90 Years
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2030
U.S. locations: 14
States / cities: Loma Linda, California • Los Angeles, California • Gainesville, Florida + 10 more

Conditions: Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised, Amyotrophic Lateral Sclerosis Assessment Questionnaire-40; Other
Lead sponsor: TidalHealth, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Salisbury, Maryland

Conditions: Cystic Fibrosis, Motor Neuron Disease, Airway Clearance Impairment
Interventions: MN 4000; Device
Lead sponsor: Hill-Rom; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, PLS, Motor Neuron Disease, Lou Gehrigs Disease, Familial Disease, Amyotrophic Lateral Sclerosis, Sporadic, Muscular Dystrophy, Miyoshi Myopathy, Amyotrophic Lateral Sclerosis With Dementia
Interventions: Not listed
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2024
U.S. locations: 1
States / cities: Worcester, Massachusetts

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Establishment of a Tissue Bank (Blood, CSF) for the Understanding of Motor Neuron Disease (MND)

A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.

Genetics of Familial and Sporadic ALS

Mexiletine for the Treatment of Muscle Cramps in ALS

Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

Healing ALS Registry Observational Study (HAROS)

High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis

ALS/MND Natural History Study Data Repository

Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth

MN4000 for Treatment of CF and MND Patients in the Home Setting

Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders