Independent directory Public ClinicalTrials.gov records United States
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Showing 217–240 of 760 matching trials from the live ClinicalTrials.gov search.
Conditions
OSA, Overweight or Obesity
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
15
States / cities
Long Beach, California • Rolling Hills Estates, California • San Diego, California + 12 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

CPAP Population Management

NCT04559737
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Case Management
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fontana, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea

NCT04121923
Conditions
Sleep Apnea, Obstructive
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Obstructive Sleep Apnea
Interventions
Upper Airway Muscle Exercise, Sham Exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 79 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
San Diego, California
Conditions
Obstructive Sleep Apnea
Interventions
bed positioning
Other
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Englewood, New Jersey
Conditions
Obstructive Sleep Apnea
Interventions
TAK-925, Placebo
Drug
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 67 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
18
States / cities
Alabaster, Alabama • Glendale, Arizona • Little Rock, Arkansas + 15 more
Conditions
OSA
Interventions
AD109
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Anniston, Alabama • Jacksonville, Florida • Monroe, North Carolina + 1 more
Conditions
Obstructive Sleep Apnea, Non-healing Wounds
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

NCT03307330
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

Obstructive Sleep Apnea and Metabolic Health

NCT02978937
Conditions
Sleep; Apnea, Metabolism Disorder
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 88 Years
Enrollment
850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Sleep Apnea
Interventions
Physical activity, Diet, Health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sleep, Obstructive Sleep Apnea, Insomnia
Interventions
Behavioral Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not listed Not applicable Interventional Accepts healthy volunteers

Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress

NCT00177892
Conditions
Obstructive Sleep Apnea, Metabolic Syndrome X
Interventions
sleep disruption, sleep with and without positive pressure
Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx

NCT03986671
Conditions
Obstructive Sleep Apnea, Amyotrophic Lateral Sclerosis, Muscular Dystrophies, Healthy
Interventions
Transmembrane EMG Oropharynx Probe
Device
Lead sponsor
Powell Mansfield Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Completed Early Phase 1 Interventional Accepts healthy volunteers

Remifentanil in Adults With OSA

NCT02898792
Conditions
Apnea, Sleep
Interventions
Targeted infusion of remifentanil
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Xyrem (X), Zolpidem (Z), Modafinil (M), Placebo (P)
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
St. Petersburg, Florida
Conditions
Obstructive Sleep Apnea
Interventions
F&P Full-Face Mask
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Obstructive Sleep Apnea of Adult
Interventions
structured adherence management program, Standard of care
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Gainesville, Florida
Conditions
Hypopnea, Sleep
Interventions
Mouth closure
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 89 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity, Obstructive Sleep Apnea Syndrome
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
8 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Rochester, New York
Conditions
Asthma, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Interventions
Inhaled Fluticasone Propionate
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Obstructive Sleep Apnea
Interventions
Attune Sleep Apnea System
Device
Lead sponsor
ApniCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
6
States / cities
Phoenix, Arizona • Burlingame, California • Menlo Park, California + 3 more
Completed Not applicable Interventional Results available

Auto-PAP Therapy For Improved Fetal Growth

NCT03318003
Conditions
Obstructive Sleep Apnea, Pregnancy
Interventions
Auto-PAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Differences in Efficacy Between Nasal and Oronasal Masks in the Treatment of OSA With CPAP

NCT01909674
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Switch CPAP mask type
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York