- Conditions
- Osteoarthritis, Knee
- Interventions
- Stepped Exercise Program, Arthritis Education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 345 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 121–144
of 1,212
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Joint Disease
- Interventions
- Medacta GMK Sphere® Medial-Pivot Knee Prosthesis, Medacta GMK PS Posterior Stabilized Knee Prosthesis
- Device
- Lead sponsor
- David F. Scott, MD
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 218 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2023
- U.S. locations
- 1
- States / cities
- Spokane, Washington
- Conditions
- Osteoarthritis
- Interventions
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Other
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis, Mild Cognitive Impairment, MCI, Mild Cognitive Impairment (MCI), Dementia
- Interventions
- Well-formulated ketogenic diet
- Other
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 55 Years to 75 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Fairway, Kansas
- Conditions
- Low Back Pain, Knee Osteoarthritis, Neck Pain
- Interventions
- Standard Physical Therapy care
- Other
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Shawnee Mission, Kansas
- Conditions
- Knee Osteoarthristis
- Interventions
- Physical Rehab, Focused Shockwave Therapy
- Other · Device
- Lead sponsor
- Pulse Wave USA
- Industry
- Eligibility
- Not listed
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 1
- States / cities
- Westminster, Colorado
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 7
- States / cities
- El Cajon, California • Sherman Oaks, California • Miami, Florida + 4 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Educational handout, Verbal script, Hyaluronic Acid
- Other · Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
- Interventions
- POPOP (preoperative patient optimization program), SOC (standard of care)
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 4
- States / cities
- Canoga Park, California • San Diego, California • Hialeah, Florida + 1 more
- Conditions
- Knee Osteoarthritis
- Interventions
- CyMedica e-vive NMES
- Device
- Lead sponsor
- CyMedica Orthopedics, Inc
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 159 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Tucson, Arizona
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Interventions
- Celecoxib
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 875 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 67
- States / cities
- Huntsville, Alabama • Peoria, Arizona • Phoenix, Arizona + 58 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- hylan G-F 20, 1% sodium hyaluronate
- Device
- Lead sponsor
- American Orthopaedic Society for Sports Medicine
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 198 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Portsmouth, Virginia
- Conditions
- Osteoarthritis
- Interventions
- PN 400 (VIMOVO), celebrex, Placebo, Rescue Antacid
- Drug
- Lead sponsor
- POZEN
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 614 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Osteoarthritis of the Knee
- Interventions
- 1.2% Sodium Hyaluronate, Buffered Saline
- Device
- Lead sponsor
- Ferring Pharmaceuticals
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 596 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 34
- States / cities
- Homewood, Alabama • Tucson, Arizona • Hot Springs, Arkansas + 30 more
- Conditions
- Osteoarthritis
- Interventions
- Total knee
- Procedure
- Lead sponsor
- Heekin Orthopedic Research Institute
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- Chestnut Hill, Massachusetts
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Blood Draw, Joint Aspirate Harvest
- Procedure
- Lead sponsor
- Scuderi, Gaetano J., M.D.
- Other
- Eligibility
- 19 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Knee Osteoarthritis, Knee Replacement
- Interventions
- Not listed
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 161 participants
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Adaptive Daily Step Promotion
- Behavioral
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Osteoarthritis
- Interventions
- Evaluation of Augmented Reality technology in TKA compared to standard TKA
- Other
- Lead sponsor
- Foundation for Orthopaedic Research and Education
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Osteoarthritis, OA, Knee Osteoarthritis
- Interventions
- Autologous Alpha-2 Macroglobulin Rich Plasma (A2MRP)
- Biological
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Osteoarthritis, Post Traumatic Degenerative Disease
- Interventions
- EPIK™ uni-compartmental knee
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Kyle, Texas
- Conditions
- Osteoarthritis
- Interventions
- LNA043, Placebo
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 576 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 23
- States / cities
- Phoenix, Arizona • Tucson, Arizona • La Mesa, California + 20 more