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ClinicalTrials.gov public records Last synced Sep 12, 2026, 3:43 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Pain Levels Clear all
Withdrawn No phase listed Observational

Real-Time Accurate Pathology Inspection and Decompression Study

NCT05347108
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Chronic, Pain, Back, Pain, Neck, Radiculopathy
Interventions
laser-assisted neural decompression (LAND) procedure
Procedure
Lead sponsor
KM Clinical Research Group
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lā‘ie, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Phase 4 Interventional

Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study

NCT02202369
View directory record Official record
Conditions
Single Level Lumbar Decompression and Fusion Spine Surgery
Interventions
Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
Other
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain

NCT04006392
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Erchonia FX-635, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Mesa, Arizona • Costa Mesa, California • Hialeah, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

NCT03347708
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
IDCT, Saline Solution, Sodium Hyaluronate
Biological · Drug
Lead sponsor
DiscGenics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Phase 2 Interventional Results available

Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury

NCT02736890
View directory record Official record
Conditions
Neuropathic Back Pain, Spinal Cord Injury
Interventions
Botulinum Toxin A, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Not applicable Interventional

Effect of Acupuncture on Symptoms of Diarrhea and Pain in IBS

NCT00219505
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
acupuncture
Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

The Effect of Low Level Laser Therapy on Neck and Shoulder Pain

NCT03941912
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Erchonia EVRL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Largo, Florida • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Sep 12, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Open Label Extension Study of tDCS Plus Guided Imagery for Women With Chronic Pelvic Pain (CPP)

NCT04252040
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Active tDCS with guided imagery
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 64 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 22, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Not applicable Interventional

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

NCT04692597
View directory record Official record
Conditions
Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management, Integrative Medicine
Interventions
Phoenix Thera-Lase System, SHAM Phoenix Thera-Lase System
Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Effect of Low Level Laser Light on Low Back Pain

NCT02538523
View directory record Official record
Conditions
Low Back Pain
Interventions
Erchonia FX-635, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Chandler, Arizona • San Mateo, California • Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Study Evaluated the Effectiveness of Milnacipran to Reduce Pain Levels in Individuals With Chronic Migraine

NCT01393522
View directory record Official record
Conditions
Chronic Migraine
Interventions
Milnacipran, Placebo
Drug
Lead sponsor
Timothy Smith
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
St Louis, Missouri • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain

NCT02461225
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Erchonia® FX-635™, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

NCT00000409
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® 4 With New Anesthetic - Nasolabial Folds

NCT04087395
View directory record Official record
Conditions
Aging, Pain
Interventions
RHA®4 with new anesthetic agent, RHA®4-Lidocaine
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Beverly Hills, California • Coral Gables, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2022 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?

NCT01660412
View directory record Official record
Conditions
Pain
Interventions
Standard of Care First, ph Altered first
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 122 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2017 · Synced Sep 12, 2026, 3:43 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Study Evaluating AWBAT-D Versus the Standard of Care of Split-thickness Skin Graft Donor Sites

NCT01252836
View directory record Official record
Conditions
Healing of Donor Site, Pain Level
Interventions
AWBAT-D
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Sep 12, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Low Level Laser Therapy on Pain Induced by Placement of Orthodontic Separators in Pediatric Patients

NCT02211547
View directory record Official record
Conditions
Levels of Pain
Interventions
Epic 10 Diode Laser by Biolase Inc., Placebo
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 3 Interventional Results available

Pain Medicine for Wound Care Procedures

NCT00701909
View directory record Official record
Conditions
Wound Care, Pain Intensity, Hyperalgesia, Nausea, Vomiting, Hallucinations
Interventions
Morphine plus Ketamine, Morphine plus Saline (placebo)
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 12, 2026, 3:43 PM EDT
Terminated Phase 2 Interventional

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

NCT05740007
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
IW-3300 rectal foam, Placebo
Drug
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
53
States / cities
Mobile, Alabama • Scottsdale, Arizona • Tucson, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 12, 2026, 3:43 PM EDT
Recruiting No phase listed Observational

Quantify the Degree of Pain Relief of Pelvic Congestion Syndrome Following Gonadal Vein Embolization

NCT03794466
View directory record Official record
Conditions
Pelvic Congestive Syndrome, Pelvic Pain
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C

NCT04012996
View directory record Official record
Conditions
Symptomatic Cervical Disc Disease
Interventions
prodisc C SK and/or Vivo, Mobi-C Cervical Disc
Device
Lead sponsor
Centinel Spine
Industry
Eligibility
18 Years to 69 Years
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
30
States / cities
Flagstaff, Arizona • Beverly Hills, California • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 12, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional

Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

NCT04679844
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion, Back Pain
Interventions
MagnetOs Easypack Putty, Demineralized Bone Matrix or Fibers mixed with local autograft bone
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Irvine, California • Grand Rapids, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA

NCT04292392
View directory record Official record
Conditions
Knee Arthropathy
Interventions
preop ACB, followed by Intra-articular block during TKA surgery, preop ACB+IPACK block, preop ACB+IPACK block, followed by Intra-articular block during TKA surgery
Other
Lead sponsor
University of Louisville
Other
Eligibility
22 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 12, 2026, 3:43 PM EDT