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ClinicalTrials.gov public records Last synced Oct 15, 2026, 1:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 567 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obesity Type 2 Diabetes Mellitus Clear all
Withdrawn Not applicable Interventional

The vBlocT2D Study

NCT03355092
View directory record Official record
Conditions
Type2 Diabetes, Obesity
Interventions
vBloc Therapy
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Harbor City, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Phase 3 Interventional

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07533175
View directory record Official record
Conditions
Diabetes Mellitus, Overweight, Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
15
States / cities
Birmingham, Alabama • Escondido, California • Lomita, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional

Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes

NCT01295229
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
laparoscopic Roux-en-Y gastric bypass (RYGB) procedure, Lifestyle Intervention
Procedure · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
25 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Active You: Feasibility of a Unique Physical Activity Program to Prevent Diabetes and Heart Disease

NCT04621045
View directory record Official record
Conditions
Cardiovascular Risk Factor, Prediabetes, Overweight and Obesity, Sedentary Behavior
Interventions
The Physical Activity for The Heart (PATH) intervention, Be Active Your Way Booklet
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Beaver Falls, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Phase 3 Interventional Results available

Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity

NCT03552757
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Semaglutide 1.0 mg, Semaglutide 2.4 mg, Placebo I (Semaglutide), Placebo II (Semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
1,210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
50
States / cities
Buena Park, California • Concord, California • Fresno, California + 42 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Almased Multi-Center Diabetes Intervention Trial

NCT01702012
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Almased Meal Replacement Powder, Group-Based Lifestyle Intervention
Dietary Supplement · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents

NCT06943001
View directory record Official record
Conditions
Obesity and Type 2 Diabetes
Interventions
Fit24+
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
14 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional

The RESET System Pivotal Clinical Trial (Protocol Revision K)

NCT04101669
View directory record Official record
Conditions
Diabetes type2, Obesity
Interventions
RESET Liner, Sham
Device · Other
Lead sponsor
Morphic Medical Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
27
States / cities
Gilbert, Arizona • Tucson, Arizona • Washington D.C., District of Columbia + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional

The Healthy Eating and Active Living to Reverse Diabetes Pilot Study

NCT07316569
View directory record Official record
Conditions
Diabete Type 2, Diabetes, Overweight , Obesity
Interventions
Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Active, not recruiting Phase 2 Interventional

Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM

NCT06005012
View directory record Official record
Conditions
Fibrosis, Liver, Type 2 Diabetes Mellitus in Obese, Non-Alcoholic Fatty Liver Disease
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 79 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online WIC Nutrition Education to Promote Farmers' Market Fruit and Vegetable Purchases and Consumption

NCT02565706
View directory record Official record
Conditions
Cardiovascular Diseases, Cancer, Type 2 Diabetes, Obesity
Interventions
WIC Fresh Start Program, Existing Online Health Education
Behavioral
Lead sponsor
William Paterson University of New Jersey
Other
Eligibility
Female only
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extracellular Vesicles, Insulin Action, and Exercise

NCT06546085
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Exercise
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
30 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Early Phase 1 Interventional

Connecting Smartphones With Electronic Health Record to Facilitate Behavioral Goal Monitoring in Diabetes Care

NCT02664233
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Mobile and connected health
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 15, 2026, 1:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fitness and Sleep in People With Family History of Type 2 Diabetes.

NCT00721084
View directory record Official record
Conditions
Sleep, Physical Fitness, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

NCT05165706
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Obesity, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver, Diet Modification
Interventions
Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate Diet, Dietary Intervention Standard Low Fat Diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
35 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Phase 2 Interventional

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

NCT06717698
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
NNC0519-0130, Placebo, Semaglutide
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
18
States / cities
San Dimas, California • San Ramon, California • Aurora, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed No phase listed Observational

Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk Factors

NCT02896140
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Type 2 diabetes in WhyWAIT Program
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Phase 4 Interventional Results available

Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes

NCT02014740
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Liraglutide, Metformin
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 15, 2026, 1:33 AM EDT
Completed No phase listed Observational

Methods for Measuring Insulin Sensitivity

NCT00001625
View directory record Official record
Conditions
Obesity, Hypertension, Diabetes-Mellitus, Non-Insulin Dependent
Interventions
Not listed
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 65 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist

NCT06851858
View directory record Official record
Conditions
Endocrinology, Diabetes, Type II, Obesity
Interventions
AZD6234, Placebo to match
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 75 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
18
States / cities
Birmingham, Alabama • Mobile, Alabama • Doral, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional

Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians

NCT00608387
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension, Obesity, Tobacco Use Cessation
Interventions
Chronic disease management Web-based software
Behavioral
Lead sponsor
Black Hills Center for American Indian Health
Other
Eligibility
18 Years to 75 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 15, 2026, 1:33 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

NCT05838287
View directory record Official record
Conditions
Type 2 Diabetes Mellitus in Obese, Heart Failure With Preserved Ejection Fraction
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
30 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth

NCT00693511
View directory record Official record
Conditions
Obesity and Type 2 Diabetes
Interventions
Circuit Training, Circuit training + motivational interviewing
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
14 Years to 18 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Oct 15, 2026, 1:33 AM EDT
Completed Phase 2 Interventional Results available

Study of VI-0521 Compared to Placebo in the Glycemic Management of Obese Diabetics

NCT00486291
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
VI-0521, Placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
9
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Oct 15, 2026, 1:33 AM EDT