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ClinicalTrials.gov public records Last synced Nov 8, 2026, 1:37 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 3,978 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
Interventions: the multi-domain Tai Chi Digital therapy Software Application; Device
Lead sponsor: Tim Shi; Other
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Ellicott City, Maryland

Conditions: HIV Seropositivity, Kaposi's Sarcoma, HIV Infections
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 13 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Amnestic Mild Cognitive Impairment, Alzheimer's Disease
Interventions: Insulin (Humulin® R U-100), Placebo; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 55 Years to 85 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 25
States / cities: Phoenix, Arizona • Irvine, California • New Haven, Connecticut + 18 more

Conditions: Sleep Apnea
Interventions: Induction of flow limitation; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chemo Brain, Chemotherapy-related Cognitive Impairment, Chemo Fog, Breast Cancer, Chemobrain
Interventions: Transdermal nicotine, Placebo Transdermal Patch; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 35 Years to 80 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Cancer, Fatigue
Interventions: Not listed
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 18 Years to 100 Years · Male only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Down Syndrome
Interventions: Donepezil HCl, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 10 Years to 17 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 31
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 25 more

Conditions: Aging, Endothelial Dysfunction, Senescence
Interventions: Supplement with ginger extract, L-citrulline, Paullinia cupana, and muira puama; Dietary Supplement
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 2
States / cities: Los Angeles, California • Santa Monica, California

Conditions: Opioid-induced Bowel Dysfunction
Interventions: Lubiprostone, Placebo; Drug
Lead sponsor: Sucampo Pharma Americas, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 439 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 115
States / cities: Athens, Alabama • Birmingham, Alabama • Foley, Alabama + 89 more

Conditions: Menopause
Interventions: TSEC (Tissue-selective estrogen complexes), Placebo; Drug · Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 50 Years to 60 Years · Female only
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: MASH - Metabolic Dysfunction-Associated Steatohepatitis
Interventions: Rezdiffra, Resmetirom, ACTOS/pioglitazone, FARXIGA/dapagliflozin; Drug
Lead sponsor: Madrigal Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 16
States / cities: Chandler, Arizona • North Little Rock, Arkansas • Coronado, California + 12 more

Conditions: Microalbuminuria
Interventions: benazepril; Drug
Lead sponsor: Charles Drew University of Medicine and Science; Other
Eligibility: 18 Years to 70 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Atrial Fibrillation, Cognitive Symptom, Executive Dysfunction, Cognitive Change, Cognitive Impairment, Cognitive Impairment, Mild
Interventions: Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm; Other
Lead sponsor: David Brunk, PA-C, MMS; Other
Eligibility: 35 Years to 80 Years
Enrollment: 600 participants
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Heart Failure, Congestive, Myocardial Infarction, Ventricular Dysfunction, Left
Interventions: Not listed
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 34,810 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 144
States / cities: Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 121 more

Conditions: Type 2 Diabetes Mellitus
Interventions: Glucagon-Like Peptide- 1 (GLP-1) infusion, Placebo Comparator: Saline Infusion; Drug · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 45 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of, Brain Aging, Fatty Acids, Omega-3
Interventions: Alpha-Linolenic Acid (2.6 g/day), Placebo Control Group; Drug · Dietary Supplement
Lead sponsor: Michal Schnaider Beeri, Ph.D.; Other
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Alzheimer Disease, Mild Cognitive Impairment
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 55 Years and older
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2031
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Left Ventricular Dysfunction, Ventricular Dysfunction, Heart Diseases, Cardiovascular Diseases
Interventions: Use of Eko DUO electronic Stethoscope; Device
Lead sponsor: Eko Devices, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 307 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
Interventions: Brain imaging, Laryngeal sensory block with topical bupivacaine; Other · Drug
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years to 80 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild Cognitive Impairment, Age-related Cognitive Decline
Interventions: Music Training I; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 60 Years and older
Enrollment: 268 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia, Parkinson Disease, Concussion, Brain, Brain Tumor, Healthy
Interventions: Acute Exercise; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Fluid Retention Tissue, Perfusion; Complications
Interventions: Manual Lymphatic Drainage, Near infrared spectroscopy, Temperature, Tissue Dialectic Constant; Other · Device
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Mild Cognitive Impairment, Neuropsychiatric Syndrome
Interventions: tDCS; Device
Lead sponsor: University of Rochester; Other
Eligibility: 60 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Cystoid Macular Edema, Fuchs Dystrophy
Interventions: Optical Coherence Tomography; Diagnostic Test
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Search by objective public record fields.

TaiChi-DTx for Treating Long Covid Symptoms

Effects of Potent Antiretroviral Therapy on Kaposi s Sarcoma

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B

Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study

Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

Effect of a Daily Supplement on Plasma PAI-1 Levels

Opioid-induced Bowel Dysfunction (OBD) Pivotal Assessment of Lubiprostone (OPAL)

Raising Insulin Sensitivity in Post Menopause

Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis

Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat Microalbuminuria

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting

GLP-1 and Hypoglycemia

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease

Low Ejection Fraction in Single Lead ECG- Ochsner

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

Interventions to Attenuate Cognitive Decline: Keys to Staying Sharp

EXercise-induced PhysioLogical Adaptations In Neurological Disorders

Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction

CogT BEEM Study (a tDCS Study)

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only