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ClinicalTrials.gov public records Last synced Oct 28, 2026, 10:18 AM EDT

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Showing 937–960 of 2,396 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstruction Clear all
Recruiting Not applicable Interventional

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

NCT07191860
View directory record Official record
Conditions
Adult Subjects With Symptomatic Benign Airway Obstruction, Adult Benign Central Airway Stenosis, Adult Tracheobronchial Stenosis, Tracheal Stenosis, Central Airway Stenosis, Central Airway Obstruction
Interventions
The Airiver Pulmonary drug-coated balloon (DCB) dilation, Commercial airway balloon dilation
Combination Product · Device
Lead sponsor
Airiver Medical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 28, 2026, 10:18 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine Alone

NCT03658109
View directory record Official record
Conditions
Gynecologic Cancer
Interventions
Lidocaine Bolus Infusion, QL block, Saline Bolus Infusion, Simulated QL block
Drug · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 69 Years · Female only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement

NCT02805309
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Exercise, Cognitive behavioral interventions, Attention control education program
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Oct 28, 2026, 10:18 AM EDT
Enrolling by invitation Phase 4 Interventional

A Study of Paravertebral Block in Thoracic Outlet Syndrome

NCT05544721
View directory record Official record
Conditions
Thoracic Outlet Syndrome
Interventions
Ropivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Phase 2 Interventional

Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery

NCT06199999
View directory record Official record
Conditions
Postoperative Delirium, Pain, Postoperative, Degenerative Disc Disease
Interventions
Erector Spinae Block, Local infiltration with local anesthetic
Procedure
Lead sponsor
Rashmi Mueller
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

CPB Versus Sham Treatment for Pain Management in Small Duct Chronic Pancreatitis

NCT02054910
View directory record Official record
Conditions
Chronic Pancreatitis
Interventions
Celiac Plexus Block, Sham
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

Spirox Latera™ Implant Support of Lateral Nasal Wall Cartilage (LATERAL-OR) Study

NCT02952313
View directory record Official record
Conditions
Nasal Obstruction
Interventions
Nasal Implant
Device
Lead sponsor
Spirox, Inc.
Industry
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
12
States / cities
Beverly Hills, California • Boca Raton, Florida • Boynton Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Oct 28, 2026, 10:18 AM EDT
Recruiting Phase 3 Interventional

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

NCT05611242
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
MT+CAS with IV-AP, MT+CAS with PO-AP, MT+CAT with PO-AP
Procedure
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years to 79 Years
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
60
States / cities
Mobile, Alabama • Glendale, California • Irvine, California + 54 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

NCT02140970
View directory record Official record
Conditions
Disorder of Urinary Stent, Ureteral Spasm, Ureteropelvic Junction Obstruction, Urolithiasis
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
4 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Oct 28, 2026, 10:18 AM EDT
Recruiting Not applicable Interventional

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

NCT06538376
View directory record Official record
Conditions
Pulmonary Edema, Pneumonia, Atelectasis, Pleural Effusion, Acute Rejection of Lung Transplant (Disorder), Airway Obstruction, Rib Fractures, Acute Copd Exacerbation, Asthma COPD, Pulmonary Embolism, Hemothorax, Pneumothorax, Mesothelioma, Diaphragmatic Paralysis
Interventions
Portable Dynamic Digital Radiography (DDR)
Diagnostic Test
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 28, 2026, 10:18 AM EDT
Completed No phase listed Observational

SpyGlass™ Discover Percutaneous

NCT04580940
View directory record Official record
Conditions
Pancreatic Diseases, Bile Duct Obstruction, Bile Duct Diseases
Interventions
SpyGlass™ Discover Digital System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 28, 2026, 10:18 AM EDT
Completed No phase listed Observational Results available

ASSIST Registry Studying Various Operator Techniques

NCT03845491
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Mechanical Thrombectomy
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years and older
Enrollment
1,492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
38
States / cities
Mesa, Arizona • Fontana, California • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Serratus Anterior Plane Block Combined With Transversus Thoracic Muscle Plane Block Versus Conventional Local Anesthetic Infiltration for SICD Implantation: A Randomized Controlled Trial

