- Conditions
- Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal
- Interventions
- Neonatal Morphine Solution, Methadone, Phenobarbital
- Drug
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 8
- States / cities
- Jacksonville, Florida • Portland, Maine • Boston, Massachusetts + 4 more
Search Results
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Neonatal Opioid Withdrawal Syndrome, Neonatal Abstinence Syndrome
- Interventions
- Sparrow Fledging Therapy System, Sham Sparrow Fledging Therapy System
- Device
- Lead sponsor
- Spark Biomedical, Inc.
- Industry
- Eligibility
- 33 Weeks to 1 Year
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 3
- States / cities
- Charleston, South Carolina • Dallas, Texas • San Antonio, Texas
- Conditions
- Opioid-Related Disorders
- Interventions
- Lofexidine
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 21 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1996
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Tolerance, Withdrawal, Addiction, Epigenetic Changes
- Interventions
- Not listed
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 87 participants
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Lofexidine
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 21 Years to 59 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1997
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Opiate Addiction
- Interventions
- Lofexidine, Placebo
- Drug
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 264 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 16
- States / cities
- Cerritos, California • Washington D.C., District of Columbia • Atlanta, Georgia + 13 more
- Conditions
- Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome
- Interventions
- Morphine PRN, Morphine scheduled
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- Up to 28 Days
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Opioid-Related Disorders, Opioid Withdrawal
- Interventions
- Buprenorphine/naloxone, Morphine, Tramadol
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Opioid Use Disorder
- Interventions
- Not listed
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Opioid Dependency
- Interventions
- Probuphine (buprenorphine implant)
- Drug
- Lead sponsor
- Titan Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 18
- States / cities
- Los Angeles, California • National City, California • Oceanside, California + 15 more
- Conditions
- Opioid Withdrawal, Chronic Pain
- Interventions
- Buprenorphine Patch, Placebo, Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (TMS)
- Drug · Device
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Opiate Use Disorder, Opiate Withdrawal Syndrome
- Interventions
- App Development and Open Pilot
- Other
- Lead sponsor
- Butler Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Neonatal Abstinence Syndrome, Substance Withdrawal, Neonatal
- Interventions
- Music Therapy
- Other
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 1 Minute to 1 Month
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Metairie, Louisiana
- Conditions
- Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
- Interventions
- Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride
- Device · Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 6
- States / cities
- Atlanta, Georgia
- Conditions
- Opioid Dependence, Opioid Withdrawal, Opioid Detoxification
- Interventions
- Buprenorphine
- Drug
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome, Drug Abuse in Pregnancy
- Interventions
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Drug
- Lead sponsor
- T. John Winhusen, PhD
- Other
- Eligibility
- 18 Years to 41 Years · Female only
- Enrollment
- 97 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 12
- States / cities
- Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more
- Conditions
- Opioid-use Disorder, Opioid Withdrawal, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome
- Interventions
- Medically-supervised withdrawal, Opioid agonist treatment, Comprehensive clinical care
- Other · Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 41 Years · Female only
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 4
- States / cities
- Asheville, North Carolina • Chapel Hill, North Carolina • Burlington, Vermont + 1 more
- Conditions
- Opioid Use Disorder, Opioid Withdrawal
- Interventions
- Buprenorphine/naloxone
- Drug
- Lead sponsor
- United Health Services Hospitals, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Binghamton, New York
- Conditions
- Heroin Dependence
- Interventions
- Buspirone
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 25 Years to 55 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2004
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Opioid Withdrawal (Disorder)
- Interventions
- Lofexidine, Placebo
- Drug
- Lead sponsor
- USWM, LLC (dba US WorldMeds)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 12
- States / cities
- Placentia, California • Rancho Mirage, California • Plantation, Florida + 9 more
- Conditions
- Cocaine Dependence, Opiate Dependence
- Interventions
- sugar pill, Carvedilol 25 mg, Carvedilol 50 mg
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Neonatal Opioid Withdrawal Syndrome
- Interventions
- Buprenorphine or Placebo, Morphine or Placebo
- Drug
- Lead sponsor
- Women and Infants Hospital of Rhode Island
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Opioid Withdrawal (Disorder)
- Interventions
- Standard of Care with Lofexidine, Standard of Care without Lofexidine
- Drug · Other
- Lead sponsor
- BioCorRx Pharmaceuticals Inc
- Other
- Eligibility
- 0 Hours to 6 Days
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Huntington, West Virginia
- Conditions
- Opioid Dependence, Acute Opioid Withdrawal Syndrome
- Interventions
- Lofexidine HCl, Placebo, Open Label Lofexidine HCL
- Drug
- Lead sponsor
- USWM, LLC (dba US WorldMeds)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 603 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 18
- States / cities
- Clovis, California • Escondido, California • San Diego, California + 15 more