- Conditions
- Post-traumatic Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40 mg
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 20 Years to 50 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
Search Results
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
- Interventions
- Modular powered orthosis
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Moderate Varus, Valgus or Flexion Deformities, Avascular Necrosis of the Femoral Condyle
- Interventions
- Zimmer Persona Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 737 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2027
- U.S. locations
- 14
- States / cities
- Denver, Colorado • Fort Collins, Colorado • Parker, Colorado + 11 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Genicular nerve radiofrequency ablation, Pain Management Radiofrequency Kit
- Procedure · Device
- Lead sponsor
- Millennium Pain Center
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 3
- States / cities
- Bloomington, Illinois • Decatur, Illinois • Peoria, Illinois
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006 32 mg
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 17
- States / cities
- Tucson, Arizona • Anaheim, California • Canoga Park, California + 14 more
- Conditions
- Chronic Knee Pain, Osteoarthritis, Knee
- Interventions
- Nerve Block with Radiofrequency Ablation, Nerve Block with Sham Radiofrequency Ablation
- Procedure
- Lead sponsor
- Randall Brewer, MD, CPI
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Shreveport, Louisiana
- Conditions
- Pain
- Interventions
- Voltaren Gel
- Drug
- Lead sponsor
- HALEON
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 2
- States / cities
- Marrero, Louisiana • San Antonio, Texas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Pentosan Polysulfate Sodium twice weekly, Placebo
- Drug
- Lead sponsor
- Paradigm Biopharmaceuticals Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 466 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 40
- States / cities
- Peoria, Arizona • Tucson, Arizona • Anaheim, California + 33 more
- Conditions
- Osteoarthritis Knee Pain
- Interventions
- Duloxetine, Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 256 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 3
- States / cities
- Fort Myers, Florida • Edison, New Jersey • Lake Jackson, Texas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Cingal, Triamcinolone Hexacetonide (TH), Placebo
- Drug
- Lead sponsor
- Anika Therapeutics, Inc.
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 26
- States / cities
- Chandler, Arizona • Tucson, Arizona • Anaheim, California + 21 more
- Conditions
- Osteoarthritis
- Interventions
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg, CR845 5 mg
- Drug
- Lead sponsor
- Cara Therapeutics, Inc.
- Industry
- Eligibility
- 25 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 5
- States / cities
- Omaha, Nebraska • Las Vegas, Nevada • Greensboro, North Carolina + 2 more
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain, Knee Extension
- Interventions
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Osteoarthritis (OA) of the Knee
- Interventions
- oral suzetrigine, oral Oxycodone
- Drug
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 21 Years to 89 Years
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Osteoarthritis
- Interventions
- PH-797804, Placebo, Naproxen, Naproxen + PH-797804
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 172 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 26
- States / cities
- Paramount, California • Spring Valley, California • Valley Village, California + 20 more
- Conditions
- Osteoarthritis, Chronic Pain
- Interventions
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release), Placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 547 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 81
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 69 more
- Conditions
- Chronic Pain, Osteoarthritis, Knee
- Interventions
- Oxytocin, Placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Knee Osteoarthritis
- Interventions
- Mindfulness-Based Stress Reduction, Health Enhancement Program
- Behavioral
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Davis, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006, TCA IR
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 229 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 2
- States / cities
- Tucson, Arizona • Duncansville, Pennsylvania
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Interventions
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Drug
- Lead sponsor
- F. Johannes Plate
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis
- Interventions
- Hyalgan (sodium hyaluronate)
- Drug
- Lead sponsor
- Sanofi
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Osteoarthritis Knee Pain
- Interventions
- SL1002, Normal Saline
- Drug
- Lead sponsor
- Saol Therapeutics Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 21
- States / cities
- Roseville, California • San Diego, California • Greenwood Village, Colorado + 18 more
- Conditions
- Osteoarthritis
- Interventions
- hydrocodone / acetaminophen extended release, Placebo
- Drug
- Lead sponsor
- Abbott
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 873 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 83
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 68 more
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic
- Interventions
- Shoulder/Hip/Knee Embolization with Embozene Microspheres
- Device
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 25 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 4
- States / cities
- Canoga Park, California • San Diego, California • Hialeah, Florida + 1 more