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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obesity and Cardiovascular Risk Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

NCT00139477
View directory record Official record
Conditions
Obesity
Interventions
Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
Drug · Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
7 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 23, 2026, 8:24 PM EDT
Completed No phase listed Observational

Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk Factors

NCT02896140
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Type 2 diabetes in WhyWAIT Program
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Jul 23, 2026, 8:24 PM EDT
Completed No phase listed Observational

Cardiometabolic Risk, Obesity and Cardiovascular Disease in People With Spinal Cord Injury

NCT01204632
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Phase 3 Interventional Results available

Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects

NCT01764386
View directory record Official record
Conditions
Obesity, Overweight
Interventions
NB, CLI, Usual Care
Drug · Behavioral
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 60 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
15
States / cities
Denver, Colorado • St Louis, Missouri • Cary, North Carolina + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2015 · Synced Jul 23, 2026, 8:24 PM EDT
Completed No phase listed Observational

Association of Mood With Risk for Atherosclerosis

NCT04298944
View directory record Official record
Conditions
Mood Disorders, Hypertension, Overweight and Obesity, Vascular Stiffness, Sleep, Elevated Blood Pressure
Interventions
Cardiovascular Assessments, Actigraphy, Laboratory assessments, Emotional/ Behavioural assessments
Diagnostic Test · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 22 Years
Enrollment
37 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional

CardioMetabolic Program Meets eHealth: Redesign and Evaluation for Optimal Reach and Impact

NCT02246400
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Pre-diabetes, Type 2 Diabetes, Cardiovascular Disease
Interventions
eCMP
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Jul 23, 2026, 8:24 PM EDT
Recruiting Not applicable Interventional

Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure

NCT06364644
View directory record Official record
Conditions
Type2diabetes, Heart Failure, Obesity
Interventions
Community Champions, Homegrown Heroes
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 70 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Hagerstown, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 23, 2026, 8:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome

NCT02205021
View directory record Official record
Conditions
Obesity
Interventions
No intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 91 Years
Enrollment
303 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart-Healthy Lenoir Lifestyle Study

NCT01433484
View directory record Official record
Conditions
Cardiovascular Disease, Obesity
Interventions
Maintenance of Weight Loss--Control, Maintenance of Weight Loss--Experimental
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
339 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Kinston, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2017 · Synced Jul 23, 2026, 8:24 PM EDT
Recruiting Not applicable Interventional

A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

NCT07238556
View directory record Official record
Conditions
Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity, Cardiovascular Disease
Interventions
Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
3
States / cities
Farmington, Connecticut • Hartford, Connecticut • Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Phase 1 Interventional

Effect of High Monounsaturated Fat Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes

NCT00622960
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes
Interventions
High-MUFA diet, High-CHO diet
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
30 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2008 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Liraglutide 3.0 on Body Fat Distribution

NCT03038620
View directory record Official record
Conditions
Obesity, Visceral, Cardiovascular Diseases, Fat Disorder
Interventions
Liraglutide, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
35 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2021 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

NCT02551640
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Prediabetic State, Hypertension, Prehypertension, Obesity
Interventions
FeatForward App (on study smartphone)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Charlestown, Massachusetts • Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Jul 23, 2026, 8:24 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.

NCT04939220
View directory record Official record
Conditions
Cardiopulmonary Disease
Interventions
TEE with SGA, TEE with Deep Sedation
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Jul 23, 2026, 8:24 PM EDT
Terminated Phase 2 Interventional Results available

The Effects of Rimonabant, on Weight and Metabolic Risk Factors

NCT00547118
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Obesity, Hypertension, Smoking
Interventions
Rimonabant, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
4
States / cities
Baltimore, Maryland • Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Jul 23, 2026, 8:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease

NCT02075710
View directory record Official record
Conditions
Overweight and Obesity
Interventions
High sugar/meal feed, High sugar/nibble, High fat/meal feed, High fat/nibble, High sugar/ 3 meals a day, High fat/ 3 meals a day
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smart Walk: A Physical Activity Program for African American Women

NCT02823379
View directory record Official record
Conditions
Physical Activity
Interventions
Physical Activity, Wellness
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
24 Years to 49 Years · Female only
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional Results available

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

NCT04705779
View directory record Official record
Conditions
Heart Diseases, Stroke, Pre-diabetes, Hypertension, Obesity, Overweight, Stress
Interventions
HARMONY, Nutrition and Exercise Education (NEEW)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Phase 3 Interventional

Effect of Mindful Eating on Body Mass Index in Obese Adolescents

NCT01764113
View directory record Official record
Conditions
Adolescent Obesity
Interventions
Mindful Eating, Standard dietary counselling
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
14 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2014 · Synced Jul 23, 2026, 8:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Infant Egg Consumption on Child Health and Cognition Development

NCT04345185
View directory record Official record
Conditions
Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome, Food Allergy, Cognitive Developmental Delay
Interventions
Infant egg consumption (i.e., age of introduction and frequency of intake)
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
0 Years to 15 Years
Enrollment
5,374 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Jul 23, 2026, 8:24 PM EDT
Terminated Not applicable Interventional

Nutritional Treatment of Overweight Adolescents With Cardiovascular Risk Factors (PowerUp)

NCT00477477
View directory record Official record
Conditions
Childhood Obesity, Dyslipidemia, Insulin Resistance, Hypertension
Interventions
Diet
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Training and Time-restricted Feeding in Overweight and Obese Adults

NCT03823872
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Time restricted feeding, Normal feeding
Other
Lead sponsor
Kyle Hackney
Other
Eligibility
35 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effect of Antioxidants on Skin Blood Flow During Local Heating

NCT03680638
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor, Vasodilation
Interventions
Control (Lactated Ringer's), Tempol, Apocynin, Allopurinol
Other · Drug
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Jul 23, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Grapefruit Feeding Trial in Healthy, Overweight Adults

NCT01452841
View directory record Official record
Conditions
Weight Loss, Obesity, Cardiovascular Risk Factors
Interventions
Grapefruit, Control
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 16, 2011 · Synced Jul 23, 2026, 8:24 PM EDT