NCT05092490
View directory record Official record
Conditions
Serratus Anterior Plane Block, Transversus Thoracis Plane Block, Subcutaneous ICD
Interventions
Combined serratus anterior plane block and transversus thoracis plane block, Standard local infiltration technique
Procedure
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 28, 2026, 10:18 AM EDT
Enrolling by invitation Not applicable Interventional

Optimal Duration of Foley Catheter After Bulbar Urethroplasty

NCT07220980
View directory record Official record
Conditions
Urethral Stricture, Bulbar
Interventions
Early catheter removal, Later catheter removal
Device
Lead sponsor
Jane Kurtzman
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Burlington, Massachusetts • Buffalo, New York • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 28, 2026, 10:18 AM EDT
Not listed Not applicable Interventional

The Vesalio NeVa Stent Retriever Study for Treatment of Large Vessel Occlusion Strokes: CLEAR Study

NCT04514562
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
NeVa Stent Retrievers
Device
Lead sponsor
Vesalio
Industry
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
7
States / cities
Thousand Oaks, California • Jacksonville, Florida • Marietta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure

NCT05637970
View directory record Official record
Conditions
Arterial Occlusion, Cardiovascular Diseases, Hematoma
Interventions
Perclose, Statseal
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional Results available

Maintaining Patency in Implanted Port Catheters

NCT02354118
View directory record Official record
Conditions
Obstruction; Catheter, Infusion Catheter (Vascular), Catheter; Complications (Indwelling Catheter)
Interventions
Heparinized saline catheter flush, Saline-only catheter flush
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older
Enrollment
436 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
8
States / cities
Cincinnati, Ohio • Hamilton, Ohio • Oxford, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Oct 28, 2026, 10:18 AM EDT
Recruiting Not applicable Interventional

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

NCT05172960
View directory record Official record
Conditions
Aortic Stenosis, Severe
Interventions
SAPIEN X4 THV, SAPIEN X4S
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
Not listed
Enrollment
1,234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2037
U.S. locations
58
States / cities
La Jolla, California • Los Angeles, California • Newport Beach, California + 44 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Phase 3 Interventional Results available

Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusion

NCT01198327
View directory record Official record
Conditions
Retinal Vein Occlusion
Interventions
ranibizumab, Peripheral Laser
Drug · Other
Lead sponsor
Peter A Campochiaro, MD
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
6
States / cities
Beverly Hills, California • Sacremento, California • Augusta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2014 · Synced Oct 28, 2026, 10:18 AM EDT
Enrolling by invitation Not applicable Interventional

Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

NCT06614582
View directory record Official record
Conditions
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 23 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair

NCT04737980
View directory record Official record
Conditions
Rotator Cuff Tears, Shoulder Pain
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution, Dexamethasone
Drug
Lead sponsor
Hospital for Special Surgery Florida
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 28, 2026, 10:18 AM EDT
Completed Not applicable Interventional

A Prospective, Multi-Center, Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions

NCT02477579
View directory record Official record
Conditions
Chronic Total Occlusion of Coronary Artery
Interventions
NovaCross
Device
Lead sponsor
Nitiloop Ltd.
Industry
Eligibility
18 Years to 80 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
4
States / cities
Little Rock, Arkansas • Naperville, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 28, 2026, 10:18 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Methadone and Interscalene Block for Shoulder Surgery

NCT03084588
View directory record Official record
Conditions
Pain
Interventions
methadone, Interscalene block
Drug · Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 28, 2026, 10:18 AM EDT
Withdrawn Not applicable Interventional

Pain Relief Study of Ultrasound Guided Transverse Abdominis Plane(TAP)Block

NCT01217580
View directory record Official record
Conditions
Cesarean Section
Interventions
0.5% ropivacaine, 0.9% sodium chloride
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 28, 2026, 10:18 AM EDT