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ClinicalTrials.gov public records Last synced Oct 14, 2026, 7:45 PM EDT

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Showing 817–840 of 6,280 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism and Nutrition Disorders Clear all
Active, not recruiting Phase 3 Interventional

A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)

NCT07400653
View directory record Official record
Conditions
Obesity, Overweight and/or Obesity, Overweight, Diabetes, Type 2, Type 2 Diabetes
Interventions
PF-08653944, Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
1,078 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
55
States / cities
Anaheim, California • Canoga Park, California • Cerritos, California + 45 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

NCT07654972
View directory record Official record
Conditions
Obesity, Overweight
Interventions
LY4174794, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Antonio, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Completed No phase listed Observational

A Comparison of Two Caloric Supplements in the Prevention of Weight Loss in Patients With AIDS Who Take Daily Multivitamin and Mineral Supplements

NCT00001077
View directory record Official record
Conditions
HIV Infections, HIV Wasting Syndrome
Interventions
Multivitamin and mineral supplements, Peptamen, NuBasics
Dietary Supplement
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
536 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1998
U.S. locations
17
States / cities
San Francisco, California • Denver, Colorado • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2013 · Synced Oct 14, 2026, 7:45 PM EDT
Active, not recruiting Phase 3 Interventional

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

NCT07284875
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Ribupatide, Placebo
Drug
Lead sponsor
Kailera
Industry
Eligibility
18 Years and older
Enrollment
2,530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
24
States / cities
Anniston, Alabama • Birmingham, Alabama • Cullman, Alabama + 21 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Phase 2 Interventional

Weight Management in Nonalcoholic Steatohepatitis

NCT00266019
View directory record Official record
Conditions
Fatty Liver
Interventions
Weight Management (diet, exercise, and behavior modification)
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Oct 14, 2026, 7:45 PM EDT
Active, not recruiting Phase 3 Interventional

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

NCT06993792
View directory record Official record
Conditions
Obesity, Overweight, Type 2 Diabetes
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
35
States / cities
Sun City West, Arizona • Tucson, Arizona • San Ramon, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Brain Dopamine Function in Human Obesity

NCT03648892
View directory record Official record
Conditions
Obesity, Healthy Volunteers, Overweight
Interventions
[c11] raclopride, [18F]fallypride
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 14, 2026, 7:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Relation of Consummatory & Anticipatory Food Reward to Obesity

NCT02084836
View directory record Official record
Conditions
Obesity
Interventions
Functional Magnetic Resonance Imaging
Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
14 Years to 17 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 14, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Folic Acid Salt Study (FISFA Zambia)

NCT06734611
View directory record Official record
Conditions
Folate Deficiency, Neural Tube Defects
Interventions
Fortified Iodized Salt with Folic Acid (FISFA)
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Vitamin D Supplementation and Immune Function

NCT01399151
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D - Treatment 1, Vitamin D - Treatment 2, Vitamin D - Treatment 3
Dietary Supplement
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 49 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2014 · Synced Oct 14, 2026, 7:45 PM EDT
Terminated Not applicable Interventional

RCT of Caloric Restriction vs. Alternate-Day Fasting in Non-Alcoholic Fatty Liver Disease

NCT03365531
View directory record Official record
Conditions
NAFLD, Obesity, Diabetes Mellitus, Type 2
Interventions
Alternate Daily Fasting (ADF), Caloric Restriction (CR)
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

NCT04257929
View directory record Official record
Conditions
Prader-Willi Syndrome
Interventions
Pitolisant oral tablets, Placebo oral tablet
Drug
Lead sponsor
Harmony Biosciences Management, Inc.
Industry
Eligibility
6 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
13
States / cities
San Diego, California • San Ramon, California • Santa Monica, California + 10 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional

Changes in Body Composition Including Muscle With Anti-Obesity Medications, Both With and Without Exercise

NCT07698145
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Standard Medical Care with an Obesity Management Medication, Cardiovascular Exercise Training, Resistance Exercise Training, Nutrition Counseling
Other · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Promoting Resilience to Food Commercials Decreases Susceptibility to Unhealthy Food Decision-Making

NCT04905498
View directory record Official record
Conditions
Obesity, Adolescent
Interventions
Commercial Advertising Literacy Training, Control
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
8 Years to 12 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 14, 2026, 7:45 PM EDT
Not listed Not applicable Interventional

Metabolic Optimization Through Diet/Lifestyle Improvements For Youth

NCT04270084
View directory record Official record
Conditions
Dyslipidemias, Obesity
Interventions
Alive-Family
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
10 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Healthy Apple Program in San Francisco

NCT02799433
View directory record Official record
Conditions
Childhood Obesity
Interventions
Usual services + HAP, Usual services
Behavioral
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
2 Years to 5 Years
Enrollment
3,493 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2016 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Effects of Motivating People With Schizophrenia to Exercise

NCT00559572
View directory record Official record
Conditions
Schizophrenia
Interventions
Motivational group sessions, Time and attention control group sessions
Behavioral · Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
22 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Molecular Mechanisms of Exercise Benefits to Insulin Resistant People

NCT04158375
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Resistance Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Reinforcing Value of Added Sugars

NCT02744001
View directory record Official record
Conditions
Obesity
Interventions
Low Added Sugar Diet
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 14, 2026, 7:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Food Environment, Food Insecurity, and Health Behaviors in NH Hispanics

NCT05424367
View directory record Official record
Conditions
Obesity, Food Insecurity
Interventions
Not listed
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Parent-Child Interactions to Enhance Child Health

NCT03982511
View directory record Official record
Conditions
Child Obesity
Interventions
PCIT-Health
Behavioral
Lead sponsor
Central Michigan University
Other
Eligibility
30 Months to 84 Months
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Mount Pleasant, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Auricular Acupuncture in the Treatment of Obesity

NCT02269371
View directory record Official record
Conditions
Obesity
Interventions
Auricular Acupuncture, Sham Acupuncture
Other
Lead sponsor
Mike O'Callaghan Military Hospital
Federal
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 14, 2026, 7:45 PM EDT
Completed Phase 3 Interventional

A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)

NCT06584916
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
27
States / cities
Birmingham, Alabama • Pelham, Alabama • Santa Ana, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 14, 2026, 7:45 PM EDT
Withdrawn No phase listed Observational

Bariatric Surgery Outcomes

NCT01057784
View directory record Official record
Conditions
Morbid Obesity
Interventions
Bariatric surgery.
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 14, 2026, 7:45 PM EDT