- Conditions
- Opioid-induced Constipation
- Interventions
- Methylnaltrexone Bromide, Placebo-Normal Saline
- Drug
- Lead sponsor
- St. John Health System, Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Southfield, Michigan
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 58
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Healthy, Opioid-induced Constipation
- Interventions
- TD-1211, Placebo
- Drug
- Lead sponsor
- Glycyx Therapeutics
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010
- U.S. locations
- 3
- States / cities
- Pasadena, California • San Antonio, Texas • Salt Lake City, Utah
- Conditions
- Cancer, Bowel Dysfunction
- Interventions
- alvimopan, placebo
- Drug
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 14
- States / cities
- Duarte, California • Fountain Valley, California • La Verne, California + 11 more
- Conditions
- Opioid-Induced Constipation
- Interventions
- methylnaltrexone, placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 4
- States / cities
- Laguna Hills, California • Lancaster, California • Flat Rock, North Carolina + 1 more
- Conditions
- Neoplasms, Constipation, Opioid-Related Disorders
- Interventions
- Methylnaltrexone bromide
- Drug
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Opioid-induced Constipation
- Interventions
- Methylnaltrexone
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2008
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Opioid-induced Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- East Hanover, New Jersey
- Conditions
- Constipation, Constipation Drug Induced
- Interventions
- Naloxegol 25 MG, Placebo pill
- Drug · Other
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 280 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Opioid-induced Constipation (OIC)
- Interventions
- TD-1211, Placebo
- Drug
- Lead sponsor
- Glycyx Therapeutics
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Constipation
- Interventions
- Lubiprostone, Senna
- Drug
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-induced Constipation
- Interventions
- RDC-1036 (ALKS 37), Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 11
- States / cities
- Sheffield, Alabama • Anaheim, California • Pasadena, California + 8 more
- Conditions
- Bowel Dysfunction
- Interventions
- SC MNTX
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2003
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Opioid-induced Bowel Dysfunction
- Interventions
- Lubiprostone, Placebo
- Drug
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 439 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 115
- States / cities
- Athens, Alabama • Birmingham, Alabama • Foley, Alabama + 89 more
- Conditions
- Constipation
- Interventions
- Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
- Drug
- Lead sponsor
- Shriners Hospitals for Children
- Other
- Eligibility
- 12 Years to 21 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Spokane, Washington
- Conditions
- Constipation
- Interventions
- naloxegol
- Drug
- Lead sponsor
- Joseph Ma
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Opioid-Induced Constipation
- Interventions
- Methylnaltrexone, Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 237 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 29
- States / cities
- Mobile, Alabama • Laguna Hills, California • Lancaster, California + 23 more
- Conditions
- Advanced Illness Patients With Opioid Induced Constipation
- Interventions
- SC Methylnaltrexone, SC Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Constipation
- Interventions
- N-methylnaltrexone bromide (MOA-728), placebo
- Drug · Other
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 460 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 78
- States / cities
- Mobile, Alabama • Sun City, Arizona • Tucson, Arizona + 69 more
- Conditions
- Opioid Induced Constipation
- Interventions
- TD-1211, Placebo
- Drug
- Lead sponsor
- Glycyx Therapeutics
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Pasadena, California
- Conditions
- Opioid-induced Constipation
- Interventions
- Naldemedine, Placebo
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 553 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 49
- States / cities
- Birmingham, Alabama • Homewood, Alabama • Goodyear, Arizona + 46 more
- Conditions
- Opioid-Induced Constipation
- Interventions
- Linaclotide 145 micrograms, Linaclotide 290 micrograms, Placebo
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 254 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 77
- States / cities
- Anniston, Alabama • Foley, Alabama • Phoenix, Arizona + 67 more
- Conditions
- Opioid Induced Bowel Dysfunction
- Interventions
- Naldemedine, Placebo
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- OIC
- Interventions
- ALKS 37, Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 91 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 13
- States / cities
- Anaheim, California • Orange, California • Daytona Beach, Florida + 10 more
- Conditions
- Opioid-Induced Bowel Dysfunction
- Interventions
- Lubiprostone 24
- Drug
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 439 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 120
- States / cities
- Birmingham, Alabama • Hueytown, Alabama • Mobile, Alabama + 95 more