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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:43 AM EST

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Showing 25–48 of 163 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Optical Imaging Clear all
Completed Phase 2 Interventional

An OCT-Guided Variable Dosing Regimen With Ranibizumab for the Treatment of Neovascular AMD

NCT00373659
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration
Interventions
Ranibizumab (Lucentis)
Drug
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Nov 7, 2026, 4:43 AM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Know Your Pressures NYC

NCT05992415
View directory record Official record
Conditions
Glaucoma, Hypertension, Glaucoma, Suspect, Elevated Blood Pressure
Interventions
Virtual Automated Navigator Intervention with Health Education, Usual Care
Other
Lead sponsor
Columbia University
Other
Eligibility
40 Years and older
Enrollment
7,085 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Recruiting No phase listed Observational

OCT in Rare Chorioretinal Diseases

NCT02141308
View directory record Official record
Conditions
Retinal Artery Occlusions, Polypoidal Choroidal Vasculopathy, Retinal Arterial Macroaneurysm, Juxtafoveal Telangiecasia, Central Serous Chorioretinopathy
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
7 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Nov 7, 2026, 4:43 AM EST
Completed Not applicable Interventional Results available

Evaluation of Imaging of Peripheral Arteries by Optical Coherence Tomography and Intravascular Ultrasound Imaging

NCT03480685
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
IVUS and OCT Imaging
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Hinsdale, Illinois • Pottstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Nov 7, 2026, 4:43 AM EST
Completed Phase 2 Interventional

Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)

NCT00344227
View directory record Official record
Conditions
Neovascular Age-Related Macular Degeneration
Interventions
Lucentis (Ranibizumab)
Drug
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Nov 7, 2026, 4:43 AM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Polarization Sensitive Optical Coherence Tomography (PS-OCT) for Retinal Imaging

NCT02441777
View directory record Official record
Conditions
Healthy
Interventions
Polarization-Sensitive OFDI
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Nov 7, 2026, 4:43 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Nidek RS3000 Comparative Study

NCT01384487
View directory record Official record
Conditions
Glaucoma, Retinal Disease, Corneal Disease
Interventions
Not listed
Lead sponsor
Nidek Co. LTD.
Industry
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2012 · Synced Nov 7, 2026, 4:43 AM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

Monitoring and Predicting Breast Cancer Neoadjuvant Chemotherapy Response Using DOSI

NCT02725658
View directory record Official record
Conditions
Breast Tumor
Interventions
DOSI
Device
Lead sponsor
Beckman Laser Institute and Medical Center
Other
Eligibility
21 Years to 80 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
4
States / cities
Costa Mesa, California • Irvine, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Nov 7, 2026, 4:43 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)

NCT02033486
View directory record Official record
Conditions
Breast Cancer
Interventions
TOBI + DBT
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
30 Years to 80 Years · Female only
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Nov 7, 2026, 4:43 AM EST
Not listed Phase 4 Interventional

Dupilmuab for Atopic Dermatitis Monitored With Noninvasive Imaging.

NCT05265234
View directory record Official record
Conditions
Eczema, Atopic Dermatitis
Interventions
Dupilumab, Optical Coherence Tomography, Reflectance confocal microscopy
Drug · Device
Lead sponsor
OptiSkin Medical
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Nov 7, 2026, 4:43 AM EST
Recruiting Not applicable Interventional

Multi-modal Imaging of Myofascial Pain - Phase 2

NCT07322445
View directory record Official record
Conditions
Myofascial Pain
Interventions
50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution, Dry Needling
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease

NCT05082402
View directory record Official record
Conditions
Cardiovascular Diseases, Retina; Change
Interventions
Swept Source Optical Coherence Tomography Angiography
Diagnostic Test
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 95 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optical Imaging Measurement of Intravascular Solution Efficacy Trial

NCT01743872
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Contrast Injection, Dextran Injection, CO2 Injection, Heparinized Normal Saline Injection
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Nov 7, 2026, 4:43 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

NCT01212029
View directory record Official record
Conditions
Cognition
Interventions
Behavioral measures, fNIRS Devices & Application, Physiological measures
Behavioral · Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 99 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Nov 7, 2026, 4:43 AM EST
Completed Phase 1 Interventional

Fluorescent Dyes for Lymph Node Mapping

NCT01095913
View directory record Official record
Conditions
Breast Cancer
Interventions
Indocyanine green (ICG)
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Nov 7, 2026, 4:43 AM EST
Not listed No phase listed Observational Accepts healthy volunteers

Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System

NCT00267449
View directory record Official record
Conditions
Breast Cancer
Interventions
SoftScan Optical Breast Imaging System
Device
Lead sponsor
ART Advanced Research Technologies Inc.
Industry
Eligibility
20 Years to 80 Years · Female only
Enrollment
950 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
3
States / cities
La Jolla, California • Stanford, California • Stuart, Florida
Source: ClinicalTrials.gov public record
Updated Sep 11, 2007 · Synced Nov 7, 2026, 4:43 AM EST
Completed Not applicable Interventional

Feasibility of Intraoperative Optical Imaging and Spectroscopy in Brain Tumors

NCT01627535
View directory record Official record
Conditions
Brain Tumor
Interventions
Interoperative Optical Imaging and Spectroscopy
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Nov 7, 2026, 4:43 AM EST
Terminated Not applicable Interventional Results available

Optical Imaging of Head and Neck Cancer

NCT01456143
View directory record Official record
Conditions
Squamous Cell Carcinoma, Neoplasia, Head and Neck Cancer
Interventions
High Resolution Microendoscopy (HRME), Proflavine hemisulfate
Device · Other
Lead sponsor
Sharmila Anandasabapathy, MD
Individual
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2018 · Synced Nov 7, 2026, 4:43 AM EST
Recruiting Phase 2 Interventional

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

NCT05626114
View directory record Official record
Conditions
Geographic Atrophy
Interventions
OpRegen
Biological
Lead sponsor
Genentech, Inc.
Industry
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
15
States / cities
Beverly Hills, California • Sacramento, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Recruiting No phase listed Observational Accepts healthy volunteers

Functional and Structural Imaging for Glaucoma

NCT01957267
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 85 Years
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2031
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Not yet recruiting Phase 2 Interventional

FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma

NCT07609472
View directory record Official record
Conditions
High-Grade Glioma (WHO III-IV)
Interventions
FG001
Drug
Lead sponsor
FluoGuide A/S
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Miami, Florida • Lebanon, New Hampshire • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Not yet recruiting No phase listed Observational

3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study

NCT07726524
View directory record Official record
Conditions
Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type, Anorexia Nervosa Restricting Type, Anorexia Nervosa With Significantly Low Body Weight, Body Composition Changes, Growth & Development, Malnutrition Severe, Malnutrition, Calorie
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 26 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
San Francisco, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Nov 7, 2026, 4:43 AM EST
Terminated Phase 1 Interventional

Cetuximab IRDye800 Study as an Optical Imaging Agent to Detect Cancer During Surgical Procedures

NCT01987375
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Cetuximab-IRDye800
Drug
Lead sponsor
Eben Rosenthal
Other
Eligibility
19 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Nov 7, 2026, 4:43 AM EST
Terminated No phase listed Observational

Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging

NCT01717937
View directory record Official record
Conditions
Age-related Macular Degeneration, Diabetic Retinopathy, Hypertensive Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion
Interventions
Phase variance optical coherence tomography (PV-OCT)
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Nov 7, 2026, 4:43 AM EST