- Conditions
- Osteoarthritis, Knee
- Interventions
- 30 minute treadmill walk
- Behavioral
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 55 Years to 70 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Newark, Delaware
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 409–432
of 1,212
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Interventions
- Tranexamic Acid Pill, Placebo
- Drug
- Lead sponsor
- Campbell Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Germantown, Tennessee
- Conditions
- Severe Osteoarthritis of the Knee
- Interventions
- Ampion, Saline
- Biological · Drug
- Lead sponsor
- Ampio Pharmaceuticals. Inc.
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 1,043 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Englewood, Colorado
- Conditions
- Osteoarthritis, Knee
- Interventions
- ITIS diet
- Dietary Supplement
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Pain
- Interventions
- Voltaren Gel
- Drug
- Lead sponsor
- HALEON
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 2
- States / cities
- Marrero, Louisiana • San Antonio, Texas
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteonecrosis
- Interventions
- Signature Custom Guides, Conventional Instrumentation
- Device · Procedure
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 266 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 7
- States / cities
- Elkhart, Indiana • Rockville, Maryland • Columbia, Missouri + 4 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Pulse Radiofrequency, Standard of Care Intra- Articular Injection, Placebo Intra-Articular Injection
- Procedure
- Lead sponsor
- Center For Interventional Pain and Spine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Exton, Pennsylvania
- Conditions
- Osteoarthritis, Knee, Microfragmented Adipose Tissue, Platelet-Rich Plasma
- Interventions
- Platelet Rich Plasma
- Device
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Osteoarthritis
- Interventions
- Orforglipron, Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 800 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 26
- States / cities
- Phoenix, Arizona • Tempe, Arizona • Huntington Beach, California + 22 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Engage Partial Knee
- Device
- Lead sponsor
- JIS Research Institute
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- New Albany, Ohio
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Osteoarthritis
- Interventions
- Squat Biofeedback, Standard Care
- Procedure
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 13 Years to 35 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Autoimmune Diseases, Systemic Inflammatory Process, Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis
- Interventions
- Fish Oil, Vitamin D, placebo pill
- Drug · Dietary Supplement · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 25,871 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Pain, Osteoarthritis
- Interventions
- active low-intensity transcranial electrical stimulation/active transcranial ultrasound, Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound
- Device
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Patellofemoral Osteoarthritis
- Interventions
- HYMOVIS plus Physical Exercise Program (PEP), Physical Exercise Program (PEP) alone
- Device · Other
- Lead sponsor
- Fidia Pharma USA Inc.
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 10
- States / cities
- Tucson, Arizona • Encinitas, California • Los Angeles, California + 5 more
- Conditions
- Knee Osteoarthritis (OA)
- Interventions
- Participants are given Ibuprofen 400 mg to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times., Participants are given a placebo to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times.
- Drug
- Lead sponsor
- David Grant U.S. Air Force Medical Center
- Federal
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Travis AFB, California
- Conditions
- Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
- Interventions
- Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction
- Biological · Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • New York, New York
- Conditions
- Symptomatic Knee Osteoarthritis
- Interventions
- DFV890, Placebo
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 115 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 7
- States / cities
- Phoenix, Arizona • El Cajon, California • Colorado Springs, Colorado + 4 more
- Conditions
- Osteoarthritis
- Interventions
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg, CR845 5 mg
- Drug
- Lead sponsor
- Cara Therapeutics, Inc.
- Industry
- Eligibility
- 25 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 5
- States / cities
- Omaha, Nebraska • Las Vegas, Nevada • Greensboro, North Carolina + 2 more
- Conditions
- Osteoarthritis
- Interventions
- Evicel fibrin sealant
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 20 Years to 90 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis
- Interventions
- Total and Unicompartment Knee Replacement
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Leesburg, Florida
- Conditions
- Osteoarthritis
- Interventions
- Diet & Exercise, Attention Control
- Behavioral
- Lead sponsor
- Wake Forest University
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 823 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2021
- U.S. locations
- 3
- States / cities
- Chapel Hill, North Carolina • Waynesville, North Carolina • Winston-Salem, North Carolina
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- Neuromuscular electrical stimulation, Voluntary exercise
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Osteoarthritis, Knee
- Interventions
- AXS-02, Placebo
- Drug
- Lead sponsor
- Axsome Therapeutics, Inc.
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 346 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 54
- States / cities
- Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 49 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- iTotal PS Knee Replacement System, Off-the-Shelf Knee Replacement System
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland