Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 10, 2026, 11:53 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2569–2592 of 3,983 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Delirium
Interventions: Dexmedetomidine, Propofol, Midazolam; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Stanford, California

Conditions: Memory Disorders, Alzheimer Disease, Dementia, Cognitive Impairment, Frontotemporal Dementia
Interventions: COGNISION™ System; Device
Lead sponsor: Neuronetrix, Inc.; Industry
Eligibility: 60 Years to 90 Years
Enrollment: 204 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 7
States / cities: West Palm Beach, Florida • Lexington, Kentucky • Louisville, Kentucky + 4 more

Conditions: Mild Cognitive Impairment
Interventions: Aerobic exercise; Behavioral
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 55 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 2
States / cities: Seattle, Washington • Tacoma, Washington

Conditions: Head and Neck Cancer, Taste Dysfunction
Interventions: Miraculin, Miracle Fruit Placebo Cube; Drug · Dietary Supplement
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alzheimers Disease, Mild Cognitive Impairment
Interventions: 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation; Other
Lead sponsor: Emory University; Other
Eligibility: 50 Years to 90 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Chronic Pain, Early Cognitive Decline
Interventions: Mindfulness-based cognitive therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 50 Years to 120 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postoperative Delirium, Postoperative Cognitive Dysfunction
Interventions: fMRI, Montreal Cognitive Assessment (MoCA), Digital Clock Drawing Test Command and Copy, Wide Range Achievement Test reading subtest, Hopkins Verbal Learning Test (HVLT), General Depression Scale (GDS); Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 99 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Depression
Interventions: PST-MCI/AD Caregiving, NT-MCI/AD Caregiving; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: HIV, Cancer, Chronic Granulomatous Disease, Dock 8 Deficiency
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 9
States / cities: Orange, California • Washington D.C., District of Columbia • Tampa, Florida + 6 more

Conditions: Diabetes
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 417 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Aging, Vascular Stiffness, Vascular Dilation
Interventions: Calcium Acetate Oral Solution, Calcium Carbonate Oral Suspension; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years and older
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Multiple System Atrophy
Interventions: ATH434; Drug
Lead sponsor: Alterity Therapeutics; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Functional Disorder of Intestine
Interventions: Docusate, Bowel medications; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Meningioma, Skull Base Meningioma, Frontal Meningioma, Temporal Meningioma, Cognitive Impairment, Cognitive Decline, Post-Surgical Cognition
Interventions: Long-term Cognitive testing; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 50 participants
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Chronic Kidney Diseases, Pruritus
Interventions: CR845 0.25 mg Oral Tablet, CR845 0.5 mg Oral Tablet, CR845 1 mg Oral Tablet, Placebo Oral Tablet; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 269 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 60
States / cities: Birmingham, Alabama • Florence, Alabama • Phoenix, Arizona + 52 more

Conditions: Cardiovascular Risk Factor, Lipemia
Interventions: High-fat meal; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Mild Cognitive Impairment
Interventions: APOE genotype and Alzheimer's disease risk disclosure, Alzheimer's disease risk disclosure; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Ann Arbor, Michigan • Philadelphia, Pennsylvania

Conditions: Amputation Stumps, Neuroma
Interventions: Bupivacaine, Placebo; Drug
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sexual Dysfunction, Physiological, Body Image, Libido; Loss, Aversion
Interventions: Hypnotic Relaxation Intervention (HRI), Vulvovaginal Atrophy (VVA); Other · Device
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Sepsis, Sepsis and Septic Shock, Sepsis With Multiple Organ Dysfunction (MOD), Sepsis With Acute Organ Dysfunction, Sepsis, Severe, Sepsis at Intensive Care Unit, Sepsis, Severe Sepsis and Septic Shock, Sepsis, Septic Shock
Interventions: RNA and DNA Sequencing; Genetic
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Arterial Stiffness, White Matter Lesions, Cognitive Decline
Interventions: S-equol, Placebo; Drug
Lead sponsor: Akira Sekikawa; Other
Eligibility: 65 Years to 85 Years
Enrollment: 369 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Atlanta, Georgia • Winston-Salem, North Carolina • Pittsburgh, Pennsylvania

Conditions: Obstructive Sleep Apnea, Hypoxemia
Interventions: Continuous Positive Airway Pressure (CPAP); Device
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 21 Years and older
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Alzheimer Disease, Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Memory Loss, Memory Disorders, Memory Impairment
Interventions: Biomarker Data Collection; Other
Lead sponsor: GAP Innovations, PBC; Industry
Eligibility: 60 Years to 85 Years
Enrollment: 1,002 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 16
States / cities: Aventura, Florida • Coral Gables, Florida • Lady Lake, Florida + 13 more

Conditions: High Blood Pressure, Metabolic Syndrome, Insulin Resistance, Endothelial Dysfunction
Interventions: Aliskiren, Amlodipine, Placebo Aliskiren, Placebo Amlodipine; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Santa Monica, California

Search by objective public record fields.

Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

Evaluation of a Handheld Event Related Potential (ERP)/Quantitative Electroencephalography (qEEG) System (COGNISION™) as a Useful Cognitive Biomarker for Alzheimer's Disease.

Cognitive Effects of Aerobic Exercise for MCI Adults

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease

Mindfulness-based Cognitive Therapy for the Chronic Pain-early Cognitive Decline Co-morbidity Among Older Black Individuals in the Community; The Feeling of Being Open Pilot

fMRI Connectivity in Fracture Hip Patients

Prevention of Depression in Spouses of People With Cognitive Impairment

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

DHS MIND Metabolomics

Acetate and Age-associated Arterial Dysfunction

A Biomarker Study of ATH434 in Participants With MSA

Bowel Function After Minimally Invasive Urogynecologic Surgery

Cognitive Status After Removal of Skull Base Meningioma

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1

Risk Evaluation and Education for Alzheimer's Disease (REVEAL) IV

Pathophysiology of Post Amputation Pain

Women's Interventions for Sexual Health: WISH

Role of Transposable Elements in Septic Immune Aging

Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers

Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea

A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes)

Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome