- Conditions
- Opioid-Induced Constipation
- Interventions
- Methylnaltrexone bromide
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 26
- States / cities
- Mobile, Alabama • Laguna Hills, California • Lancaster, California + 20 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 58
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 670 participants
- Timeline
- 2006 – 2007
- U.S. locations
- 59
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 52 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Placebo, Naldemedine
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 49
- States / cities
- Phoenix, Arizona • Sun Lakes, Arizona • Little Rock, Arkansas + 46 more
- Conditions
- Low Back Pain
- Interventions
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release, Placebo
- Drug
- Lead sponsor
- Purdue Pharma LP
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 455 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 170
- States / cities
- Alabaster, Alabama • Birmingham, Alabama • Gulf Shores, Alabama + 137 more
- Conditions
- Constipation, Impaction, and Bowel Obstruction, Unspecified Adult Solid Tumor, Protocol Specific
- Interventions
- naloxone hydrochloride
- Drug
- Lead sponsor
- Dana-Farber Cancer Institute
- Other
- Eligibility
- 18 Years to 120 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2000
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Constipation, Constipation Drug Induced
- Interventions
- Naloxegol 25 MG, Placebo pill
- Drug · Other
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 280 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Opioid-induced Constipation
- Interventions
- Naldemedine, Placebo
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,246 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 99
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 96 more
- Conditions
- Opioid-Induced Constipation
- Interventions
- Methylnaltrexone, Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 804 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 2
- States / cities
- Raleigh, North Carolina
- Conditions
- Opioid-Induced Bowel Dysfunction
- Interventions
- Lubiprostone, Placebo
- Drug
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 437 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 109
- States / cities
- Tuscaloosa, Alabama • Phoenix, Arizona • Tempe, Arizona + 93 more
- Conditions
- Opioid-Induced Constipation (OIC)
- Interventions
- NKTR-118, Placebo
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 84 Years
- Enrollment
- 700 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 68
- States / cities
- Mobile, Alabama • Pell City, Alabama • Mesa, Arizona + 65 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Timeline
- 2006 – 2007
- U.S. locations
- 57
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 49 more
- Conditions
- Opioid-induced Bowel Dysfunction
- Interventions
- Lubiprostone, Placebo
- Drug
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 439 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 115
- States / cities
- Athens, Alabama • Birmingham, Alabama • Foley, Alabama + 89 more
- Conditions
- Opioid-induced Constipation (OIC)
- Interventions
- TD-1211, Placebo
- Drug
- Lead sponsor
- Glycyx Therapeutics
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Opioid-Induced Constipation
- Interventions
- NKTR-118, Placebo
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 81
- States / cities
- Huntsville, Alabama • Casa Grande, Arizona • Phoenix, Arizona + 78 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Naldemedine, Lubiprostone, Naloxegol
- Drug
- Lead sponsor
- BioDelivery Sciences International
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 34,532 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2030
- U.S. locations
- 1
- States / cities
- Wilmington, Delaware
- Conditions
- Opioid-induced Constipation
- Interventions
- ALKS 37, Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 157 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 20
- States / cities
- Mesa, Arizona • Phoenix, Arizona • National City, California + 17 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- East Hanover, New Jersey
- Conditions
- Cancer, Constipation, Pain
- Interventions
- Naloxegol, Placebo
- Drug
- Lead sponsor
- Hospice of Henderson County, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 3
- States / cities
- New York, New York • Flat Rock, North Carolina • Cleveland, Ohio
- Conditions
- OIC
- Interventions
- TD-1211 IV [C14], TD-1211 PO [C14]
- Drug
- Lead sponsor
- Glycyx Therapeutics
- Industry
- Eligibility
- 18 Years to 50 Years · Male only
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Constipation
- Interventions
- Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
- Drug
- Lead sponsor
- Shriners Hospitals for Children
- Other
- Eligibility
- 12 Years to 21 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Spokane, Washington
- Conditions
- Advanced Illness Patients With Opioid Induced Constipation
- Interventions
- SC Methylnaltrexone, SC Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Opioid-induced Constipation
- Interventions
- Methylnaltrexone bromide, Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Opioid-induced Constipation
- Interventions
- Methylnaltrexone Bromide, Placebo-Normal Saline
- Drug
- Lead sponsor
- St. John Health System, Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Southfield, Michigan
- Conditions
- Opioid-induced Constipation
- Interventions
- RDC-1036 (ALKS 37), Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 11
- States / cities
- Sheffield, Alabama • Anaheim, California • Pasadena, California + 8 more